Project measure / variable:   Auwerx2   bw_16wks_ogtt_HFD

ID, description, units MPD:114582   bw_16wks_ogtt_HFD   body weight loss following 16h fast, prior to oral glucose tolerance test (OGTT), 16 wks of age   [g]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 16wks
Procedure body weight
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  STRAIN COMPARISON PLOT
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Auwerx2 - body weight loss following 16h fast, prior to oral glucose tolerance test (OGTT), 16 wks of age HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means1.554   g 1.8709   g
Median of the strain means1.34   g 1.765   g
SD of the strain means± 0.47154 ± 0.51345
Coefficient of variation (CV)0.3034 0.2744
Min–max range of strain means1.06   –   2.168   g 1.245   –   2.65   g
Mean sample size per strain4.3   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.8419 1.8419 7.9182 0.0069
strain 7 10.93 1.5614 6.7124 < 0.0001
sex:strain 7 0.9104 0.1301 0.5591 0.7853
Residuals 51 11.8636 0.2326


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1.136 0.24866   5 0.1112 0.2189 0.85, 1.34 -0.89
129S1/SvImJ m 1.765 0.06364   2   0.045 0.0361 1.72, 1.81 -0.21
A/J f 1.2375 0.19103   4 0.09551 0.1544 1.1, 1.51 -0.67
A/J m 1.332 0.08701   5 0.03891 0.0653 1.24, 1.47 -1.05
C57BL/6J f 1.7867 0.09713   3 0.05608 0.0544 1.68, 1.87 0.49
C57BL/6J m 2.3125 1.0362   4 0.51808 0.4481 1.53, 3.81 0.86
CAST/EiJ f 1.09 0.11446   5 0.05119 0.105 1.02, 1.29 -0.98
CAST/EiJ m 1.245 0.17678   2   0.125 0.142 1.12, 1.37 -1.22
DBA/2J f 2.14 0.66951   5 0.29942 0.3129 1.28, 3.12 1.24
DBA/2J m 2.514 0.62448   5 0.27928 0.2484 1.9, 3.28 1.25
NOD/ShiLtJ f 1.34 0.66727   5 0.29841 0.498 0.7, 2.46 -0.45
NOD/ShiLtJ m 1.518 0.33996   5 0.15203 0.2239 0.94, 1.77 -0.69
NZO/HlLtJ f 2.168 0.34608   5 0.15477 0.1596 1.83, 2.64 1.3
NZO/HlLtJ m 2.65 0.0   1   0.0 0.0 2.65, 2.65 1.52
PWK/PhJ f 2.0275 0.23215   4 0.11607 0.1145 1.69, 2.22 1.0
PWK/PhJ m 1.904 0.43483   5 0.19446 0.2284 1.27, 2.38 0.06
WSB/EiJ f 1.06 0.87504   3 0.50521 0.8255 0.05, 1.59 -1.05
WSB/EiJ m 1.598 0.16084   5 0.07193 0.1007 1.39, 1.76 -0.53


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1.136 0.2156939705 1.5690237144 0.7029762856
129S1/SvImJ m 1.765 0.3410421121 2.4496706092 1.0803293908
A/J f 1.2375 0.2411531901 1.7216352307 0.7533647693
A/J m 1.332 0.2156939705 1.7650237144 0.8989762856
C57BL/6J f 1.7866666667 0.2784597185 2.3456978782 1.2276354552
C57BL/6J m 2.3125 0.2411531901 2.7966352307 1.8283647693
CAST/EiJ f 1.09 0.2156939705 1.5230237144 0.6569762856
CAST/EiJ m 1.245 0.3410421121 1.9296706092 0.5603293908
DBA/2J f 2.14 0.2156939705 2.5730237144 1.7069762856
DBA/2J m 2.514 0.2156939705 2.9470237144 2.0809762856
NOD/ShiLtJ f 1.34 0.2156939705 1.7730237144 0.9069762856
NOD/ShiLtJ m 1.518 0.2156939705 1.9510237144 1.0849762856
PWK/PhJ f 2.0275 0.2411531901 2.5116352307 1.5433647693
PWK/PhJ m 1.904 0.2156939705 2.3370237144 1.4709762856
WSB/EiJ f 1.06 0.2784597185 1.6190312115 0.5009687885
WSB/EiJ m 1.598 0.2156939705 2.0310237144 1.1649762856


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1.4505 0.2017632345 1.8555565949 1.0454434051
A/J both 1.28475 0.1617704778 1.6095177858 0.9599822142
C57BL/6J both 2.0495833333 0.1841837913 2.4193477235 1.6798189431
CAST/EiJ both 1.1675 0.2017632345 1.5725565949 0.7624434051
DBA/2J both 2.327 0.1525186692 2.6331940049 2.0208059951
NOD/ShiLtJ both 1.429 0.1525186692 1.7351940049 1.1228059951
PWK/PhJ both 1.96575 0.1617704778 2.2905177858 1.6409822142
WSB/EiJ both 1.329 0.1761133894 1.6825623823 0.9754376177




  GWAS USING LINEAR MIXED MODELS