Project measure / variable:   Auwerx2   bw_treadmill_HFD

ID, description, units MPD:114640   bw_treadmill_HFD   body weight, treadmill test   [g]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 19wks
Procedure body weight
Ontology mappings

  STRAIN COMPARISON PLOT
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Auwerx2 - body weight, treadmill test HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means30.55   g 36.049   g
Median of the strain means24.185   g 34.504   g
SD of the strain means± 19.457 ± 17.882
Coefficient of variation (CV)0.6369 0.496
Min–max range of strain means13.436   –   78.0   g 16.375   –   75.4   g
Mean sample size per strain4.4   mice 3.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 607.6684 607.6684 101.5166 < 0.0001
strain 7 4629.9328 661.419 110.4962 < 0.0001
sex:strain 7 428.8511 61.2644 10.2348 < 0.0001
Residuals 50 299.295 5.9859


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 23.336 0.88223   5 0.39455 0.0378 22.28, 24.72 -0.37
129S1/SvImJ m 34.545 1.2799   2   0.905 0.037 33.64, 35.45 -0.08
A/J f 23.295 2.3047   4 1.1523 0.0989 21.37, 26.61 -0.37
A/J m 28.484 0.99505   5 0.445 0.0349 26.94, 29.55 -0.42
C57BL/6J f 28.477 3.3916   3 1.9581 0.1191 26.25, 32.38 -0.11
C57BL/6J m 47.867 0.75831   3 0.43781 0.0158 47.04, 48.53 0.66
CAST/EiJ f 13.436 0.99007   5 0.44277 0.0737 12.45, 15.05 -0.88
CAST/EiJ m 18.5 1.5556   2   1.1 0.0841 17.4, 19.6 -0.98
DBA/2J f 36.74 4.2379   5 1.8953 0.1153 31.61, 41.86 0.32
DBA/2J m 41.712 3.4119   5 1.5259 0.0818 38.6, 47.55 0.32
NOD/ShiLtJ f 33.833 3.186   6 1.3007 0.0942 31.3, 39.4 0.17
NOD/ShiLtJ m 34.504 1.5545   5 0.69519 0.0451 33.02, 36.86 -0.09
NZO/HlLtJ f 78.0 2.493   5 1.1149 0.032 75.7, 81.0 2.44
NZO/HlLtJ m 75.4 0.0   1   0.0 0.0 75.4, 75.4 2.2
PWK/PhJ f 24.185 1.5157   4 0.75785 0.0627 22.6, 26.25 -0.33
PWK/PhJ m 27.056 3.7835   5 1.692 0.1398 22.72, 30.91 -0.5
WSB/EiJ f 13.647 0.1193   3 0.06888 0.0087 13.51, 13.73 -0.87
WSB/EiJ m 16.375 0.61847   4 0.30923 0.0378 15.6, 17.1 -1.1


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 23.336 1.0941571429 25.5336792994 21.1383207006
129S1/SvImJ m 34.545 1.7300143448 38.0198360764 31.0701639236
A/J f 23.295 1.2233048748 25.7520801531 20.8379198469
A/J m 28.484 1.0941571429 30.6816792994 26.2863207006
C57BL/6J f 28.4766666667 1.4125507975 31.3138584423 25.639474891
C57BL/6J m 47.8666666667 1.4125507975 50.7038584423 45.029474891
CAST/EiJ f 13.436 1.0941571429 15.6336792994 11.2383207006
CAST/EiJ m 18.5 1.7300143448 21.9748360764 15.0251639236
DBA/2J f 36.74 1.0941571429 38.9376792994 34.5423207006
DBA/2J m 41.712 1.0941571429 43.9096792994 39.5143207006
NOD/ShiLtJ f 33.8333333333 0.9988242477 35.8395308774 31.8271357892
NOD/ShiLtJ m 34.504 1.0941571429 36.7016792994 32.3063207006
PWK/PhJ f 24.185 1.2233048748 26.6420801531 21.7279198469
PWK/PhJ m 27.056 1.0941571429 29.2536792994 24.8583207006
WSB/EiJ f 13.6466666667 1.4125507975 16.4838584423 10.809474891
WSB/EiJ m 16.375 1.2233048748 18.8320801531 13.9179198469


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 28.9405 1.023490289 30.9962407461 26.8847592539
A/J both 25.8895 0.8206178572 27.5377594746 24.2412405254
C57BL/6J both 38.1716666667 0.9988242477 40.1778642108 36.1654691226
CAST/EiJ both 15.968 1.023490289 18.0237407461 13.9122592539
DBA/2J both 39.226 0.7736859354 40.7799939355 37.6720060645
NOD/ShiLtJ both 34.1686666667 0.7407478875 35.6565025858 32.6808307475
PWK/PhJ both 25.6205 0.8206178572 27.2687594746 23.9722405254
WSB/EiJ both 15.0108333333 0.9343145311 16.8874592984 13.1342073683




  GWAS USING LINEAR MIXED MODELS