Project measure / variable:   Donahue1   lean_wt

ID, description, units MPD:11510   lean_wt   lean body tissue mass, head excluded   [g]  
Data set, strains Donahue1   inbred w/CC7   30 strains     sex: both     age: 15-16wks
Procedure DXA
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  STRAIN COMPARISON PLOT
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Donahue1 - lean body tissue mass, head excluded



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested30 strains30 strains
Mean of the strain means14.0   g 17.8   g
Median of the strain means14.5   g 18.6   g
SD of the strain means± 3.46 ± 4.04
Coefficient of variation (CV)0.247 0.227
Min–max range of strain means7.53   –   20.7   g 10.1   –   22.9   g
Mean sample size per strain10.2   mice 9.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2255.4335 2255.4335 1535.5646 < 0.0001
strain 29 7937.735 273.715 186.3531 < 0.0001
sex:strain 29 274.7656 9.4747 6.4506 < 0.0001
Residuals 547 803.4322 1.4688


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 13.7 0.964   10 0.305 0.0704 12.0, 14.9 -0.09
129S1/SvImJ m 18.7 1.8   10 0.568 0.0961 17.1, 23.2 0.23
129X1/SvJ f 15.1 1.11   10 0.35 0.0731 13.6, 17.0 0.32
129X1/SvJ m 18.5 1.11   10 0.352 0.0602 17.1, 20.3 0.18
A/J f 14.7 0.953   10 0.301 0.0648 13.3, 16.5 0.2
A/J m 17.6 1.4   10 0.443 0.0796 15.8, 19.6 -0.04
AKR/J f 20.7 1.45   10 0.458 0.0701 18.6, 23.2 1.93
AKR/J m 22.9 1.04   10 0.33 0.0456 21.0, 24.7 1.27
BALB/cJ f 15.1 1.14   10 0.36 0.0753 12.6, 16.5 0.32
BALB/cJ m 20.9 0.826   10 0.261 0.0395 19.2, 22.3 0.77
BTBR T+ Itpr3tf/J f 20.1 1.21   9 0.402 0.06 18.4, 21.7 1.76
BTBR T+ Itpr3tf/J m 22.8 1.75   10 0.554 0.077 20.1, 26.1 1.24
BUB/BnJ f 18.5 1.22   10 0.386 0.0659 17.0, 20.8 1.3
BUB/BnJ m 21.5 1.83   10 0.577 0.0847 18.2, 23.5 0.92
C3H/HeJ f 15.6 1.07   10 0.338 0.0687 13.7, 17.4 0.46
C3H/HeJ m 20.0 1.68   10 0.532 0.0841 16.8, 21.8 0.55
C57BL/6J f 14.3 1.21   10 0.382 0.0843 12.6, 16.2 0.09
C57BL/6J m 21.6 0.714   10 0.226 0.033 20.6, 22.7 0.95
C57L/J f 15.3 0.735   10 0.232 0.0479 14.4, 16.4 0.37
C57L/J m 20.4 1.19   10 0.376 0.0584 18.6, 22.3 0.65
C58/J f 16.8 1.66   10 0.525 0.0988 13.9, 19.2 0.81
C58/J m 20.7 1.0   9 0.334 0.0485 18.6, 22.1 0.72
CAST/EiJ f 10.0 0.53   10 0.167 0.0527 9.4, 11.1 -1.16
CAST/EiJ m 11.6 0.95   10 0.3 0.082 10.1, 13.0 -1.53
CZECHII/EiJ f 8.84 0.649   12 0.187 0.0734 7.8, 10.4 -1.49
CZECHII/EiJ m 11.5 1.32   12 0.382 0.115 8.8, 13.3 -1.55
DBA/2J f 15.2 0.814   10 0.257 0.0534 14.3, 16.7 0.35
DBA/2J m 19.5 1.16   10 0.367 0.0595 17.6, 20.8 0.43
FVB/NJ f 15.6 0.594   10 0.188 0.0381 14.8, 16.5 0.46
FVB/NJ m 19.8 1.06   10 0.335 0.0534 18.5, 21.4 0.5
JF1/MsJ f 10.8 0.626   11 0.189 0.0578 10.2, 12.2 -0.93
JF1/MsJ m 12.9 0.698   10 0.221 0.0539 11.3, 13.9 -1.21
MOLF/EiJ f 9.01 0.543   10 0.172 0.0602 8.4, 10.0 -1.44
MOLF/EiJ m 10.9 0.727   8 0.257 0.0665 10.2, 12.3 -1.7
MSM/MsJ f 7.53 0.704   11 0.212 0.0936 6.7, 8.6 -1.87
MSM/MsJ m 10.1 0.669   9 0.223 0.066 9.0, 10.9 -1.9
NOD/ShiLtJ f 17.9 0.926   10 0.293 0.0516 16.7, 19.2 1.13
NOD/ShiLtJ m 21.9 1.97   10 0.624 0.0899 17.6, 25.0 1.02
NZB/BlNJ f 16.6 0.982   10 0.311 0.0591 14.8, 18.1 0.75
NZB/BlNJ m 20.6 1.85   10 0.586 0.0901 17.4, 24.0 0.7
NZW/LacJ f 17.6 1.7   10 0.538 0.0969 13.7, 19.5 1.04
NZW/LacJ m 22.0 1.97   10 0.624 0.0897 20.1, 26.4 1.04
PERA/EiJ f 13.2 0.646   10 0.204 0.049 12.2, 14.5 -0.23
PERA/EiJ m 17.4 2.03   10 0.641 0.116 15.2, 22.0 -0.09
PL/J f 12.8 0.736   10 0.233 0.0575 11.7, 14.3 -0.35
PL/J m 17.1 1.65   11 0.497 0.0967 15.2, 20.6 -0.17
PWK/PhJ f 10.6 0.971   13 0.269 0.0915 8.9, 12.1 -0.98
PWK/PhJ m 14.5 1.32   9 0.44 0.0912 12.2, 16.4 -0.81
SEA/GnJ f 16.8 1.84   14 0.493 0.109 14.2, 19.1 0.81
SEA/GnJ m 20.6 1.95   10 0.616 0.0947 17.3, 22.9 0.7
SJL/J f 13.3 0.971   10 0.307 0.073 12.3, 15.5 -0.2
SJL/J m 18.6 1.22   10 0.385 0.0656 16.6, 20.8 0.2
SM/J f 12.0 1.11   10 0.352 0.0924 10.3, 13.9 -0.58
SM/J m 18.4 1.08   10 0.342 0.0589 16.1, 19.6 0.15
SPRET/EiJ f 8.79 0.631   9 0.21 0.0718 7.8, 9.8 -1.51
SPRET/EiJ m 11.1 1.02   10 0.322 0.0918 8.9, 12.7 -1.65
SWR/J f 13.9 0.758   10 0.24 0.0545 13.0, 15.1 -0.03
SWR/J m 17.8 0.784   10 0.248 0.044 16.6, 19.4 0.0
WSB/EiJ f 9.71 0.677   10 0.214 0.0698 8.2, 10.7 -1.24
WSB/EiJ m 11.5 0.767   10 0.243 0.0669 9.5, 12.1 -1.55


