Project measure / variable:   Auwerx2   rer_night_HFD

ID, description, units MPD:114580   rer_night_HFD   respiratory exchange rate (VCO2:VO2), 24h test, night time average   [ratio]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 14wks
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  STRAIN COMPARISON PLOT
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Auwerx2 - respiratory exchange rate (VCO2:VO2), 24h test, night time average HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means0.77336   ratio 0.75315   ratio
Median of the strain means0.77205   ratio 0.76143   ratio
SD of the strain means± 0.01347 ± 0.02173
Coefficient of variation (CV)0.0174 0.0289
Min–max range of strain means0.75771   –   0.80571   ratio 0.708   –   0.77465   ratio
Mean sample size per strain4.4   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.004 0.004 14.2121 0.0004
strain 7 0.0035 0.0005 1.7861 0.11
sex:strain 7 0.0084 0.0012 4.3047 0.0008
Residuals 52 0.0146 0.0003


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.77205 0.00785213   5 0.00351158 0.0102 0.75876, 0.77757 -0.1
129S1/SvImJ m 0.77449 0.00292742   2   0.00207 0.0038 0.77242, 0.77656 0.98
A/J f 0.80571 0.01003   4 0.00501535 0.0124 0.79495, 0.81639 2.4
A/J m 0.74967 0.01287   5 0.00575691 0.0172 0.73, 0.76482 -0.16
C57BL/6J f 0.77406 0.01109   3 0.00640555 0.0143 0.762, 0.78383 0.05
C57BL/6J m 0.74038 0.01377   4 0.00688445 0.0186 0.72265, 0.75545 -0.59
CAST/EiJ f 0.7639 0.01184   5 0.0052971 0.0155 0.74767, 0.77507 -0.7
CAST/EiJ m 0.76143 0.03272   2   0.02314 0.043 0.73829, 0.78457 0.38
DBA/2J f 0.76631 0.02398   5 0.01073 0.0313 0.73827, 0.79714 -0.52
DBA/2J m 0.77001 0.00829597   5 0.00371007 0.0108 0.76041, 0.77887 0.78
NOD/ShiLtJ f 0.77411 0.03403   6 0.01389 0.044 0.73524, 0.82289 0.06
NOD/ShiLtJ m 0.76152 0.01372   5 0.00613501 0.018 0.74112, 0.77712 0.39
NZO/HlLtJ f 0.77618 0.01517   5 0.00678578 0.0195 0.7533, 0.78976 0.21
NZO/HlLtJ m 0.708 0.0   1   0.0 0.0 0.708, 0.708 -2.08
PWK/PhJ f 0.77019 0.00345775   4 0.00172887 0.0045 0.76684, 0.77407 -0.24
PWK/PhJ m 0.73821 0.01694   5 0.00757364 0.0229 0.72171, 0.76324 -0.69
WSB/EiJ f 0.75771 0.01573   3 0.00908309 0.0208 0.74447, 0.7751 -1.16
WSB/EiJ m 0.77465 0.0051822   5 0.00231755 0.0067 0.76844, 0.78283 0.99


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.772052 0.0074860672 0.7870738928 0.7570301072
129S1/SvImJ m 0.77449 0.0118365115 0.798241698 0.750738302
A/J f 0.805715 0.0083696776 0.8225099868 0.7889200132
A/J m 0.749668 0.0074860672 0.7646898928 0.7346461072
C57BL/6J f 0.7740633333 0.0096644712 0.7934565136 0.7546701531
C57BL/6J m 0.740375 0.0083696776 0.7571699868 0.7235800132
CAST/EiJ f 0.763904 0.0074860672 0.7789258928 0.7488821072
CAST/EiJ m 0.76143 0.0118365115 0.785181698 0.737678302
DBA/2J f 0.766312 0.0074860672 0.7813338928 0.7512901072
DBA/2J m 0.770012 0.0074860672 0.7850338928 0.7549901072
NOD/ShiLtJ f 0.774105 0.0068338131 0.7878180493 0.7603919507
NOD/ShiLtJ m 0.761518 0.0074860672 0.7765398928 0.7464961072
PWK/PhJ f 0.770195 0.0083696776 0.7869899868 0.7534000132
PWK/PhJ m 0.738214 0.0074860672 0.7532358928 0.7231921072
WSB/EiJ f 0.7577066667 0.0096644712 0.7770998469 0.7383134864
WSB/EiJ m 0.774646 0.0074860672 0.7896678928 0.7596241072


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.773271 0.0070025747 0.7873226941 0.7592193059
A/J both 0.7776915 0.0056145504 0.7889579196 0.7664250804
C57BL/6J both 0.7572191667 0.0063924468 0.7700465497 0.7443917837
CAST/EiJ both 0.762667 0.0070025747 0.7767186941 0.7486153059
DBA/2J both 0.768162 0.0052934489 0.7787840823 0.7575399177
NOD/ShiLtJ both 0.7678115 0.0050680915 0.7779813695 0.7576416305
PWK/PhJ both 0.7542045 0.0056145504 0.7654709196 0.7429380804
WSB/EiJ both 0.7661763333 0.0061123483 0.7784416575 0.7539110092




  GWAS USING LINEAR MIXED MODELS