Project measure / variable:   Auwerx2   vo2_max_treadmill_CD

ID, description, units MPD:114641   vo2_max_treadmill_CD   maximum oxygen consumption, treadmill test   [ratio]  CD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 19wks
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  STRAIN COMPARISON PLOT
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Auwerx2 - maximum oxygen consumption, treadmill test CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means139.3   ratio 127.4   ratio
Median of the strain means140.1   ratio 123.9   ratio
SD of the strain means± 27.518 ± 24.459
Coefficient of variation (CV)0.1976 0.1919
Min–max range of strain means96.87   –   180.1   ratio 93.21   –   169.1   ratio
Mean sample size per strain4.2   mice 4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1713.1418 1713.1418 8.7184 0.0045
strain 7 41940.0842 5991.4406 30.491 < 0.0001
sex:strain 7 1713.0156 244.7165 1.2454 0.2932
Residuals 59 11593.4022 196.4983


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 121.3 20.324   5 9.089 0.1675 98.24, 147.5 -0.65
129S1/SvImJ m 111.3 8.9134   5 3.9862 0.0801 106.0, 126.6 -0.66
A/J f 96.87 3.2657   4 1.6329 0.0337 93.29, 100.8 -1.54
A/J m 93.21 7.1086   3 4.1042 0.0763 88.64, 101.4 -1.4
C57BL/6J f 151.9 10.097   5 4.5157 0.0665 135.8, 163.1 0.46
C57BL/6J m 123.9 6.1528   5 2.7516 0.0497 117.1, 132.2 -0.14
CAST/EiJ f 153.4 0.0   1   0.0 0.0 153.4, 153.4 0.51
CAST/EiJ m 144.3 9.9232   3 5.7292 0.0688 135.4, 155.0 0.69
DBA/2J f 140.1 17.84   5 7.9781 0.1274 123.5, 168.1 0.03
DBA/2J m 140.5 16.626   5 7.4354 0.1183 114.5, 156.4 0.53
NOD/ShiLtJ f 124.1 9.4141   6 3.8433 0.0758 110.2, 138.6 -0.55
NOD/ShiLtJ m 117.8 5.217   5 2.3331 0.0443 112.4, 125.5 -0.39
NZO/HlLtJ f 114.2 8.5841   4 4.292 0.0752 104.1, 122.6 -0.91
NZO/HlLtJ m 100.8 7.9636   5 3.5614 0.079 94.26, 114.2 -1.09
PWK/PhJ f 171.7 18.775   5 8.3965 0.1093 152.1, 193.9 1.18
PWK/PhJ m 146.1 9.9178   5 4.4354 0.0679 136.9, 160.1 0.76
WSB/EiJ f 180.1 13.572   3 7.8359 0.0753 164.6, 189.7 1.48
WSB/EiJ m 169.1 28.956   5 12.949 0.1712 141.6, 215.3 1.7


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 121.308 6.2689447656 133.8521295015 108.7638704985
129S1/SvImJ m 111.34 6.2689447656 123.8841295015 98.7958704985
A/J f 96.87 7.0088933216 110.894763142 82.845236858
A/J m 93.21 8.0931728919 109.4044015507 77.0155984493
C57BL/6J f 151.88 6.2689447656 164.4241295015 139.3358704985
C57BL/6J m 123.88 6.2689447656 136.4241295015 111.3358704985
DBA/2J f 140.06 6.2689447656 152.6041295015 127.5158704985
DBA/2J m 140.5 6.2689447656 153.0441295015 127.9558704985
NOD/ShiLtJ f 124.1166666667 5.7227374332 135.5678378204 112.6654955129
NOD/ShiLtJ m 117.82 6.2689447656 130.3641295015 105.2758704985
NZO/HlLtJ f 114.2 7.0088933216 128.224763142 100.175236858
NZO/HlLtJ m 100.846 6.2689447656 113.3901295015 88.3018704985
PWK/PhJ f 171.72 6.2689447656 184.2641295015 159.1758704985
PWK/PhJ m 146.06 6.2689447656 158.6041295015 133.5158704985
WSB/EiJ f 180.1333333333 8.0931728919 196.327734884 163.9389317826
WSB/EiJ m 169.14 6.2689447656 181.6841295015 156.5958704985


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 116.324 4.4328133547 125.1940390346 107.4539609654
A/J both 95.04 5.3531306973 105.7515897837 84.3284102163
C57BL/6J both 137.88 4.4328133547 146.7500390346 129.0099609654
DBA/2J both 140.28 4.4328133547 149.1500390346 131.4099609654
NOD/ShiLtJ both 120.9683333333 4.2440956694 129.4607491519 112.4759175147
NZO/HlLtJ both 107.523 4.7017085742 116.9310971261 98.1149028739
PWK/PhJ both 158.89 4.4328133547 167.7600390346 150.0199609654
WSB/EiJ both 174.6366666667 5.1185719672 184.8789055154 164.394427818




  GWAS USING LINEAR MIXED MODELS