Project measure / variable:   Donahue1   fat_wt

ID, description, units MPD:11512   fat_wt   weight of fat portion of body mass, head excluded   [g]  
Data set, strains Donahue1   inbred w/CC7   30 strains     sex: both     age: 15-16wks
Procedure DXA
Ontology mappings

  STRAIN COMPARISON PLOT
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Donahue1 - weight of fat portion of body mass, head excluded



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested30 strains30 strains
Mean of the strain means3.46   g 4.39   g
Median of the strain means3.10   g 4.21   g
SD of the strain means± 1.78 ± 1.83
Coefficient of variation (CV)0.515 0.418
Min–max range of strain means1.37   –   9.68   g 1.74   –   9.38   g
Mean sample size per strain10.2   mice 9.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 134.5961 134.5961 120.6853 < 0.0001
strain 29 1680.2365 57.9392 51.951 < 0.0001
sex:strain 29 241.586 8.3306 7.4696 < 0.0001
Residuals 547 610.05 1.1153


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 2.61 0.277   10 0.0875 0.106 2.1, 2.9 -0.48
129S1/SvImJ m 5.07 1.26   10 0.397 0.248 3.7, 7.6 0.37
129X1/SvJ f 3.79 0.458   10 0.145 0.121 3.1, 4.5 0.19
129X1/SvJ m 5.47 0.77   10 0.244 0.141 4.4, 7.0 0.59
A/J f 4.28 1.3   10 0.411 0.304 2.8, 6.5 0.46
A/J m 5.62 1.28   10 0.404 0.227 4.1, 7.9 0.67
AKR/J f 9.68 2.49   10 0.788 0.257 6.7, 13.6 3.49
AKR/J m 9.38 1.96   10 0.621 0.209 6.3, 13.4 2.72
BALB/cJ f 4.4 1.17   10 0.371 0.267 3.0, 7.1 0.53
BALB/cJ m 4.19 0.843   10 0.266 0.201 2.8, 5.4 -0.11
BTBR T+ Itpr3tf/J f 3.81 0.641   9 0.214 0.168 2.9, 4.8 0.2
BTBR T+ Itpr3tf/J m 4.23 1.1   10 0.348 0.26 2.7, 6.0 -0.09
BUB/BnJ f 3.37 0.556   10 0.176 0.165 2.3, 4.2 -0.05
BUB/BnJ m 3.59 1.09   10 0.345 0.304 1.7, 5.5 -0.44
C3H/HeJ f 4.78 1.11   10 0.351 0.232 3.2, 6.4 0.74
C3H/HeJ m 6.25 1.41   10 0.445 0.225 4.4, 8.1 1.01
C57BL/6J f 2.6 0.638   10 0.202 0.245 2.0, 4.0 -0.48
C57BL/6J m 4.38 1.23   10 0.388 0.28 3.2, 6.4 -0.01
C57L/J f 2.87 0.783   10 0.248 0.273 2.1, 4.7 -0.33
C57L/J m 4.99 1.61   10 0.511 0.324 2.9, 8.3 0.33
C58/J f 2.69 1.12   10 0.354 0.416 1.5, 4.2 -0.43
C58/J m 5.89 1.18   9 0.393 0.2 3.3, 7.3 0.82
CAST/EiJ f 1.63 0.291   10 0.092 0.178 1.3, 2.1 -1.03
CAST/EiJ m 1.94 0.272   10 0.0859 0.14 1.6, 2.3 -1.34
CZECHII/EiJ f 1.63 0.377   12 0.109 0.231 1.3, 2.7 -1.03
CZECHII/EiJ m 1.88 0.406   12 0.117 0.216 1.3, 2.6 -1.37
DBA/2J f 4.49 1.22   10 0.386 0.272 2.4, 6.9 0.58
DBA/2J m 6.25 1.64   10 0.519 0.263 3.5, 8.7 1.01
FVB/NJ f 4.14 0.876   10 0.277 0.212 3.0, 5.6 0.38
FVB/NJ m 3.4 0.981   10 0.31 0.289 2.2, 5.5 -0.54
JF1/MsJ f 3.05 0.887   11 0.267 0.29 1.9, 4.5 -0.23
JF1/MsJ m 7.45 1.67   10 0.527 0.224 5.1, 10.1 1.67
MOLF/EiJ f 1.37 0.134   10 0.0423 0.0976 1.2, 1.7 -1.17
MOLF/EiJ m 1.74 0.4   8 0.141 0.23 1.0, 2.2 -1.44
MSM/MsJ f 1.4 0.205   11 0.0618 0.146 1.1, 1.8 -1.16
MSM/MsJ m 1.82 0.363   9 0.121 0.199 1.3, 2.5 -1.4
NOD/ShiLtJ f 2.87 0.688   10 0.218 0.24 1.7, 3.7 -0.33
NOD/ShiLtJ m 3.78 0.592   10 0.187 0.157 3.0, 4.6 -0.33
NZB/BlNJ f 3.63 0.907   10 0.287 0.25 2.2, 5.0 0.1
NZB/BlNJ m 4.0 1.34   10 0.423 0.334 2.3, 6.5 -0.21
NZW/LacJ f 6.99 1.45   10 0.46 0.208 5.6, 9.9 1.98
NZW/LacJ m 4.96 1.71   10 0.541 0.345 2.8, 8.0 0.31
PERA/EiJ f 4.93 0.796   10 0.252 0.161 3.9, 6.6 0.83
PERA/EiJ m 3.89 0.375   10 0.119 0.0965 3.2, 4.4 -0.27
PL/J f 3.15 0.782   10 0.247 0.248 2.3, 4.8 -0.17
PL/J m 4.22 0.818   11 0.247 0.194 3.2, 6.1 -0.09
PWK/PhJ f 1.65 0.139   13 0.0386 0.0845 1.4, 1.8 -1.02
PWK/PhJ m 3.62 1.63   9 0.543 0.45 2.1, 7.5 -0.42
SEA/GnJ f 5.67 1.98   14 0.528 0.348 2.7, 8.7 1.24
SEA/GnJ m 7.59 1.77   10 0.56 0.233 3.9, 10.0 1.74
SJL/J f 2.86 0.495   10 0.156 0.173 2.1, 3.5 -0.34
SJL/J m 3.58 0.767   10 0.243 0.214 2.3, 4.3 -0.44
SM/J f 3.36 0.62   10 0.196 0.185 2.5, 4.3 -0.06
SM/J m 4.63 0.785   10 0.248 0.169 3.3, 5.9 0.13
SPRET/EiJ f 2.02 0.327   9 0.109 0.162 1.7, 2.5 -0.81
SPRET/EiJ m 3.41 1.09   10 0.343 0.318 2.0, 5.0 -0.53
SWR/J f 2.52 0.316   10 0.0998 0.125 2.1, 3.0 -0.53
SWR/J m 2.45 0.584   10 0.185 0.238 1.6, 3.3 -1.06
WSB/EiJ f 1.54 0.288   10 0.0909 0.187 1.2, 2.1 -1.08
WSB/EiJ m 2.02 0.355   10 0.112 0.176 1.6, 2.7 -1.29


