Project measure / variable:   Crabbe1   bal12_doseB

ID, description, units MPD:15409   bal12_doseB   missteps crossing 12.7mm wide balance beam   [n]  dose 1.2 g/kg i.p.  
ethanol study
Data set, strains Crabbe1   inbred   8 strains     sex: both     age: 8-16wks
Procedure balance beam
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  STRAIN COMPARISON PLOT
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Crabbe1 - missteps crossing 12.7mm wide balance beam dose 1.2 g/kg i.p.



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means3.26   n 4.26   n
Median of the strain means3.30   n 3.37   n
SD of the strain means± 1.54 ± 2.50
Coefficient of variation (CV)0.472 0.587
Min–max range of strain means1.29   –   5.00   n 2.14   –   9.00   n
Mean sample size per strain5.0   mice 4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 11.8417 11.8417 1.5821 0.2133
strain 7 165.0239 23.5748 3.1498 0.0067
sex:strain 7 54.0681 7.724 1.032 0.4186
Residuals 60 449.0755 7.4846


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 5.0 0.0   2   0.0 0.0 5.0, 5.0 1.13
129S1/SvImJ m 9.0 1.73   3 1.0 0.192 8.0, 11.0 1.89
A/J f 3.17 3.54   2   2.5 1.12 0.67, 5.67 -0.06
A/J m 3.17 3.54   2   2.5 1.12 0.67, 5.67 -0.44
BALB/cByJ f 3.43 2.74   7 1.04 0.799 0.11
BALB/cByJ m 3.34 2.34   6 0.955 0.701 0.67, 6.67 -0.37
BTBR T+ Itpr3tf/J f 5.0 4.36   5 1.95 0.872 1.13
BTBR T+ Itpr3tf/J m 2.25 1.71   4 0.854 0.759 -0.8
C3H/HeJ f 4.62 4.05   4 2.02 0.876 0.88
C3H/HeJ m 7.33 3.54   2   2.5 0.482 4.83, 9.83 1.23
C57BL/6J f 1.33 1.37   6 0.558 1.02 -1.25
C57BL/6J m 2.14 1.21   7 0.459 0.567 -0.85
DBA/2J f 1.29 1.6   7 0.606 1.25 -1.28
DBA/2J m 3.4 2.41   5 1.08 0.708 -0.34
FVB/NJ f 2.24 1.77   7 0.669 0.792 -0.66
FVB/NJ m 3.47 4.54   7 1.72 1.31 -0.32


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 5.0 1.9345 8.8696 1.1304
129S1/SvImJ m 9.0 1.5795 12.1595 5.8405
A/J f 3.17 1.9345 7.0396 0.0
A/J m 3.17 1.9345 7.0396 0.0
BALB/cByJ f 3.4314 1.034 5.4998 1.3631
BALB/cByJ m 3.3367 1.1169 5.5708 1.1026
BTBR T+ Itpr3tf/J f 5.0 1.2235 7.4473 2.5527
BTBR T+ Itpr3tf/J m 2.25 1.3679 4.9862 0.0
C3H/HeJ f 4.6225 1.3679 7.3587 1.8863
C3H/HeJ m 7.33 1.9345 11.1996 3.4604
C57BL/6J f 1.3333 1.1169 3.5674 0.0
C57BL/6J m 2.1429 1.034 4.2112 0.0745
DBA/2J f 1.2857 1.034 3.3541 0.0
DBA/2J m 3.4 1.2235 5.8473 0.9527
FVB/NJ f 2.2357 1.034 4.3041 0.1673
FVB/NJ m 3.47 1.034 5.5384 1.4016


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 7.0 1.2487 9.4978 4.5022
A/J both 3.17 1.3679 5.9062 0.4338
BALB/cByJ both 3.384 0.761 4.9063 1.8618
BTBR T+ Itpr3tf/J both 3.625 0.9176 5.4605 1.7895
C3H/HeJ both 5.9762 1.1846 8.3459 3.6066
C57BL/6J both 1.7381 0.761 3.2604 0.2158
DBA/2J both 2.3429 0.801 3.945 0.7407
FVB/NJ both 2.8529 0.7312 4.3154 1.3903




  GWAS USING LINEAR MIXED MODELS