Project measure / variable:   Auwerx2   vert_act_night_HFD

ID, description, units MPD:114630   vert_act_night_HFD   vertical activity (beam breaks) at night, basal activity test, for 48h   [n/h]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 19wks
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  STRAIN COMPARISON PLOT
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Auwerx2 - vertical activity (beam breaks) at night, basal activity test, for 48h HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains8 strains
Mean of the strain means8708.0   n/h 10291.0   n/h
Median of the strain means6966.0   n/h 10862.0   n/h
SD of the strain means± 6082.0 ± 5593.0
Coefficient of variation (CV)0.6984 0.5434
Min–max range of strain means1570.0   –   16513.0   n/h 859.0   –   19154.0   n/h
Mean sample size per strain3.8   mice 4.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1979640.0179 1979640.0179 0.0283 0.8672
strain 6 657813922.1623 109635653.6937 1.5677 0.1805
sex:strain 6 983500184.2901 163916697.3817 2.3439 0.0483
Residuals 42 2937243842.0833 69934377.1925


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 6949.0 3432.0   5 1535.0 0.4938 3634.0, 10914.0 -0.29
129S1/SvImJ m 859.0 140.0   2   99.0 0.163 760.0, 958.0 -1.69
A/J f 6966.0 682.9   4 341.4 0.098 6016.0, 7624.0 -0.29
A/J m 5359.0 1532.0   5 685.0 0.2858 3412.0, 7293.0 -0.88
C57BL/6J f 3308.0 739.6   3 427.0 0.2235 2575.0, 4054.0 -0.89
C57BL/6J m 12243.0 3408.0   4 1704.0 0.2784 9660.0, 17142.0 0.35
CAST/EiJ f 16421.0 13747.0   5 6148.0 0.8372 5811.0, 40242.0 1.27
CAST/EiJ m 9630.0 1956.0   2   1383.0 0.2031 8247.0, 11013.0 -0.12
DBA/2J f 15320.0 7136.0   5 3191.0 0.4658 3326.0, 20869.0 1.09
DBA/2J m 12093.0 3735.0   5 1670.0 0.3088 7736.0, 16080.0 0.32
NOD/ShiLtJ f 9340.0 0.0   1   0.0 0.0 9340.0, 9340.0 0.1
NOD/ShiLtJ m 14386.0 11962.0   5 5350.0 0.8315 8217.0, 35756.0 0.73
NZO/HlLtJ f 1988.0 294.3   5 131.6 0.148 1649.0, 2417.0 -1.1
PWK/PhJ f 1570.0 901.3   3 520.4 0.5741 620.0, 2413.0 -1.17
PWK/PhJ m 19154.0 17743.0   5 7935.0 0.9263 7451.0, 50589.0 1.58
WSB/EiJ f 16513.0 15545.0   3 8975.0 0.9414 5762.0, 34337.0 1.28
WSB/EiJ m 8607.0 4474.0   5 2001.0 0.5197 5007.0, 15181.0 -0.3


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 6948.8 3739.9031322338 14496.2300814744 -598.6300814744
129S1/SvImJ m 859.0 5913.3060631283 12792.5347691646 -11074.5347691646
A/J f 6966.0 4181.3388164696 15404.2833588018 -1472.2833588018
A/J m 5359.2 3739.9031322338 12906.6300814744 -2188.2300814744
C57BL/6J f 3308.3333333333 4828.1941825235 13052.0236707384 -6435.3570040717
C57BL/6J m 12242.75 4181.3388164696 20681.0333588017 3804.4666411982
CAST/EiJ f 16420.8 3739.9031322338 23968.2300814744 8873.3699185256
CAST/EiJ m 9630.0 5913.3060631283 21563.5347691646 -2303.5347691646
DBA/2J f 15319.6 3739.9031322338 22867.0300814744 7772.1699185256
DBA/2J m 12092.8 3739.9031322338 19640.2300814744 4545.3699185256
PWK/PhJ f 1570.0 4828.1941825235 11313.6903374051 -8173.6903374051
PWK/PhJ m 19153.8 3739.9031322338 26701.2300814744 11606.3699185256
WSB/EiJ f 16513.3333333333 4828.1941825235 26257.0236707384 6769.6429959283
WSB/EiJ m 8607.2 3739.9031322338 16154.6300814744 1059.7699185256


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 3903.9 3498.3590451354 10963.8743788771 -3156.0743788771
A/J both 6162.6 2804.9273491753 11823.1725611058 502.0274388942
C57BL/6J both 7775.5416666667 3193.5502721215 14220.3870378659 1330.6962954674
CAST/EiJ both 13025.4 3498.3590451354 20085.3743788771 5965.4256211229
DBA/2J both 13706.2 2644.5108657833 19043.0389911419 8369.3610088581
PWK/PhJ both 10361.9 3053.6181204698 16524.3508563149 4199.4491436851
WSB/EiJ both 12560.2666666667 3053.6181204698 18722.7175229816 6397.8158103518




  GWAS USING LINEAR MIXED MODELS