Project measure / variable:   Auwerx2   bw_treadmill_CD

ID, description, units MPD:114639   bw_treadmill_CD   body weight, treadmill test   [g]  CD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 19wks
Procedure body weight
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  STRAIN COMPARISON PLOT
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Auwerx2 - body weight, treadmill test CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means23.885   g 28.632   g
Median of the strain means22.182   g 27.13   g
SD of the strain means± 13.107 ± 11.846
Coefficient of variation (CV)0.5488 0.4137
Min–max range of strain means11.853   –   56.52   g 14.844   –   55.64   g
Mean sample size per strain4.2   mice 4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 508.1211 508.1211 68.9925 < 0.0001
strain 7 9427.5035 1346.7862 182.8662 < 0.0001
sex:strain 7 175.0279 25.004 3.395 0.0041
Residuals 59 434.5276 7.3649


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 22.182 0.54965   5 0.24581 0.0248 21.28, 22.68 -0.13
129S1/SvImJ m 26.502 1.3244   5 0.59228 0.05 25.07, 27.97 -0.18
A/J f 24.043 1.4433   4 0.72165 0.06 22.88, 26.15 0.01
A/J m 27.13 1.856   3 1.0716 0.0684 25.96, 29.27 -0.13
C57BL/6J f 21.616 0.6303   5 0.28188 0.0292 20.82, 22.42 -0.17
C57BL/6J m 30.274 2.9782   5 1.3319 0.0984 25.45, 32.7 0.14
CAST/EiJ f 13.03 0.0   1   0.0 0.0 13.03, 13.03 -0.83
CAST/EiJ m 16.247 0.3139   3 0.18123 0.0193 16.0, 16.6 -1.05
DBA/2J f 23.474 1.6595   5 0.74214 0.0707 21.42, 25.95 -0.03
DBA/2J m 32.67 1.5891   5 0.71068 0.0486 30.63, 35.08 0.34
NOD/ShiLtJ f 24.533 0.78762   6 0.32154 0.0321 23.3, 25.35 0.05
NOD/ShiLtJ m 30.324 0.93318   5 0.41733 0.0308 29.56, 31.89 0.14
NZO/HlLtJ f 56.52 3.6619   4 1.8309 0.0648 54.2, 61.9 2.49
NZO/HlLtJ m 55.64 8.3293   5 3.725 0.1497 42.5, 64.6 2.28
PWK/PhJ f 17.714 2.0665   5 0.92416 0.1167 15.32, 20.85 -0.47
PWK/PhJ m 24.054 1.5167   5 0.67827 0.0631 22.03, 26.12 -0.39
WSB/EiJ f 11.853 0.60707   3 0.35049 0.0512 11.2, 12.4 -0.92
WSB/EiJ m 14.844 0.95325   5 0.42631 0.0642 13.28, 15.73 -1.16


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 22.182 1.2136617447 24.6105315417 19.7534684583
129S1/SvImJ m 26.502 1.2136617447 28.9305315417 24.0734684583
A/J f 24.0425 1.3569150814 26.7576808063 21.3273191937
A/J m 27.13 1.566830575 30.2652207389 23.9947792611
C57BL/6J f 21.616 1.2136617447 24.0445315417 19.1874684583
C57BL/6J m 30.274 1.2136617447 32.7025315417 27.8454684583
DBA/2J f 23.474 1.2136617447 25.9025315417 21.0454684583
DBA/2J m 32.67 1.2136617447 35.0985315417 30.2414684583
NOD/ShiLtJ f 24.5333333333 1.1079165246 26.7502691783 22.3163974884
NOD/ShiLtJ m 30.324 1.2136617447 32.7525315417 27.8954684583
NZO/HlLtJ f 56.525 1.3569150814 59.2401808063 53.8098191937
NZO/HlLtJ m 55.64 1.2136617447 58.0685315417 53.2114684583
PWK/PhJ f 17.714 1.2136617447 20.1425315417 15.2854684583
PWK/PhJ m 24.054 1.2136617447 26.4825315417 21.6254684583
WSB/EiJ f 11.8533333333 1.566830575 14.9885540722 8.7181125945
WSB/EiJ m 14.844 1.2136617447 17.2725315417 12.4154684583


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 24.342 0.8581884497 26.0592311214 22.6247688786
A/J both 25.58625 1.036361012 27.6600035951 23.5124964049
C57BL/6J both 25.945 0.8581884497 27.6622311214 24.2277688786
DBA/2J both 28.072 0.8581884497 29.7892311214 26.3547688786
NOD/ShiLtJ both 27.4286666667 0.8216528853 29.0727902926 25.7845430407
NZO/HlLtJ both 56.0825 0.9102463085 57.9038986563 54.2611013437
PWK/PhJ both 20.884 0.8581884497 22.6012311214 19.1667688786
WSB/EiJ both 13.3486666667 0.9909506649 15.3315543671 11.3657789662




  GWAS USING LINEAR MIXED MODELS