Project measure / variable:   Auwerx2   subcut_adip_wt_HFD

ID, description, units MPD:114668   subcut_adip_wt_HFD   subcutaneous adipose tissue weight   [g]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 21wks
Procedure organ weights
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  STRAIN COMPARISON PLOT
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Auwerx2 - subcutaneous adipose tissue weight HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means1.1332   g 1.4997   g
Median of the strain means0.72693   g 1.2402   g
SD of the strain means± 1.4803 ± 1.468
Coefficient of variation (CV)1.3063 0.9788
Min–max range of strain means0.071   –   4.8536   g 0.10808   –   4.8354   g
Mean sample size per strain4.4   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3.0548 3.0548 18.4533 < 0.0001
strain 7 25.7987 3.6855 22.2632 < 0.0001
sex:strain 7 2.9712 0.4245 2.564 0.0239
Residuals 52 8.6083 0.1655


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.4277 0.1097   5 0.04906 0.2565 0.3468, 0.6173 -0.48
129S1/SvImJ m 1.2402 0.01563   2   0.01105 0.0126 1.2291, 1.2512 -0.18
A/J f 0.39287 0.19064   4 0.09532 0.4852 0.2057, 0.6581 -0.5
A/J m 0.52058 0.08598   5 0.03845 0.1652 0.448, 0.6172 -0.67
C57BL/6J f 0.90053 0.50115   3 0.28934 0.5565 0.4745, 1.4527 -0.16
C57BL/6J m 2.247 0.61729   4 0.30864 0.2747 1.4598, 2.7898 0.51
CAST/EiJ f 0.07164 0.00984444   5 0.00440257 0.1374 0.0594, 0.082 -0.72
CAST/EiJ m 0.2725 0.14538   2   0.1028 0.5335 0.1697, 0.3753 -0.84
DBA/2J f 1.5332 0.86834   5 0.38833 0.5664 0.1796, 2.3844 0.27
DBA/2J m 2.0382 0.72328   5 0.32346 0.3549 1.1172, 3.0322 0.37
NOD/ShiLtJ f 0.72693 0.23276   6 0.09503 0.3202 0.5353, 1.187 -0.27
NOD/ShiLtJ m 0.6161 0.07179   5 0.0321 0.1165 0.5381, 0.6924 -0.6
NZO/HlLtJ f 4.8536 0.45215   5 0.20221 0.0932 4.35, 5.5053 2.51
NZO/HlLtJ m 4.8354 0.0   1   0.0 0.0 4.8354, 4.8354 2.27
PWK/PhJ f 1.2213 0.25595   4 0.12798 0.2096 1.0414, 1.5991 0.06
PWK/PhJ m 1.6194 0.53625   5 0.23982 0.3311 0.8419, 2.1016 0.08
WSB/EiJ f 0.071 0.04274   3 0.02468 0.602 0.0354, 0.1184 -0.72
WSB/EiJ m 0.10808 0.03066   5 0.01371 0.2837 0.0763, 0.1528 -0.95


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.4277 0.1819582604 0.7928259619 0.0625740381
129S1/SvImJ m 1.24015 0.287701271 1.8174648363 0.6628351637
A/J f 0.392875 0.2034355197 0.8010982356 -0.0153482356
A/J m 0.52058 0.1819582604 0.8857059619 0.1554540381
C57BL/6J f 0.9005333333 0.2349071041 1.3719089233 0.4291577434
C57BL/6J m 2.247 0.2034355197 2.6552232356 1.8387767644
CAST/EiJ f 0.07164 0.1819582604 0.4367659619 -0.2934859619
CAST/EiJ m 0.2725 0.287701271 0.8498148363 -0.3048148363
DBA/2J f 1.53316 0.1819582604 1.8982859619 1.1680340381
DBA/2J m 2.03816 0.1819582604 2.4032859619 1.6730340381
NOD/ShiLtJ f 0.7269333333 0.1661044063 1.0602462095 0.3936204572
NOD/ShiLtJ m 0.6161 0.1819582604 0.9812259619 0.2509740381
PWK/PhJ f 1.221325 0.2034355197 1.6295482356 0.8131017644
PWK/PhJ m 1.61942 0.1819582604 1.9845459619 1.2542940381
WSB/EiJ f 0.071 0.2349071041 0.54237559 -0.40037559
WSB/EiJ m 0.10808 0.1819582604 0.4732059619 -0.2570459619


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.833925 0.1702063673 1.1754690632 0.4923809368
A/J both 0.4567275 0.1364686953 0.7305719715 0.1828830285
C57BL/6J both 1.5737666667 0.1553764447 1.885552313 1.2619810204
CAST/EiJ both 0.17207 0.1702063673 0.5136140632 -0.1694740632
DBA/2J both 1.78566 0.1286639198 2.0438430437 1.5274769563
NOD/ShiLtJ both 0.6715166667 0.1231863246 0.9187081114 0.4243252219
PWK/PhJ both 1.4203725 0.1364686953 1.6942169715 1.1465280285
WSB/EiJ both 0.08954 0.1485682975 0.3876640995 -0.2085840995




  GWAS USING LINEAR MIXED MODELS