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 13.69 0.3832 14.4428 12.9372
129S1/SvImJ m 18.71 0.3832 19.4628 17.9572
129X1/SvJ f 15.14 0.3832 15.8928 14.3872
129X1/SvJ m 18.51 0.3832 19.2628 17.7572
A/J f 14.72 0.3832 15.4728 13.9672
A/J m 17.59 0.3832 18.3428 16.8372
AKR/J f 20.66 0.3832 21.4128 19.9072
AKR/J m 22.91 0.3832 23.6628 22.1572
BALB/cJ f 15.11 0.3832 15.8628 14.3572
BALB/cJ m 20.9 0.3832 21.6528 20.1472
BTBR T+ Itpr3tf/J f 20.1111 0.404 20.9047 19.3176
BTBR T+ Itpr3tf/J m 22.78 0.3832 23.5328 22.0272
BUB/BnJ f 18.54 0.3832 19.2928 17.7872
BUB/BnJ m 21.54 0.3832 22.2928 20.7872
C3H/HeJ f 15.58 0.3832 16.3328 14.8272
C3H/HeJ m 20.0 0.3832 20.7528 19.2472
C57BL/6J f 14.33 0.3832 15.0828 13.5772
C57BL/6J m 21.61 0.3832 22.3628 20.8572
C57L/J f 15.34 0.3832 16.0928 14.5872
C57L/J m 20.36 0.3832 21.1128 19.6072
C58/J f 16.8 0.3832 17.5528 16.0472
C58/J m 20.6556 0.404 21.4491 19.862
CAST/EiJ f 10.04 0.3832 10.7928 9.2872
CAST/EiJ m 11.58 0.3832 12.3328 10.8272
CZECHII/EiJ f 8.8417 0.3499 9.5289 8.1544
CZECHII/EiJ m 11.525 0.3499 12.2122 10.8378
DBA/2J f 15.25 0.3832 16.0028 14.4972
DBA/2J m 19.51 0.3832 20.2628 18.7572
FVB/NJ f 15.58 0.3832 16.3328 14.8272
FVB/NJ m 19.8 0.3832 20.5528 19.0472
JF1/MsJ f 10.8273 0.3654 11.5451 10.1095
JF1/MsJ m 12.95 0.3832 13.7028 12.1972
MOLF/EiJ f 9.01 0.3832 9.7628 8.2572
MOLF/EiJ m 10.9375 0.4285 11.7792 10.0958
MSM/MsJ f 7.5273 0.3654 8.2451 6.8095
MSM/MsJ m 10.1444 0.404 10.938 9.3509
NOD/ShiLtJ f 17.95 0.3832 18.7028 17.1972
NOD/ShiLtJ m 21.94 0.3832 22.6928 21.1872
NZB/BlNJ f 16.63 0.3832 17.3828 15.8772
NZB/BlNJ m 20.56 0.3832 21.3128 19.8072
NZW/LacJ f 17.57 0.3832 18.3228 16.8172
NZW/LacJ m 21.99 0.3832 22.7428 21.2372
PERA/EiJ f 13.18 0.3832 13.9328 12.4272
PERA/EiJ m 17.42 0.3832 18.1728 16.6672
PL/J f 12.8 0.3832 13.5528 12.0472
PL/J m 17.0636 0.3654 17.7814 16.3459
PWK/PhJ f 10.6077 0.3361 11.268 9.9474
PWK/PhJ m 14.4667 0.404 15.2602 13.6731
SEA/GnJ f 16.8429 0.3239 17.4791 16.2066
SEA/GnJ m 20.56 0.3832 21.3128 19.8072
SJL/J f 13.3 0.3832 14.0528 12.5472
SJL/J m 18.57 0.3832 19.3228 17.8172
SM/J f 12.03 0.3832 12.7828 11.2772
SM/J m 18.37 0.3832 19.1228 17.6172
SPRET/EiJ f 8.7889 0.404 9.5824 7.9953
SPRET/EiJ m 11.08 0.3832 11.8328 10.3272
SWR/J f 13.91 0.3832 14.6628 13.1572
SWR/J m 17.81 0.3832 18.5628 17.0572
WSB/EiJ f 9.71 0.3832 10.4628 8.9572
WSB/EiJ m 11.47 0.3832 12.2228 10.7172


