Project measure / variable:   Auwerx2   ltm_pct_HFD

ID, description, units MPD:114568   ltm_pct_HFD   percentage lean tissue mass   [%]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 14wks
Procedure MRI
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  STRAIN COMPARISON PLOT
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Auwerx2 - percentage lean tissue mass HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means72.77   % 69.27   %
Median of the strain means76.77   % 68.5   %
SD of the strain means± 12.438 ± 12.516
Coefficient of variation (CV)0.1709 0.1807
Min–max range of strain means45.928   –   85.33   % 48.334   –   87.41   %
Mean sample size per strain4.9   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 307.1644 307.1644 10.4288 0.0021
strain 7 4307.4845 615.3549 20.8924 < 0.0001
sex:strain 7 605.7856 86.5408 2.9382 0.0108
Residuals 56 1649.3961 29.4535


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 76.04 2.5048   5 1.1202 0.0329 73.95, 79.76 0.26
129S1/SvImJ m 62.42 4.6457   2   3.285 0.0744 59.14, 65.71 -0.55
A/J f 77.45 5.5782   4 2.7891 0.072 69.67, 82.82 0.38
A/J m 70.09 2.8378   5 1.2691 0.0405 66.64, 72.61 0.07
C57BL/6J f 80.33 3.582   3 2.0681 0.0446 76.2, 82.59 0.61
C57BL/6J m 68.5 6.2287   4 3.1143 0.0909 61.3, 76.04 -0.06
CAST/EiJ f 85.33 1.3163   5 0.58865 0.0154 83.34, 86.46 1.01
CAST/EiJ m 84.82 3.4083   2   2.41 0.0402 82.41, 87.23 1.24
DBA/2J f 62.78 4.0467   5 1.8097 0.0645 57.84, 68.84 -0.8
DBA/2J m 65.18 1.1136   5 0.49802 0.0171 63.26, 65.99 -0.33
NOD/ShiLtJ f 76.77 10.972   10 3.4698 0.1429 58.4, 90.22 0.32
NOD/ShiLtJ m 77.74 1.8898   5 0.84516 0.0243 75.26, 79.53 0.68
NZO/HlLtJ f 45.928 1.5272   5 0.68298 0.0333 43.464, 47.665 -2.16
NZO/HlLtJ m 48.334 0.0   1   0.0 0.0 48.334, 48.334 -1.67
PWK/PhJ f 66.72 3.1709   4 1.5855 0.0475 62.19, 69.43 -0.49
PWK/PhJ m 58.91 2.5672   5 1.1481 0.0436 54.61, 61.01 -0.83
WSB/EiJ f 83.6 6.4227   3 3.7082 0.0768 77.37, 90.2 0.87
WSB/EiJ m 87.41 1.5212   5 0.68029 0.0174 84.96, 89.09 1.45


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 76.036 2.4270765385 80.8980185497 71.1739814503
129S1/SvImJ m 62.425 3.8375449586 70.1125263215 54.7374736785
A/J f 77.45 2.7135540634 82.8859019925 72.0140980075
A/J m 70.092 2.4270765385 74.9540185497 65.2299814503
C57BL/6J f 80.33 3.1333423379 86.6068389573 74.0531610427
C57BL/6J m 68.5025 2.7135540634 73.9384019925 63.0665980075
CAST/EiJ f 85.33 2.4270765385 90.1920185497 80.4679814503
CAST/EiJ m 84.82 3.8375449586 92.5075263215 77.1324736785
DBA/2J f 62.778 2.4270765385 67.6400185497 57.9159814503
DBA/2J m 65.18 2.4270765385 70.0420185497 60.3179814503
NOD/ShiLtJ f 76.768 1.7162022788 80.2059662868 73.3300337132
NOD/ShiLtJ m 77.742 2.4270765385 82.6040185497 72.8799814503
PWK/PhJ f 66.7175 2.7135540634 72.1534019925 61.2815980075
PWK/PhJ m 58.912 2.4270765385 63.7740185497 54.0499814503
WSB/EiJ f 83.6033333333 3.1333423379 89.8801722907 77.326494376
WSB/EiJ m 87.408 2.4270765385 92.2700185497 82.5459814503


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 69.2305 2.2703222147 73.7785019053 64.6824980947
A/J both 73.771 1.8203074039 77.4175139123 70.1244860877
C57BL/6J both 74.41625 2.0725111496 78.5679887252 70.2645112748
CAST/EiJ both 85.075 2.2703222147 89.6230019053 80.5269980947
DBA/2J both 63.979 1.7162022788 67.4169662868 60.5410337132
NOD/ShiLtJ both 77.255 1.4862747715 80.2323661417 74.2776338583
PWK/PhJ both 62.81475 1.8203074039 66.4612639123 59.1682360877
WSB/EiJ both 85.5056666667 1.9816996953 89.4754881889 81.5358451444




  GWAS USING LINEAR MIXED MODELS