Project measure / variable:   Auwerx2   temp_t2_CD

ID, description, units MPD:114611   temp_t2_CD   body temperature (rectal) in cold (4°C) room, 2h exposed to cold   [°C]  CD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 18wks
Procedure body temperature
Ontology mappings

  STRAIN COMPARISON PLOT
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Auwerx2 - body temperature (rectal) in cold (4°C) room, 2h exposed to cold CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means35.335   °C 34.909   °C
Median of the strain means35.375   °C 35.0   °C
SD of the strain means± 0.4996 ± 1.1896
Coefficient of variation (CV)0.0141 0.0341
Min–max range of strain means34.6   –   36.0   °C 33.14   –   36.72   °C
Mean sample size per strain4.3   mice 4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.587 0.587 1.4414 0.2345
strain 7 39.7619 5.6803 13.949 < 0.0001
sex:strain 7 16.7135 2.3876 5.8633 < 0.0001
Residuals 62 25.2475 0.4072


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 35.62 0.08367   5 0.03742 0.0023 35.5, 35.7 0.57
129S1/SvImJ m 35.42 0.40866   5 0.18276 0.0115 34.7, 35.7 0.43
A/J f 34.68 0.40866   5 0.18276 0.0118 34.1, 35.2 -1.31
A/J m 35.0 0.46904   5 0.20976 0.0134 34.2, 35.4 0.08
C57BL/6J f 34.6 0.84261   5 0.37683 0.0244 33.3, 35.4 -1.47
C57BL/6J m 33.64 0.63482   5 0.2839 0.0189 32.9, 34.4 -1.07
CAST/EiJ f 36.0 0.0   1   0.0 0.0 36.0, 36.0 1.33
CAST/EiJ m 33.8 0.17321   3 0.1 0.0051 33.7, 34.0 -0.93
DBA/2J f 34.92 0.79812   5 0.35693 0.0229 33.7, 35.8 -0.83
DBA/2J m 35.56 1.0597   5 0.47392 0.0298 34.6, 37.2 0.55
NOD/ShiLtJ f 35.367 0.62503   6 0.25517 0.0177 34.5, 36.1 0.06
NOD/ShiLtJ m 34.82 0.94974   5 0.42474 0.0273 33.8, 36.2 -0.07
NZO/HlLtJ f 35.375 0.5058   4 0.2529 0.0143 34.8, 35.8 0.08
NZO/HlLtJ m 33.14 0.251   5 0.11225 0.0076 32.9, 33.5 -1.49
PWK/PhJ f 35.62 0.26833   5 0.12 0.0075 35.4, 36.0 0.57
PWK/PhJ m 36.08 0.52154   5 0.23324 0.0145 35.2, 36.4 0.98
WSB/EiJ f 35.833 0.05774   3 0.03333 0.0016 35.8, 35.9 1.0
WSB/EiJ m 36.72 0.94181   5 0.42119 0.0256 35.2, 37.4 1.52


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 35.62 0.2853831607 36.1904728096 35.0495271904
129S1/SvImJ m 35.42 0.2853831607 35.9904728096 34.8495271904
A/J f 34.68 0.2853831607 35.2504728096 34.1095271904
A/J m 35.0 0.2853831607 35.5704728096 34.4295271904
C57BL/6J f 34.6 0.2853831607 35.1704728096 34.0295271904
C57BL/6J m 33.64 0.2853831607 34.2104728096 33.0695271904
DBA/2J f 34.92 0.2853831607 35.4904728096 34.3495271904
DBA/2J m 35.56 0.2853831607 36.1304728096 34.9895271904
NOD/ShiLtJ f 35.3666666667 0.260517991 35.8874347104 34.8458986229
NOD/ShiLtJ m 34.82 0.2853831607 35.3904728096 34.2495271904
NZO/HlLtJ f 35.375 0.3190680734 36.0128079908 34.7371920092
NZO/HlLtJ m 33.14 0.2853831607 33.7104728096 32.5695271904
PWK/PhJ f 35.62 0.2853831607 36.1904728096 35.0495271904
PWK/PhJ m 36.08 0.2853831607 36.6504728096 35.5095271904
WSB/EiJ f 35.8333333333 0.3684280762 36.5698105637 35.096856103
WSB/EiJ m 36.72 0.2853831607 37.2904728096 36.1495271904


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 35.52 0.2017963681 35.9233851921 35.1166148079
A/J both 34.84 0.2017963681 35.2433851921 34.4366148079
C57BL/6J both 34.12 0.2017963681 34.5233851921 33.7166148079
DBA/2J both 35.24 0.2017963681 35.6433851921 34.8366148079
NOD/ShiLtJ both 35.0933333333 0.1932053131 35.4795452512 34.7071214155
NZO/HlLtJ both 34.2575 0.2140373705 34.6853546072 33.8296453928
PWK/PhJ both 35.85 0.2017963681 36.2533851921 35.4466148079
WSB/EiJ both 36.2766666667 0.2330143749 36.7424557652 35.8108775681




  GWAS USING LINEAR MIXED MODELS