Project measure / variable:   Auwerx2   kidney_wt_CD

ID, description, units MPD:114659   kidney_wt_CD   kidney weight (both)   [g]  CD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 21wks
Procedure organ weights
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  STRAIN COMPARISON PLOT
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Auwerx2 - kidney weight (both) CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means0.24697   g 0.35835   g
Median of the strain means0.24342   g 0.30414   g
SD of the strain means± 0.08512 ± 0.14619
Coefficient of variation (CV)0.3447 0.4079
Min–max range of strain means0.1439   –   0.43505   g 0.20693   –   0.59386   g
Mean sample size per strain4.4   mice 4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.2743 0.2743 361.3212 < 0.0001
strain 7 0.7756 0.1108 145.9536 < 0.0001
sex:strain 7 0.132 0.0189 24.8486 < 0.0001
Residuals 63 0.0478 0.0008


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.25336 0.01522   5 0.00680842 0.0601 0.23, 0.2707 0.08
129S1/SvImJ m 0.31908 0.0292   5 0.01306 0.0915 0.2733, 0.3452 -0.27
A/J f 0.24342 0.01863   5 0.00833375 0.0766 0.2209, 0.2701 -0.04
A/J m 0.26886 0.01495   5 0.00668391 0.0556 0.2536, 0.2917 -0.61
C57BL/6J f 0.2274 0.01357   5 0.0060705 0.0597 0.2095, 0.2414 -0.23
C57BL/6J m 0.30414 0.02228   5 0.00996457 0.0733 0.2744, 0.3325 -0.37
CAST/EiJ f 0.1439 0.0   1   0.0 0.0 0.1439, 0.1439 -1.21
CAST/EiJ m 0.20693 0.00611746   3 0.00353192 0.0296 0.2011, 0.2133 -1.04
DBA/2J f 0.30346 0.01684   5 0.00753018 0.0555 0.2821, 0.327 0.66
DBA/2J m 0.59386 0.05004   5 0.02238 0.0843 0.5361, 0.6418 1.61
NOD/ShiLtJ f 0.244 0.01998   7 0.00754996 0.0819 0.224, 0.2835 -0.03
NOD/ShiLtJ m 0.42962 0.02291   5 0.01024 0.0533 0.3968, 0.452 0.49
NZO/HlLtJ f 0.43505 0.02644   4 0.01322 0.0608 0.4111, 0.4693 2.21
NZO/HlLtJ m 0.58738 0.05567   5 0.0249 0.0948 0.5144, 0.6601 1.57
PWK/PhJ f 0.2074 0.01977   5 0.00883997 0.0953 0.1831, 0.2329 -0.46
PWK/PhJ m 0.29138 0.00920581   5 0.00411696 0.0316 0.2827, 0.307 -0.46
WSB/EiJ f 0.16473 0.00765528   3 0.00441978 0.0465 0.1583, 0.1732 -0.97
WSB/EiJ m 0.22394 0.03976   5 0.01778 0.1776 0.1649, 0.2533 -0.92


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.25336 0.0123217357 0.277983024 0.228736976
129S1/SvImJ m 0.31908 0.0123217357 0.343703024 0.294456976
A/J f 0.24342 0.0123217357 0.268043024 0.218796976
A/J m 0.26886 0.0123217357 0.293483024 0.244236976
C57BL/6J f 0.2274 0.0123217357 0.252023024 0.202776976
C57BL/6J m 0.30414 0.0123217357 0.328763024 0.279516976
DBA/2J f 0.30346 0.0123217357 0.328083024 0.278836976
DBA/2J m 0.59386 0.0123217357 0.618483024 0.569236976
NOD/ShiLtJ f 0.244 0.0104137673 0.2648102535 0.2231897465
NOD/ShiLtJ m 0.42962 0.0123217357 0.454243024 0.404996976
NZO/HlLtJ f 0.43505 0.0137761193 0.4625793777 0.4075206223
NZO/HlLtJ m 0.58738 0.0123217357 0.612003024 0.562756976
PWK/PhJ f 0.2074 0.0123217357 0.232023024 0.182776976
PWK/PhJ m 0.29138 0.0123217357 0.316003024 0.266756976
WSB/EiJ f 0.1647333333 0.0159072924 0.1965215206 0.1329451461
WSB/EiJ m 0.22394 0.0123217357 0.248563024 0.199316976


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.28622 0.0087127829 0.3036311072 0.2688088928
A/J both 0.25614 0.0087127829 0.2735511072 0.2387288928
C57BL/6J both 0.26577 0.0087127829 0.2831811072 0.2483588928
DBA/2J both 0.44866 0.0087127829 0.4660711072 0.4312488928
NOD/ShiLtJ both 0.33681 0.0080664695 0.352929553 0.320690447
NZO/HlLtJ both 0.511215 0.0092413018 0.529682268 0.492747732
PWK/PhJ both 0.24939 0.0087127829 0.2668011072 0.2319788928
WSB/EiJ both 0.1943366667 0.0100606551 0.2144412816 0.1742320518




  GWAS USING LINEAR MIXED MODELS