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 16.2 0.271 16.7323 15.6677
129X1/SvJ both 16.825 0.271 17.3573 16.2927
A/J both 16.155 0.271 16.6873 15.6227
AKR/J both 21.785 0.271 22.3173 21.2527
BALB/cJ both 18.005 0.271 18.5373 17.4727
BTBR T+ Itpr3tf/J both 21.4456 0.2784 21.9925 20.8986
BUB/BnJ both 20.04 0.271 20.5723 19.5077
C3H/HeJ both 17.79 0.271 18.3223 17.2577
C57BL/6J both 17.97 0.271 18.5023 17.4377
C57L/J both 17.85 0.271 18.3823 17.3177
C58/J both 18.7278 0.2784 19.2747 18.1809
CAST/EiJ both 10.81 0.271 11.3423 10.2777
CZECHII/EiJ both 10.1833 0.2474 10.6693 9.6974
DBA/2J both 17.38 0.271 17.9123 16.8477
FVB/NJ both 17.69 0.271 18.2223 17.1577
JF1/MsJ both 11.8886 0.2648 12.4087 11.3686
MOLF/EiJ both 9.9737 0.2874 10.5384 9.4091
MSM/MsJ both 8.8359 0.2724 9.3709 8.3009
NOD/ShiLtJ both 19.945 0.271 20.4773 19.4127
NZB/BlNJ both 18.595 0.271 19.1273 18.0627
NZW/LacJ both 19.78 0.271 20.3123 19.2477
PERA/EiJ both 15.3 0.271 15.8323 14.7677
PL/J both 14.9318 0.2648 15.4519 14.4117
PWK/PhJ both 12.5372 0.2628 13.0533 12.021
SEA/GnJ both 18.7014 0.2509 19.1943 18.2086
SJL/J both 15.935 0.271 16.4673 15.4027
SM/J both 15.2 0.271 15.7323 14.6677
SPRET/EiJ both 9.9344 0.2784 10.4814 9.3875
SWR/J both 15.86 0.271 16.3923 15.3277
WSB/EiJ both 10.59 0.271 11.1223 10.0577




  GWAS USING LINEAR MIXED MODELS