Project measure / variable:   Auwerx2   rer_basal_HFD

ID, description, units MPD:114638   rer_basal_HFD   basal respiratory exchange ratio (RER), prior to treadmill test (VCO2:VO2), 15 min time period, last 2 min analyzed   [ratio]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 19wks
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  STRAIN COMPARISON PLOT
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Auwerx2 - basal respiratory exchange ratio (RER), prior to treadmill test (VCO2:VO2), 15 min time period, last 2 min analyzed HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means0.78766   ratio 0.78159   ratio
Median of the strain means0.79125   ratio 0.78028   ratio
SD of the strain means± 0.02114 ± 0.02391
Coefficient of variation (CV)0.0268 0.0306
Min–max range of strain means0.74666   –   0.80968   ratio 0.75125   –   0.8187   ratio
Mean sample size per strain4.4   mice 3.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0 0.0 0.0012 0.9727
strain 7 0.0254 0.0036 2.9129 0.0123
sex:strain 7 0.0051 0.0007 0.5894 0.7614
Residuals 50 0.0624 0.0012


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.74666 0.02445   5 0.01093 0.0327 0.71481, 0.78253 -1.94
129S1/SvImJ m 0.75125 0.00448306   2   0.00317 0.006 0.74808, 0.75442 -1.27
A/J f 0.78263 0.01491   4 0.00745392 0.019 0.76597, 0.79925 -0.24
A/J m 0.79079 0.02214   5 0.00990297 0.028 0.76708, 0.82114 0.38
C57BL/6J f 0.79568 0.01552   3 0.00896078 0.0195 0.78275, 0.81289 0.38
C57BL/6J m 0.81613 0.01683   3 0.00971758 0.0206 0.79764, 0.83056 1.44
CAST/EiJ f 0.80894 0.08879   5 0.03971 0.1098 0.74603, 0.96319 1.01
CAST/EiJ m 0.78028 0.02722   2   0.01925 0.0349 0.76103, 0.79953 -0.05
DBA/2J f 0.80968 0.02443   5 0.01093 0.0302 0.79342, 0.85144 1.04
DBA/2J m 0.8187 0.02951   5 0.0132 0.036 0.77717, 0.853 1.55
NOD/ShiLtJ f 0.77261 0.02868   6 0.01171 0.0371 0.74375, 0.82497 -0.71
NOD/ShiLtJ m 0.78276 0.02648   5 0.01184 0.0338 0.74831, 0.80486 0.05
NZO/HlLtJ f 0.79125 0.02737   5 0.01224 0.0346 0.75656, 0.82014 0.17
NZO/HlLtJ m 0.75744 0.0   1   0.0 0.0 0.75744, 0.75744 -1.01
PWK/PhJ f 0.80819 0.04756   4 0.02378 0.0588 0.75781, 0.85569 0.97
PWK/PhJ m 0.77439 0.02321   5 0.01038 0.03 0.74283, 0.80417 -0.3
WSB/EiJ f 0.77331 0.02867   3 0.01655 0.0371 0.74953, 0.80514 -0.68
WSB/EiJ m 0.76258 0.01441   4 0.0072044 0.0189 0.74953, 0.78264 -0.79


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.746656 0.0157930849 0.7783773447 0.7149346553
129S1/SvImJ m 0.75125 0.0249710598 0.8014058498 0.7010941502
A/J f 0.7826325 0.0176572057 0.8180980415 0.7471669585
A/J m 0.79079 0.0157930849 0.8225113447 0.7590686553
C57BL/6J f 0.7956766667 0.020388785 0.8366287465 0.7547245868
C57BL/6J m 0.81613 0.020388785 0.8570820799 0.7751779201
CAST/EiJ f 0.808938 0.0157930849 0.8406593447 0.7772166553
CAST/EiJ m 0.78028 0.0249710598 0.8304358498 0.7301241502
DBA/2J f 0.809684 0.0157930849 0.8414053447 0.7779626553
DBA/2J m 0.818702 0.0157930849 0.8504233447 0.7869806553
NOD/ShiLtJ f 0.7726066667 0.0144170481 0.80156416 0.7436491733
NOD/ShiLtJ m 0.782756 0.0157930849 0.8144773447 0.7510346553
PWK/PhJ f 0.8081875 0.0176572057 0.8436530415 0.7727219585
PWK/PhJ m 0.774394 0.0157930849 0.8061153447 0.7426726553
WSB/EiJ f 0.7733066667 0.020388785 0.8142587465 0.7323545868
WSB/EiJ m 0.762585 0.0176572057 0.7980505415 0.7271194585


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.748953 0.0147730782 0.7786256009 0.7192803991
A/J both 0.78671125 0.0118448137 0.8105022585 0.7629202415
C57BL/6J both 0.8059033333 0.0144170481 0.8348608267 0.77694584
CAST/EiJ both 0.794609 0.0147730782 0.8242816009 0.7649363991
DBA/2J both 0.814193 0.0111673975 0.8366233779 0.7917626221
NOD/ShiLtJ both 0.7776813333 0.010691969 0.7991567852 0.7562058815
PWK/PhJ both 0.79129075 0.0118448137 0.8150817585 0.7674997415
WSB/EiJ both 0.7679458333 0.0134859136 0.7950330881 0.7408585786




  GWAS USING LINEAR MIXED MODELS