Project measure / variable:   Auwerx2   rer_basal_CD

ID, description, units MPD:114637   rer_basal_CD   basal respiratory exchange ratio (RER), prior to treadmill test (VCO2:VO2), 15 min time period, last 2 min analyzed   [ratio]  CD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 19wks
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  STRAIN COMPARISON PLOT
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Auwerx2 - basal respiratory exchange ratio (RER), prior to treadmill test (VCO2:VO2), 15 min time period, last 2 min analyzed CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means0.82356   ratio 0.83653   ratio
Median of the strain means0.81233   ratio 0.82556   ratio
SD of the strain means± 0.04621 ± 0.03206
Coefficient of variation (CV)0.0561 0.0383
Min–max range of strain means0.78225   –   0.93728   ratio 0.78658   –   0.88207   ratio
Mean sample size per strain4.2   mice 4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0086 0.0086 8.7069 0.0045
strain 7 0.033 0.0047 4.7538 0.0003
sex:strain 7 0.0065 0.0009 0.9295 0.4907
Residuals 59 0.0585 0.001


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.79351 0.02468   5 0.01104 0.0311 0.76772, 0.82733 -0.65
129S1/SvImJ m 0.81285 0.02174   5 0.00972325 0.0267 0.78683, 0.84572 -0.74
A/J f 0.82461 0.03083   4 0.01541 0.0374 0.79828, 0.86467 0.02
A/J m 0.81955 0.01104   3 0.00637674 0.0135 0.80742, 0.82903 -0.53
C57BL/6J f 0.79326 0.01941   5 0.00867935 0.0245 0.76372, 0.81542 -0.66
C57BL/6J m 0.82556 0.03485   5 0.01558 0.0422 0.78867, 0.87792 -0.34
CAST/EiJ f 0.93728 0.0   1   0.0 0.0 0.93728, 0.93728 2.46
CAST/EiJ m 0.88207 0.03013   3 0.0174 0.0342 0.84886, 0.90767 1.42
DBA/2J f 0.81233 0.01766   5 0.00789668 0.0217 0.78633, 0.83333 -0.24
DBA/2J m 0.85464 0.04473   5 0.02001 0.0523 0.77919, 0.89669 0.56
NOD/ShiLtJ f 0.82291 0.04381   6 0.01788 0.0532 0.77536, 0.89839 -0.01
NOD/ShiLtJ m 0.8772 0.02941   5 0.01315 0.0335 0.84725, 0.92011 1.27
NZO/HlLtJ f 0.83869 0.02611   4 0.01306 0.0311 0.80594, 0.861 0.33
NZO/HlLtJ m 0.85384 0.04343   5 0.01942 0.0509 0.78297, 0.89064 0.54
PWK/PhJ f 0.80722 0.01334   5 0.00596372 0.0165 0.78853, 0.82161 -0.35
PWK/PhJ m 0.81651 0.0274   5 0.01225 0.0336 0.79172, 0.84794 -0.62
WSB/EiJ f 0.78225 0.05193   3 0.02998 0.0664 0.73244, 0.83606 -0.89
WSB/EiJ m 0.78658 0.03052   5 0.01365 0.0388 0.753, 0.83561 -1.56


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.79351 0.0140838076 0.821691634 0.765328366
129S1/SvImJ m 0.812848 0.0140838076 0.841029634 0.784666366
A/J f 0.8246125 0.0157461756 0.8561205247 0.7931044753
A/J m 0.8195466667 0.0181821175 0.8559289997 0.7831643336
C57BL/6J f 0.79326 0.0140838076 0.821441634 0.765078366
C57BL/6J m 0.825556 0.0140838076 0.853737634 0.797374366
DBA/2J f 0.812326 0.0140838076 0.840507634 0.784144366
DBA/2J m 0.854642 0.0140838076 0.882823634 0.826460366
NOD/ShiLtJ f 0.8229133333 0.0128566986 0.8486395278 0.7971871389
NOD/ShiLtJ m 0.8772 0.0140838076 0.905381634 0.849018366
NZO/HlLtJ f 0.838695 0.0157461756 0.8702030247 0.8071869753
NZO/HlLtJ m 0.853842 0.0140838076 0.882023634 0.825660366
PWK/PhJ f 0.807218 0.0140838076 0.835399634 0.779036366
PWK/PhJ m 0.816514 0.0140838076 0.844695634 0.788332366
WSB/EiJ f 0.78225 0.0181821175 0.8186323331 0.7458676669
WSB/EiJ m 0.786584 0.0140838076 0.814765634 0.758402366


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.803179 0.0099587559 0.8231064245 0.7832515755
A/J both 0.8220795833 0.0120263403 0.8461442347 0.798014932
C57BL/6J both 0.809408 0.0099587559 0.8293354245 0.7894805755
DBA/2J both 0.833484 0.0099587559 0.8534114245 0.8135565755
NOD/ShiLtJ both 0.8500566667 0.0095347829 0.8691357231 0.8309776102
NZO/HlLtJ both 0.8462685 0.0105628557 0.8674047255 0.8251322745
PWK/PhJ both 0.811866 0.0099587559 0.8317934245 0.7919385755
WSB/EiJ both 0.784417 0.0114993808 0.8074272078 0.7614067922




  GWAS USING LINEAR MIXED MODELS