Project measure / variable:   Gavras1   BP

ID, description, units MPD:14401   BP   systolic blood pressure   [mmHg]  control  
sodium chloride study
Data set, strains Gavras1   inbred   11 strains     sex: both     age: 9-12wks
Procedure tail cuff
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  STRAIN COMPARISON PLOT
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Gavras1 - systolic blood pressure control



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains9 strains
Mean of the strain means110   mmHg 106   mmHg
Median of the strain means109   mmHg 106   mmHg
SD of the strain means± 8.17 ± 8.71
Coefficient of variation (CV)0.0746 0.0818
Min–max range of strain means95.1   –   120   mmHg 91.6   –   119   mmHg
Mean sample size per strain6.6   mice 6.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 23.7979 23.7979 0.5022 0.4805
strain 6 1776.0537 296.009 6.2471 < 0.0001
sex:strain 6 1204.3202 200.72 4.2361 0.0009
Residuals 81 3838.0275 47.3831


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
C3H/HeJ f 105.0 7.64   8 2.7 0.0724 94.9, 116.0 -0.52
C3H/HeJ m 97.5 6.22   7 2.35 0.0638 86.6, 104.0 -1.11
C57BL/10J m 91.6 4.88   3 2.82 0.0533 86.4, 96.1 -1.82
C57BL/6J f 109.0 7.11   8 2.51 0.0654 98.7, 119.0 0.0
C57BL/6J m 101.0 6.47   8 2.29 0.064 91.6, 112.0 -0.68
CBA/J f 112.0 12.0   3 6.93 0.107 100.0, 124.0 0.39
CBA/J m 113.0 5.82   8 2.06 0.0514 100.0, 119.0 0.78
LP/J m 106.0 10.5   4 5.23 0.099 90.3, 114.0 -0.07
NOD/ShiLtJ m 119.0 9.93   8 3.51 0.0834 102.0, 128.0 1.51
NZW/LacJ f 95.1 3.95   4 1.98 0.0415 90.7, 100.0 -1.8
NZW/LacJ m 113.0 4.27   4 2.14 0.0377 110.0, 119.0 0.78
PL/J f 117.0 10.4   7 3.93 0.0888 106.0, 133.0 1.03
PL/J m 112.0 9.83   7 3.71 0.0875 99.3, 125.0 0.66
RIIIS/J f 109.0 6.48   8 2.29 0.0595 95.0, 118.0 0.0
RIIIS/J m 105.0 4.23   7 1.6 0.0402 101.0, 112.0 -0.2
SWR/J f 120.0 8.99   8 3.18 0.0747 100.0, 129.0 1.42


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
AKR/J f 105.3125 2.4337 110.1548 100.4702
AKR/J m 108.0 2.4337 112.8423 103.1577
C3H/HeJ f 105.4125 2.4337 110.2548 100.5702
C3H/HeJ m 97.5429 2.6017 102.7195 92.3662
C57BL/6J f 108.7125 2.4337 113.5548 103.8702
C57BL/6J m 101.1875 2.4337 106.0298 96.3452
CBA/J f 112.0 3.9742 119.9074 104.0926
CBA/J m 113.125 2.4337 117.9673 108.2827
NZW/LacJ f 95.125 3.4418 101.973 88.277
NZW/LacJ m 113.25 3.4418 120.098 106.402
PL/J f 117.0 2.6017 122.1766 111.8234
PL/J m 112.3286 2.6017 117.5052 107.1519
RIIIS/J f 109.0 2.4337 113.8423 104.1577
RIIIS/J m 105.2857 2.6017 110.4623 100.1091


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
AKR/J both 106.6563 1.7209 110.0803 103.2322
C3H/HeJ both 101.4777 1.7813 105.0219 97.9335
C57BL/6J both 104.95 1.7209 108.374 101.526
CBA/J both 112.5625 2.3301 117.1986 107.9264
NZW/LacJ both 104.1875 2.4337 109.0298 99.3452
PL/J both 114.6643 1.8397 118.3247 111.0039
RIIIS/J both 107.1429 1.7813 110.6871 103.5987




  GWAS USING LINEAR MIXED MODELS