Project measure / variable:   Crabbe1   bal12_doseA

ID, description, units MPD:15408   bal12_doseA   missteps crossing 12.7mm wide balance beam   [n]  dose 1.0 g/kg i.p.  
ethanol study
Data set, strains Crabbe1   inbred   8 strains     sex: both     age: 8-16wks
Procedure balance beam
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  STRAIN COMPARISON PLOT
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Crabbe1 - missteps crossing 12.7mm wide balance beam dose 1.0 g/kg i.p.



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means2.42   n 3.86   n
Median of the strain means2.08   n 2.83   n
SD of the strain means± 1.51 ± 2.70
Coefficient of variation (CV)0.623 0.699
Min–max range of strain means0   –   5.33   n 0.335   –   9.00   n
Mean sample size per strain5.1   mice 4.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 17.7642 17.7642 3.0517 0.0859
strain 7 139.1139 19.8734 3.414 0.004
sex:strain 7 29.5052 4.215 0.7241 0.6521
Residuals 59 343.444 5.8211


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 5.33 3.21   3 1.86 0.603 3.0, 9.0 1.93
129S1/SvImJ m 9.0 5.66   2   4.0 0.629 5.0, 13.0 1.9
A/J f 0.0 0.0   3 0.0 0.0 -1.61
A/J m 0.335 0.474   2   0.335 1.41 -1.31
BALB/cByJ f 3.0 3.25   7 1.23 1.08 0.38
BALB/cByJ m 2.57 2.97   7 1.12 1.16 -0.48
BTBR T+ Itpr3tf/J f 2.0 2.45   5 1.1 1.22 -0.28
BTBR T+ Itpr3tf/J m 4.5 2.38   4 1.19 0.529 1.0, 6.0 0.24
C3H/HeJ f 3.08 0.957   4 0.479 0.311 1.83, 3.83 0.44
C3H/HeJ m 6.33 0.707   2   0.5 0.112 5.83, 6.83 0.91
C57BL/6J f 2.17 1.94   6 0.792 0.896 -0.17
C57BL/6J m 2.5 1.76   6 0.719 0.704 -0.5
DBA/2J f 1.83 1.33   6 0.543 0.725 -0.39
DBA/2J m 3.0 2.45   6 1.0 0.816 -0.32
FVB/NJ f 1.95 1.91   7 0.721 0.979 -0.31
FVB/NJ m 2.66 2.95   5 1.32 1.11 -0.45


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 5.3333 1.393 8.1207 2.546
129S1/SvImJ m 9.0 1.706 12.4138 5.5862
A/J f 0.0 1.393 2.7873 -2.7873
A/J m 0.335 1.706 3.7488 -3.0788
BALB/cByJ f 3.0029 0.9119 4.8276 1.1781
BALB/cByJ m 2.5743 0.9119 4.399 0.7496
BTBR T+ Itpr3tf/J f 2.0 1.079 4.1591 -0.1591
BTBR T+ Itpr3tf/J m 4.5 1.2063 6.9139 2.0861
C3H/HeJ f 3.08 1.2063 5.4939 0.6661
C3H/HeJ m 6.33 1.706 9.7438 2.9162
C57BL/6J f 2.1667 0.985 4.1376 0.1957
C57BL/6J m 2.5 0.985 4.4709 0.5291
DBA/2J f 1.8333 0.985 3.8043 -0.1376
DBA/2J m 3.0 0.985 4.9709 1.0291
FVB/NJ f 1.95 0.9119 3.7747 0.1253
FVB/NJ m 2.664 1.079 4.8231 0.5049


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 7.1667 1.1012 9.3702 4.9631
A/J both 0.1675 1.1012 2.3711 -2.0361
BALB/cByJ both 2.7886 0.6448 4.0789 1.4983
BTBR T+ Itpr3tf/J both 3.25 0.8092 4.8693 1.6307
C3H/HeJ both 4.705 1.0447 6.7955 2.6145
C57BL/6J both 2.3333 0.6965 3.727 0.9397
DBA/2J both 2.4167 0.6965 3.8103 1.023
FVB/NJ both 2.307 0.7064 3.7204 0.8936




  GWAS USING LINEAR MIXED MODELS