Project measure / variable:   Auwerx2   ltm_HFD

ID, description, units MPD:114564   ltm_HFD   lean tissue mass   [g]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 14wks
Procedure MRI
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  STRAIN COMPARISON PLOT
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Auwerx2 - lean tissue mass HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means18.368   g 22.17   g
Median of the strain means17.538   g 20.334   g
SD of the strain means± 5.9814 ± 6.6546
Coefficient of variation (CV)0.3256 0.3002
Min–max range of strain means11.064   –   31.219   g 14.009   –   34.559   g
Mean sample size per strain4.9   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 220.9428 220.9428 282.398 < 0.0001
strain 7 1208.3246 172.6178 220.6314 < 0.0001
sex:strain 7 58.6384 8.3769 10.7069 < 0.0001
Residuals 56 43.8133 0.7824


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 17.538 0.52348   5 0.23411 0.0298 16.839, 18.186 -0.14
129S1/SvImJ m 20.334 0.647   2   0.4575 0.0318 19.876, 20.791 -0.28
A/J f 17.482 0.39189   4 0.19595 0.0224 16.948, 17.878 -0.15
A/J m 19.992 0.65759   5 0.29408 0.0329 19.001, 20.512 -0.33
C57BL/6J f 18.82 0.25182   3 0.14539 0.0134 18.529, 18.972 0.08
C57BL/6J m 26.293 0.81031   4 0.40515 0.0308 25.291, 27.215 0.62
CAST/EiJ f 11.386 0.67543   5 0.30206 0.0593 10.742, 12.342 -1.17
CAST/EiJ m 14.894 0.27577   2   0.195 0.0185 14.699, 15.089 -1.09
DBA/2J f 20.754 0.52855   5 0.23638 0.0255 20.243, 21.427 0.4
DBA/2J m 26.395 1.628   5 0.72806 0.0617 24.518, 28.567 0.63
NOD/ShiLtJ f 20.927 0.9687   10 0.30633 0.0463 19.82, 22.822 0.43
NOD/ShiLtJ m 25.852 0.97719   5 0.43701 0.0378 24.87, 27.055 0.55
NZO/HlLtJ f 31.219 1.0257   5 0.45871 0.0329 30.258, 32.889 2.15
NZO/HlLtJ m 34.559 0.0   1   0.0 0.0 34.559, 34.559 1.86
PWK/PhJ f 16.121 1.0085   4 0.50425 0.0626 14.614, 16.705 -0.38
PWK/PhJ m 17.198 0.98723   5 0.4415 0.0574 15.636, 18.159 -0.75
WSB/EiJ f 11.064 0.79869   3 0.46112 0.0722 10.364, 11.934 -1.22
WSB/EiJ m 14.009 0.98759   5 0.44166 0.0705 12.753, 15.038 -1.23


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 17.5384 0.3955706755 18.3308232844 16.7459767156
129S1/SvImJ m 20.3335 0.6254521551 21.5864312249 19.0805687751
A/J f 17.482 0.4422614602 18.3679561655 16.5960438345
A/J m 19.992 0.3955706755 20.7844232844 19.1995767156
C57BL/6J f 18.8196666667 0.5106795462 19.8426807279 17.7966526054
C57BL/6J m 26.2935 0.4422614602 27.1794561655 25.4075438345
CAST/EiJ f 11.3856 0.3955706755 12.1780232844 10.5931767156
CAST/EiJ m 14.894 0.6254521551 16.1469312249 13.6410687751
DBA/2J f 20.754 0.3955706755 21.5464232844 19.9615767156
DBA/2J m 26.3954 0.3955706755 27.1878232844 25.6029767156
NOD/ShiLtJ f 20.9269 0.2797107071 21.487227878 20.366572122
NOD/ShiLtJ m 25.8524 0.3955706755 26.6448232844 25.0599767156
PWK/PhJ f 16.12125 0.4422614602 17.0072061655 15.2352938345
PWK/PhJ m 17.1982 0.3955706755 17.9906232844 16.4057767156
WSB/EiJ f 11.064 0.5106795462 12.0870140612 10.0409859388
WSB/EiJ m 14.0086 0.3955706755 14.8010232844 13.2161767156


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 18.93595 0.370022485 19.6771941089 18.1947058911
A/J both 18.737 0.2966780067 19.3313174633 18.1426825367
C57BL/6J both 22.5565833333 0.3377827697 23.2332435318 21.8799231349
CAST/EiJ both 13.1398 0.370022485 13.8810441089 12.3985558911
DBA/2J both 23.5747 0.2797107071 24.135027878 23.014372122
NOD/ShiLtJ both 23.38965 0.2422365781 23.8749081768 22.9043918232
PWK/PhJ both 16.659725 0.2966780067 17.2540424633 16.0654075367
WSB/EiJ both 12.5363 0.3229821041 13.1833109024 11.8892890976




  GWAS USING LINEAR MIXED MODELS