Project measure / variable:   Auwerx2   ltm_CD

ID, description, units MPD:114563   ltm_CD   lean tissue mass   [g]  CD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 14wks
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  STRAIN COMPARISON PLOT
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Auwerx2 - lean tissue mass CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means18.007   g 22.059   g
Median of the strain means18.373   g 21.5   g
SD of the strain means± 5.6529 ± 6.4893
Coefficient of variation (CV)0.3139 0.2942
Min–max range of strain means9.962   –   29.59   g 12.692   –   33.278   g
Mean sample size per strain4.0   mice 4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 326.675 326.675 133.0069 < 0.0001
strain 7 2090.8971 298.6996 121.6166 < 0.0001
sex:strain 7 54.3297 7.7614 3.1601 0.0066
Residuals 59 144.9085 2.4561


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 18.023 0.45965   5 0.20556 0.0255 17.591, 18.714 0.0
129S1/SvImJ m 21.5 1.3827   5 0.61837 0.0643 20.534, 23.831 -0.09
A/J f 18.746 1.5277   5 0.68321 0.0815 17.843, 21.455 0.13
A/J m 21.148 1.0569   5 0.47264 0.05 19.556, 22.32 -0.14
C57BL/6J f 18.373 1.2669   5 0.56658 0.069 17.006, 19.654 0.06
C57BL/6J m 25.822 1.6311   5 0.72944 0.0632 23.443, 27.431 0.58
CAST/EiJ f 12.135 0.0   1   0.0 0.0 12.135, 12.135 -1.04
CAST/EiJ m 14.195 0.45517   3 0.26279 0.0321 13.918, 14.72 -1.21
DBA/2J f 20.534 1.0997   5 0.4918 0.0536 19.345, 22.301 0.45
DBA/2J m 24.916 1.1559   5 0.51692 0.0464 23.805, 26.73 0.44
NOD/ShiLtJ f 20.029 0.38143   3 0.22022 0.019 19.782, 20.468 0.36
NOD/ShiLtJ m 26.827 0.67775   5 0.3031 0.0253 25.711, 27.392 0.73
NZO/HlLtJ f 29.59 1.576   4 0.78799 0.0533 28.243, 31.87 2.05
NZO/HlLtJ m 33.278 4.4688   5 1.9985 0.1343 29.462, 38.306 1.73
PWK/PhJ f 14.672 0.64985   5 0.29062 0.0443 13.748, 15.42 -0.59
PWK/PhJ m 18.155 0.64825   5 0.28991 0.0357 17.422, 18.902 -0.6
WSB/EiJ f 9.962 0.58889   3 0.33999 0.0591 9.578, 10.64 -1.42
WSB/EiJ m 12.692 0.67928   5 0.30378 0.0535 11.711, 13.393 -1.44


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 18.0226 0.7008674245 19.425032477 16.620167523
129S1/SvImJ m 21.4998 0.7008674245 22.902232477 20.097367523
A/J f 18.7458 0.7008674245 20.148232477 17.343367523
A/J m 21.1482 0.7008674245 22.550632477 19.745767523
C57BL/6J f 18.3726 0.7008674245 19.775032477 16.970167523
C57BL/6J m 25.8222 0.7008674245 27.224632477 24.419767523
DBA/2J f 20.5338 0.7008674245 21.936232477 19.131367523
DBA/2J m 24.9156 0.7008674245 26.318032477 23.513167523
NOD/ShiLtJ f 20.0286666667 0.9048159543 21.8391992092 18.2181341241
NOD/ShiLtJ m 26.8274 0.7008674245 28.229832477 25.424967523
NZO/HlLtJ f 29.59 0.7835936022 31.1579671762 28.0220328238
NZO/HlLtJ m 33.2784 0.7008674245 34.680832477 31.875967523
PWK/PhJ f 14.6716 0.7008674245 16.074032477 13.269167523
PWK/PhJ m 18.1546 0.7008674245 19.557032477 16.752167523
WSB/EiJ f 9.962 0.9048159543 11.7725325425 8.1514674575
WSB/EiJ m 12.6924 0.7008674245 14.094832477 11.289967523


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 19.7612 0.4955881085 20.7528695146 18.7695304854
A/J both 19.947 0.4955881085 20.9386695146 18.9553304854
C57BL/6J both 22.0974 0.4955881085 23.0890695146 21.1057304854
DBA/2J both 22.7247 0.4955881085 23.7163695146 21.7330304854
NOD/ShiLtJ both 23.4280333333 0.5722558558 24.5731146558 22.2829520109
NZO/HlLtJ both 31.4342 0.5256505683 32.4860243577 30.3823756423
PWK/PhJ both 16.4131 0.4955881085 17.4047695146 15.4214304854
WSB/EiJ both 11.3272 0.5722558558 12.4722813224 10.1821186776




  GWAS USING LINEAR MIXED MODELS