Project measure / variable:   Auwerx2   hdl_CD

ID, description, units MPD:114687   hdl_CD   plasma HDL amount   [mmol/L]  CD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 21wks
Procedure lipid profile
Ontology mappings

  STRAIN COMPARISON PLOT
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Auwerx2 - plasma HDL amount CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means2.2165   mmol/L 2.7945   mmol/L
Median of the strain means1.9792   mmol/L 2.442   mmol/L
SD of the strain means± 1.0494 ± 1.0819
Coefficient of variation (CV)0.4735 0.3871
Min–max range of strain means1.168   –   4.5815   mmol/L 1.4177   –   4.898   mmol/L
Mean sample size per strain4.4   mice 4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 8.4575 8.4575 64.4407 < 0.0001
strain 7 63.3346 9.0478 68.9382 < 0.0001
sex:strain 7 4.8515 0.6931 5.2807 < 0.0001
Residuals 63 8.2684 0.1312


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 3.0678 0.21116   5 0.09443 0.0688 2.754, 3.281 0.81
129S1/SvImJ m 4.128 0.59641   5 0.26672 0.1445 3.542, 5.094 1.23
A/J f 1.7294 0.19617   5 0.08773 0.1134 1.456, 2.006 -0.46
A/J m 2.131 0.14658   5 0.06555 0.0688 1.946, 2.356 -0.61
C57BL/6J f 1.9792 0.17739   5 0.07933 0.0896 1.801, 2.185 -0.23
C57BL/6J m 2.7832 0.36741   5 0.16431 0.132 2.385, 3.227 -0.01
CAST/EiJ f 1.168 0.0   1   0.0 0.0 1.168, 1.168 -1.0
CAST/EiJ m 1.4177 0.41635   3 0.24038 0.2937 1.16, 1.898 -1.27
DBA/2J f 1.3386 0.30051   5 0.13439 0.2245 1.063, 1.715 -0.84
DBA/2J m 2.93 0.2411   5 0.10782 0.0823 2.656, 3.205 0.13
NOD/ShiLtJ f 2.0941 0.21756   7 0.08223 0.1039 1.857, 2.469 -0.12
NOD/ShiLtJ m 2.442 0.35612   5 0.15926 0.1458 2.109, 3.004 -0.33
NZO/HlLtJ f 4.5815 0.48263   4 0.24131 0.1053 3.891, 4.986 2.25
NZO/HlLtJ m 4.898 0.71614   5 0.32027 0.1462 3.973, 5.803 1.94
PWK/PhJ f 2.3234 0.25843   5 0.11557 0.1112 2.156, 2.78 0.1
PWK/PhJ m 2.2018 0.15301   5 0.06843 0.0695 1.944, 2.332 -0.55
WSB/EiJ f 1.6663 0.29781   3 0.17194 0.1787 1.331, 1.9 -0.52
WSB/EiJ m 2.2192 0.52158   5 0.23326 0.235 1.505, 2.786 -0.53


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 3.0678 0.1620155403 3.3915622228 2.7440377772
129S1/SvImJ m 4.128 0.1620155403 4.4517622228 3.8042377772
A/J f 1.7294 0.1620155403 2.0531622228 1.4056377772
A/J m 2.131 0.1620155403 2.4547622228 1.8072377772
C57BL/6J f 1.9792 0.1620155403 2.3029622228 1.6554377772
C57BL/6J m 2.7832 0.1620155403 3.1069622228 2.4594377772
DBA/2J f 1.3386 0.1620155403 1.6623622228 1.0148377772
DBA/2J m 2.93 0.1620155403 3.2537622228 2.6062377772
NOD/ShiLtJ f 2.0941428571 0.1369281233 2.3677718773 1.820513837
NOD/ShiLtJ m 2.442 0.1620155403 2.7657622228 2.1182377772
NZO/HlLtJ f 4.5815 0.1811388808 4.9434771694 4.2195228306
NZO/HlLtJ m 4.898 0.1620155403 5.2217622228 4.5742377772
PWK/PhJ f 2.3234 0.1620155403 2.6471622228 1.9996377772
PWK/PhJ m 2.2018 0.1620155403 2.5255622228 1.8780377772
WSB/EiJ f 1.6663333333 0.2091611632 2.0843085657 1.248358101
WSB/EiJ m 2.2192 0.1620155403 2.5429622228 1.8954377772


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 3.5979 0.1145622872 3.8268344632 3.3689655368
A/J both 1.9302 0.1145622872 2.1591344632 1.7012655368
C57BL/6J both 2.3812 0.1145622872 2.6101344632 2.1522655368
DBA/2J both 2.1343 0.1145622872 2.3632344632 1.9053655368
NOD/ShiLtJ both 2.2680714286 0.1060640682 2.4800235562 2.056119301
NZO/HlLtJ both 4.73975 0.1215116553 4.9825716671 4.4969283329
PWK/PhJ both 2.2626 0.1145622872 2.4915344632 2.0336655368
WSB/EiJ both 1.9427666667 0.1322851347 2.2071174146 1.6784159187




  GWAS USING LINEAR MIXED MODELS