Project measure / variable:   Auwerx2   bw_16wks_ogtt_CD

ID, description, units MPD:114581   bw_16wks_ogtt_CD   body weight loss following 16h fast, prior to oral glucose tolerance test (OGTT), 16 wks of age   [g]  CD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 16wks
Procedure body weight
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  STRAIN COMPARISON PLOT
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Auwerx2 - body weight loss following 16h fast, prior to oral glucose tolerance test (OGTT), 16 wks of age CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means1.8442   g 2.5375   g
Median of the strain means1.58   g 2.436   g
SD of the strain means± 0.54503 ± 0.74621
Coefficient of variation (CV)0.2955 0.2941
Min–max range of strain means1.25   –   2.758   g 1.748   –   3.694   g
Mean sample size per strain4.1   mice 4.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 7.8941 7.8941 23.7335 < 0.0001
strain 7 27.0946 3.8707 11.637 < 0.0001
sex:strain 7 2.215 0.3164 0.9513 0.4748
Residuals 59 19.6243 0.3326


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1.504 0.35423   5 0.15842 0.2355 1.23, 2.11 -0.62
129S1/SvImJ m 1.748 0.446   5 0.19946 0.2552 1.1, 2.18 -1.06
A/J f 1.58 0.34699   5 0.15518 0.2196 1.0, 1.89 -0.48
A/J m 1.886 0.10877   5 0.04864 0.0577 1.75, 2.02 -0.87
C57BL/6J f 2.108 0.34996   5 0.15651 0.166 1.68, 2.56 0.48
C57BL/6J m 2.436 0.31358   5 0.14024 0.1287 2.06, 2.79 -0.14
CAST/EiJ f 1.33 0.0   1   0.0 0.0 1.33, 1.33 -0.94
CAST/EiJ m 1.9867 0.31182   3 0.18003 0.157 1.75, 2.34 -0.74
DBA/2J f 2.758 0.23721   5 0.10608 0.086 2.53, 3.09 1.68
DBA/2J m 3.694 0.46404   5 0.20752 0.1256 3.25, 4.45 1.55
NOD/ShiLtJ f 1.4125 0.22926   4 0.11463 0.1623 1.1, 1.65 -0.79
NOD/ShiLtJ m 2.472 0.32492   5 0.14531 0.1314 1.92, 2.74 -0.09
NZO/HlLtJ f 2.415 0.30903   4 0.15452 0.128 2.12, 2.85 1.05
NZO/HlLtJ m 3.586 0.68167   5 0.30485 0.1901 2.79, 4.4 1.41
PWK/PhJ f 2.24 0.5235   5 0.23412 0.2337 1.85, 3.16 0.73
PWK/PhJ m 3.085 1.2185   4 0.60923 0.395 2.18, 4.86 0.73
WSB/EiJ f 1.25 0.32   3 0.18475 0.256 0.93, 1.57 -1.09
WSB/EiJ m 1.944 1.3554   5 0.60614 0.6972 0.03, 3.7 -0.8


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1.504 0.2579207275 2.0200981837 0.9879018163
129S1/SvImJ m 1.748 0.2579207275 2.2640981837 1.2319018163
A/J f 1.58 0.2579207275 2.0960981837 1.0639018163
A/J m 1.886 0.2579207275 2.4020981837 1.3699018163
C57BL/6J f 2.108 0.2579207275 2.6240981837 1.5919018163
C57BL/6J m 2.436 0.2579207275 2.9520981837 1.9199018163
DBA/2J f 2.758 0.2579207275 3.2740981837 2.2419018163
DBA/2J m 3.694 0.2579207275 4.2100981837 3.1779018163
NOD/ShiLtJ f 1.4125 0.2883641398 1.9895153109 0.8354846891
NOD/ShiLtJ m 2.472 0.2579207275 2.9880981837 1.9559018163
NZO/HlLtJ f 2.415 0.2883641398 2.9920153109 1.8379846891
NZO/HlLtJ m 3.586 0.2579207275 4.1020981837 3.0699018163
PWK/PhJ f 2.24 0.2579207275 2.7560981837 1.7239018163
PWK/PhJ m 3.085 0.2883641398 3.6620153109 2.5079846891
WSB/EiJ f 1.25 0.3329742275 1.9162798902 0.5837201098
WSB/EiJ m 1.944 0.2579207275 2.4600981837 1.4279018163


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1.626 0.1823774955 1.9909365255 1.2610634745
A/J both 1.733 0.1823774955 2.0979365255 1.3680634745
C57BL/6J both 2.272 0.1823774955 2.6369365255 1.9070634745
DBA/2J both 3.226 0.1823774955 3.5909365255 2.8610634745
NOD/ShiLtJ both 1.94225 0.1934405457 2.3293236378 1.5551763622
NZO/HlLtJ both 3.0005 0.1934405457 3.3875736378 2.6134263622
PWK/PhJ both 2.6625 0.1934405457 3.0495736378 2.2754263622
WSB/EiJ both 1.597 0.2105913922 2.0183924024 1.1756075976




  GWAS USING LINEAR MIXED MODELS