Project measure / variable:   Auwerx2   bw_14wks_MRI_CD

ID, description, units MPD:114559   bw_14wks_MRI_CD   body weight measured by EchoMRI   [g]  CD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 14wks
Procedure body weight
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  STRAIN COMPARISON PLOT
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Auwerx2 - body weight measured by EchoMRI CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means23.317   g 28.082   g
Median of the strain means22.076   g 27.09   g
SD of the strain means± 11.941 ± 10.841
Coefficient of variation (CV)0.5121 0.3861
Min–max range of strain means11.26   –   52.52   g 14.594   –   52.31   g
Mean sample size per strain4.0   mice 4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 444.1061 444.1061 120.4654 < 0.0001
strain 7 7739.6794 1105.6685 299.9166 < 0.0001
sex:strain 7 153.2128 21.8875 5.9371 < 0.0001
Residuals 59 217.5086 3.6866


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 22.076 0.91855   5 0.41079 0.0416 21.28, 23.57 -0.1
129S1/SvImJ m 25.85 1.3219   5 0.59117 0.0511 24.37, 27.37 -0.21
A/J f 24.756 1.2009   5 0.53707 0.0485 23.69, 26.8 0.12
A/J m 27.09 1.1973   5 0.53546 0.0442 25.39, 28.71 -0.09
C57BL/6J f 21.14 1.6539   5 0.73964 0.0782 19.09, 23.13 -0.18
C57BL/6J m 29.116 1.6314   5 0.72958 0.056 26.8, 30.8 0.1
CAST/EiJ f 13.11 0.0   1   0.0 0.0 13.11, 13.11 -0.85
CAST/EiJ m 16.303 1.075   3 0.62065 0.0659 15.14, 17.26 -1.09
DBA/2J f 24.478 1.5571   5 0.69635 0.0636 22.87, 26.81 0.1
DBA/2J m 32.204 2.5269   5 1.13 0.0785 29.9, 36.49 0.38
NOD/ShiLtJ f 22.493 0.40723   3 0.23511 0.0181 22.21, 22.96 -0.07
NOD/ShiLtJ m 29.656 0.52918   5 0.23666 0.0178 28.87, 30.32 0.15
NZO/HlLtJ f 52.52 2.9644   4 1.4822 0.0564 50.23, 56.65 2.45
NZO/HlLtJ m 52.31 4.9105   5 2.196 0.0939 46.85, 59.0 2.23
PWK/PhJ f 18.024 1.1891   5 0.53178 0.066 16.72, 19.66 -0.44
PWK/PhJ m 25.616 1.2346   5 0.55213 0.0482 24.83, 27.68 -0.23
WSB/EiJ f 11.26 0.15133   3 0.08737 0.0134 11.09, 11.38 -1.01
WSB/EiJ m 14.594 0.82914   5 0.3708 0.0568 13.46, 15.64 -1.24


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 22.076 0.8586718295 23.7941983621 20.3578016379
129S1/SvImJ m 25.85 0.8586718295 27.5681983621 24.1318016379
A/J f 24.756 0.8586718295 26.4741983621 23.0378016379
A/J m 27.09 0.8586718295 28.8081983621 25.3718016379
C57BL/6J f 21.14 0.8586718295 22.8581983621 19.4218016379
C57BL/6J m 29.116 0.8586718295 30.8341983621 27.3978016379
DBA/2J f 24.478 0.8586718295 26.1961983621 22.7598016379
DBA/2J m 32.204 0.8586718295 33.9221983621 30.4858016379
NOD/ShiLtJ f 22.4933333333 1.1085405651 24.7115178806 20.2751487861
NOD/ShiLtJ m 29.656 0.8586718295 31.3741983621 27.9378016379
NZO/HlLtJ f 52.515 0.9600242905 54.4360041682 50.5939958318
NZO/HlLtJ m 52.31 0.8586718295 54.0281983621 50.5918016379
PWK/PhJ f 18.024 0.8586718295 19.7421983621 16.3058016379
PWK/PhJ m 25.616 0.8586718295 27.3341983621 23.8978016379
WSB/EiJ f 11.26 1.1085405651 13.4781845473 9.0418154527
WSB/EiJ m 14.594 0.8586718295 16.3121983621 12.8758016379


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 23.963 0.6071726734 25.1779497132 22.7480502868
A/J both 25.923 0.6071726734 27.1379497132 24.7080502868
C57BL/6J both 25.128 0.6071726734 26.3429497132 23.9130502868
DBA/2J both 28.341 0.6071726734 29.5559497132 27.1260502868
NOD/ShiLtJ both 26.0746666667 0.7011026129 27.4775697547 24.6717635787
NZO/HlLtJ both 52.4125 0.6440038721 53.7011487716 51.1238512284
PWK/PhJ both 21.82 0.6071726734 23.0349497132 20.6050502868
WSB/EiJ both 12.927 0.7011026129 14.329903088 11.524096912




  GWAS USING LINEAR MIXED MODELS