Project measure / variable:   Auwerx2   fat_HFD

ID, description, units MPD:114562   fat_HFD   fat tissue mass   [g]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 14wks
Procedure MRI
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  STRAIN COMPARISON PLOT
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Auwerx2 - fat tissue mass HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means9.1537   g 12.146   g
Median of the strain means5.1698   g 11.93   g
SD of the strain means± 11.034 ± 10.715
Coefficient of variation (CV)1.2054 0.8822
Min–max range of strain means1.7154   –   37.342   g 1.9364   –   38.296   g
Mean sample size per strain4.9   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 170.3773 170.3773 34.8346 < 0.0001
strain 7 839.8037 119.972 24.5289 < 0.0001
sex:strain 7 111.6 15.9429 3.2596 0.0057
Residuals 56 273.898 4.891


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 5.0178 0.76999   5 0.34435 0.1535 3.871, 5.681 -0.37
129S1/SvImJ m 11.954 1.9262   2   1.362 0.1611 10.592, 13.316 -0.02
A/J f 5.1698 1.8003   4 0.90013 0.3482 3.585, 7.759 -0.36
A/J m 8.2238 0.93469   5 0.41801 0.1137 7.25, 9.781 -0.37
C57BL/6J f 4.47 0.9172   3 0.52955 0.2052 3.838, 5.522 -0.42
C57BL/6J m 12.707 3.3603   4 1.6801 0.2644 8.974, 16.671 0.05
CAST/EiJ f 1.7154 0.24273   5 0.10855 0.1415 1.428, 2.021 -0.67
CAST/EiJ m 2.6465 0.67246   2   0.4755 0.2541 2.171, 3.122 -0.89
DBA/2J f 12.181 2.2637   5 1.0123 0.1858 8.896, 14.937 0.27
DBA/2J m 14.043 0.98447   5 0.44027 0.0701 12.918, 15.531 0.18
NOD/ShiLtJ f 6.6318 4.2925   10 1.3574 0.6473 1.866, 15.314 -0.23
NOD/ShiLtJ m 7.578 0.98797   5 0.44183 0.1304 6.586, 9.142 -0.43
NZO/HlLtJ f 37.342 2.0891   5 0.93426 0.0559 35.721, 40.838 2.55
NZO/HlLtJ m 38.296 0.0   1   0.0 0.0 38.296, 38.296 2.44
PWK/PhJ f 7.9202 1.584   4 0.79199 0.2 6.144, 9.963 -0.11
PWK/PhJ m 11.93 1.9159   5 0.85683 0.1606 9.789, 15.05 -0.02
WSB/EiJ f 1.9353 0.90862   3 0.52459 0.4695 1.151, 2.931 -0.65
WSB/EiJ m 1.9364 0.31171   5 0.1394 0.161 1.534, 2.32 -0.95


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 5.0178 0.9890435586 6.9990923293 3.0365076707
129S1/SvImJ m 11.954 1.5638151751 15.0866982356 8.8213017644
A/J f 5.16975 1.1057843148 7.3849021658 2.9545978342
A/J m 8.2238 0.9890435586 10.2050923293 6.2425076707
C57BL/6J f 4.47 1.2768497437 7.0278373984 1.9121626016
C57BL/6J m 12.70725 1.1057843148 14.9224021658 10.4920978342
CAST/EiJ f 1.7154 0.9890435586 3.6966923293 -0.2658923293
CAST/EiJ m 2.6465 1.5638151751 5.7791982356 -0.4861982356
DBA/2J f 12.181 0.9890435586 14.1622923293 10.1997076707
DBA/2J m 14.0428 0.9890435586 16.0240923293 12.0615076707
NOD/ShiLtJ f 6.6318 0.6993594072 8.0327852415 5.2308147585
NOD/ShiLtJ m 7.578 0.9890435586 9.5592923293 5.5967076707
PWK/PhJ f 7.92025 1.1057843148 10.1354021658 5.7050978342
PWK/PhJ m 11.9296 0.9890435586 13.9108923293 9.9483076707
WSB/EiJ f 1.9353333333 1.2768497437 4.4931707317 -0.6225040651
WSB/EiJ m 1.9364 0.9890435586 3.9176923293 -0.0448923293


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 8.4859 0.9251655342 10.3392292698 6.6325707302
A/J both 6.696775 0.7417826689 8.182744247 5.210805753
C57BL/6J both 8.588625 0.8445567208 10.2804754126 6.8967745874
CAST/EiJ both 2.18095 0.9251655342 4.0342792698 0.3276207302
DBA/2J both 13.1119 0.6993594072 14.5128852415 11.7109147585
NOD/ShiLtJ both 7.1049 0.605663013 8.3181888095 5.8916111905
PWK/PhJ both 9.924925 0.7417826689 11.410894247 8.438955753
WSB/EiJ both 1.9358666667 0.807550684 3.5535850793 0.318148254




  GWAS USING LINEAR MIXED MODELS