Project measure / variable:   Graubert1   GI_tumor_enu

ID, description, units MPD:11660   GI_tumor_enu   gastrointestinal (GI) tumor frequency rate   [score]  ENU  
ENU study
Data set, strains Graubert1   inbred   20 strains     sex: both     age: 13-68wks
Procedure histopathology
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  STRAIN COMPARISON PLOT
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Graubert1 - gastrointestinal (GI) tumor frequency rate ENU



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested20 strains20 strains
Mean of the strain means0.0563   score 0.0250   score
Median of the strain means0   score 0   score
SD of the strain means± 0.0959 ± 0.0815
Coefficient of variation (CV)1.70 3.26
Min–max range of strain means0   –   0.333   score 0   –   0.333   score
Mean sample size per strain6.1   mice 6.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0628 0.0628 1.6218 0.2043
strain 19 1.1971 0.063 1.6266 0.0527
sex:strain 19 0.6133 0.0323 0.8333 0.6655
Residuals 199 7.7083 0.0387


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.0 0.0   6 0.0 0.0 -0.59
129S1/SvImJ m 0.0 0.0   6 0.0 0.0 -0.31
A/J f 0.125 0.354   8 0.125 2.83 0.72
A/J m 0.167 0.408   6 0.167 2.45 1.74
AKR/J f 0.167 0.408   6 0.167 2.45 1.15
AKR/J m 0.0 0.0   6 0.0 0.0 -0.31
BALB/cByJ f 0.0 0.0   6 0.0 0.0 -0.59
BALB/cByJ m 0.0 0.0   6 0.0 0.0 -0.31
C3H/HeJ f 0.167 0.408   6 0.167 2.45 1.15
C3H/HeJ m 0.0 0.0   6 0.0 0.0 -0.31
C57BL/6J f 0.0 0.0   6 0.0 0.0 -0.59
C57BL/6J m 0.0 0.0   7 0.0 0.0 -0.31
C57L/J f 0.333 0.516   6 0.211 1.55 2.89
C57L/J m 0.0 0.0   6 0.0 0.0 -0.31
C58/J f 0.0 0.0   6 0.0 0.0 -0.59
C58/J m 0.0 0.0   6 0.0 0.0 -0.31
CAST/EiJ f 0.167 0.408   6 0.167 2.45 1.15
CAST/EiJ m 0.333 0.516   6 0.211 1.55 3.78
DBA/2J f 0.0 0.0   5 0.0 0.0 -0.59
DBA/2J m 0.0 0.0   7 0.0 0.0 -0.31
FVB/NJ f 0.0 0.0   6 0.0 0.0 -0.59
FVB/NJ m 0.0 0.0   6 0.0 0.0 -0.31
MOLF/EiJ f 0.0 0.0   2   0.0 0.0 -0.59
MOLF/EiJ m 0.0 0.0   5 0.0 0.0 -0.31
NOD/ShiLtJ f 0.0 0.0   6 0.0 0.0 -0.59
NOD/ShiLtJ m 0.0 0.0   6 0.0 0.0 -0.31
NZB/BlNJ f 0.0 0.0   6 0.0 0.0 -0.59
NZB/BlNJ m 0.0 0.0   6 0.0 0.0 -0.31
PERA/EiJ f 0.0 0.0   6 0.0 0.0 -0.59
PERA/EiJ m 0.0 0.0   6 0.0 0.0 -0.31
PL/J f 0.0 0.0   6 0.0 0.0 -0.59
PL/J m 0.0 0.0   6 0.0 0.0 -0.31
SJL/J f 0.0 0.0   4 0.0 0.0 -0.59
SJL/J m 0.0 0.0   6 0.0 0.0 -0.31
SM/J f 0.167 0.408   6 0.167 2.45 1.15
SM/J m 0.0 0.0   6 0.0 0.0 -0.31
SPRET/EiJ f 0.0 0.0   10 0.0 0.0 -0.59
SPRET/EiJ m 0.0 0.0   3 0.0 0.0 -0.31
SWR/J f 0.0 0.0   8 0.0 0.0 -0.59
SWR/J m 0.0 0.0   6 0.0 0.0 -0.31