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 2.61 0.334 3.266 1.954
129S1/SvImJ m 5.07 0.334 5.726 4.414
129X1/SvJ f 3.79 0.334 4.446 3.134
129X1/SvJ m 5.47 0.334 6.126 4.814
A/J f 4.28 0.334 4.936 3.624
A/J m 5.62 0.334 6.276 4.964
AKR/J f 9.68 0.334 10.336 9.024
AKR/J m 9.38 0.334 10.036 8.724
BALB/cJ f 4.4 0.334 5.056 3.744
BALB/cJ m 4.19 0.334 4.846 3.534
BTBR T+ Itpr3tf/J f 3.8111 0.352 4.5026 3.1196
BTBR T+ Itpr3tf/J m 4.23 0.334 4.886 3.574
BUB/BnJ f 3.37 0.334 4.026 2.714
BUB/BnJ m 3.59 0.334 4.246 2.934
C3H/HeJ f 4.78 0.334 5.436 4.124
C3H/HeJ m 6.25 0.334 6.906 5.594
C57BL/6J f 2.6 0.334 3.256 1.944
C57BL/6J m 4.38 0.334 5.036 3.724
C57L/J f 2.87 0.334 3.526 2.214
C57L/J m 4.99 0.334 5.646 4.334
C58/J f 2.69 0.334 3.346 2.034
C58/J m 5.8889 0.352 6.5804 5.1974
CAST/EiJ f 1.63 0.334 2.286 0.974
CAST/EiJ m 1.94 0.334 2.596 1.284
CZECHII/EiJ f 1.6333 0.3049 2.2322 1.0345
CZECHII/EiJ m 1.8833 0.3049 2.4822 1.2845
DBA/2J f 4.49 0.334 5.146 3.834
DBA/2J m 6.25 0.334 6.906 5.594
FVB/NJ f 4.14 0.334 4.796 3.484
FVB/NJ m 3.4 0.334 4.056 2.744
JF1/MsJ f 3.0545 0.3184 3.68 2.4291
JF1/MsJ m 7.45 0.334 8.106 6.794
MOLF/EiJ f 1.37 0.334 2.026 0.714
MOLF/EiJ m 1.7375 0.3734 2.4709 1.0041
MSM/MsJ f 1.4 0.3184 2.0255 0.7745
MSM/MsJ m 1.8222 0.352 2.5137 1.1307
NOD/ShiLtJ f 2.87 0.334 3.526 2.214
NOD/ShiLtJ m 3.78 0.334 4.436 3.124
NZB/BlNJ f 3.63 0.334 4.286 2.974
NZB/BlNJ m 4.0 0.334 4.656 3.344
NZW/LacJ f 6.99 0.334 7.646 6.334
NZW/LacJ m 4.96 0.334 5.616 4.304
PERA/EiJ f 4.93 0.334 5.586 4.274
PERA/EiJ m 3.89 0.334 4.546 3.234
PL/J f 3.15 0.334 3.806 2.494
PL/J m 4.2182 0.3184 4.8436 3.5927
PWK/PhJ f 1.6462 0.2929 2.2215 1.0708
PWK/PhJ m 3.6222 0.352 4.3137 2.9307
SEA/GnJ f 5.6714 0.2822 6.2258 5.117
SEA/GnJ m 7.59 0.334 8.246 6.934
SJL/J f 2.86 0.334 3.516 2.204
SJL/J m 3.58 0.334 4.236 2.924
SM/J f 3.36 0.334 4.016 2.704
SM/J m 4.63 0.334 5.286 3.974
SPRET/EiJ f 2.0222 0.352 2.7137 1.3307
SPRET/EiJ m 3.41 0.334 4.066 2.754
SWR/J f 2.52 0.334 3.176 1.864
SWR/J m 2.45 0.334 3.106 1.794
WSB/EiJ f 1.54 0.334 2.196 0.884
WSB/EiJ m 2.02 0.334 2.676 1.364