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.0 0.0803 0.1584 -0.1584
129S1/SvImJ m 0.0 0.0803 0.1584 -0.1584
A/J f 0.125 0.0696 0.2622 -0.0122
A/J m 0.1667 0.0803 0.3251 0.0082
AKR/J f 0.1667 0.0803 0.3251 0.0082
AKR/J m 0.0 0.0803 0.1584 -0.1584
BALB/cByJ f 0.0 0.0803 0.1584 -0.1584
BALB/cByJ m 0.0 0.0803 0.1584 -0.1584
C3H/HeJ f 0.1667 0.0803 0.3251 0.0082
C3H/HeJ m 0.0 0.0803 0.1584 -0.1584
C57BL/6J f 0.0 0.0803 0.1584 -0.1584
C57BL/6J m 0.0 0.0744 0.1467 -0.1467
C57L/J f 0.3333 0.0803 0.4918 0.1749
C57L/J m 0.0 0.0803 0.1584 -0.1584
C58/J f 0.0 0.0803 0.1584 -0.1584
C58/J m 0.0 0.0803 0.1584 -0.1584
CAST/EiJ f 0.1667 0.0803 0.3251 0.0082
CAST/EiJ m 0.3333 0.0803 0.4918 0.1749
DBA/2J f 0.0 0.088 0.1736 -0.1736
DBA/2J m 0.0 0.0744 0.1467 -0.1467
FVB/NJ f 0.0 0.0803 0.1584 -0.1584
FVB/NJ m 0.0 0.0803 0.1584 -0.1584
MOLF/EiJ f 0.0 0.1392 0.2744 -0.2744
MOLF/EiJ m 0.0 0.088 0.1736 -0.1736
NOD/ShiLtJ f 0.0 0.0803 0.1584 -0.1584
NOD/ShiLtJ m 0.0 0.0803 0.1584 -0.1584
NZB/BlNJ f 0.0 0.0803 0.1584 -0.1584
NZB/BlNJ m 0.0 0.0803 0.1584 -0.1584
PERA/EiJ f 0.0 0.0803 0.1584 -0.1584
PERA/EiJ m 0.0 0.0803 0.1584 -0.1584
PL/J f 0.0 0.0803 0.1584 -0.1584
PL/J m 0.0 0.0803 0.1584 -0.1584
SJL/J f 0.0 0.0984 0.1941 -0.1941
SJL/J m 0.0 0.0803 0.1584 -0.1584
SM/J f 0.1667 0.0803 0.3251 0.0082
SM/J m 0.0 0.0803 0.1584 -0.1584
SPRET/EiJ f 0.0 0.0622 0.1227 -0.1227
SPRET/EiJ m 0.0 0.1136 0.2241 -0.2241
SWR/J f 0.0 0.0696 0.1372 -0.1372
SWR/J m 0.0 0.0803 0.1584 -0.1584


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.0 0.0568 0.112 -0.112
A/J both 0.1458 0.0531 0.2506 0.041
AKR/J both 0.0833 0.0568 0.1954 -0.0287
BALB/cByJ both 0.0 0.0568 0.112 -0.112
C3H/HeJ both 0.0833 0.0568 0.1954 -0.0287
C57BL/6J both 0.0 0.0547 0.108 -0.108
C57L/J both 0.1667 0.0568 0.2787 0.0546
C58/J both 0.0 0.0568 0.112 -0.112
CAST/EiJ both 0.25 0.0568 0.362 0.138
DBA/2J both 0.0 0.0576 0.1136 -0.1136
FVB/NJ both 0.0 0.0568 0.112 -0.112
MOLF/EiJ both 0.0 0.0823 0.1624 -0.1624
NOD/ShiLtJ both 0.0 0.0568 0.112 -0.112
NZB/BlNJ both 0.0 0.0568 0.112 -0.112
PERA/EiJ both 0.0 0.0568 0.112 -0.112
PL/J both 0.0 0.0568 0.112 -0.112
SJL/J both 0.0 0.0635 0.1253 -0.1253
SM/J both 0.0833 0.0568 0.1954 -0.0287
SPRET/EiJ both 0.0 0.0648 0.1277 -0.1277
SWR/J both 0.0 0.0531 0.1048 -0.1048




  GWAS USING LINEAR MIXED MODELS