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 3.84 0.2361 4.3039 3.3761
129X1/SvJ both 4.63 0.2361 5.0939 4.1661
A/J both 4.95 0.2361 5.4139 4.4861
AKR/J both 9.53 0.2361 9.9939 9.0661
BALB/cJ both 4.295 0.2361 4.7589 3.8311
BTBR T+ Itpr3tf/J both 4.0206 0.2426 4.4971 3.544
BUB/BnJ both 3.48 0.2361 3.9439 3.0161
C3H/HeJ both 5.515 0.2361 5.9789 5.0511
C57BL/6J both 3.49 0.2361 3.9539 3.0261
C57L/J both 3.93 0.2361 4.3939 3.4661
C58/J both 4.2894 0.2426 4.766 3.8129
CAST/EiJ both 1.785 0.2361 2.2489 1.3211
CZECHII/EiJ both 1.7583 0.2156 2.1818 1.3349
DBA/2J both 5.37 0.2361 5.8339 4.9061
FVB/NJ both 3.77 0.2361 4.2339 3.3061
JF1/MsJ both 5.2523 0.2307 5.7055 4.7991
MOLF/EiJ both 1.5537 0.2505 2.0457 1.0618
MSM/MsJ both 1.6111 0.2373 2.0773 1.1449
NOD/ShiLtJ both 3.325 0.2361 3.7889 2.8611
NZB/BlNJ both 3.815 0.2361 4.2789 3.3511
NZW/LacJ both 5.975 0.2361 6.4389 5.5111
PERA/EiJ both 4.41 0.2361 4.8739 3.9461
PL/J both 3.6841 0.2307 4.1373 3.2309
PWK/PhJ both 2.6342 0.229 3.084 2.1844
SEA/GnJ both 6.6307 0.2186 7.0602 6.2013
SJL/J both 3.22 0.2361 3.6839 2.7561
SM/J both 3.995 0.2361 4.4589 3.5311
SPRET/EiJ both 2.7161 0.2426 3.1927 2.2395
SWR/J both 2.485 0.2361 2.9489 2.0211
WSB/EiJ both 1.78 0.2361 2.2439 1.3161




  GWAS USING LINEAR MIXED MODELS