Project measure / variable:   Auwerx2   bw_16wks_HFD

ID, description, units MPD:114548   bw_16wks_HFD   body weight at 16 wks of age   [g]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 16wks
Procedure body weight
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  STRAIN COMPARISON PLOT
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Auwerx2 - body weight at 16 wks of age HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means29.084   g 34.475   g
Median of the strain means23.943   g 32.73   g
SD of the strain means± 17.756 ± 16.576
Coefficient of variation (CV)0.6105 0.4808
Min–max range of strain means12.707   –   72.24   g 16.462   –   72.22   g
Mean sample size per strain4.4   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 566.7547 566.7547 88.2154 < 0.0001
strain 7 4028.0388 575.4341 89.5663 < 0.0001
sex:strain 7 298.8711 42.6959 6.6456 < 0.0001
Residuals 52 334.0828 6.4247


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 23.298 1.3917   5 0.62239 0.0597 21.5, 25.04 -0.33
129S1/SvImJ m 32.73 1.994   2   1.41 0.0609 31.32, 34.14 -0.11
A/J f 23.93 2.0351   4 1.0176 0.085 21.77, 26.61 -0.29
A/J m 29.23 1.7252   5 0.77154 0.059 26.92, 31.03 -0.32
C57BL/6J f 23.943 3.2533   3 1.8783 0.1359 21.23, 27.55 -0.29
C57BL/6J m 40.435 2.5803   4 1.2901 0.0638 37.03, 42.72 0.36
CAST/EiJ f 13.704 0.75421   5 0.33729 0.055 12.83, 14.82 -0.87
CAST/EiJ m 17.83 1.3859   2   0.98 0.0777 16.85, 18.81 -1.0
DBA/2J f 35.952 4.7192   5 2.1105 0.1313 29.87, 41.22 0.39
DBA/2J m 41.402 1.8889   5 0.84473 0.0456 39.81, 44.36 0.42
NOD/ShiLtJ f 31.07 3.6303   6 1.4821 0.1168 26.57, 36.92 0.11
NOD/ShiLtJ m 32.952 1.7164   5 0.76758 0.0521 31.5, 35.46 -0.09
NZO/HlLtJ f 72.24 2.012   5 0.89977 0.0279 70.12, 74.93 2.43
NZO/HlLtJ m 72.22 0.0   1   0.0 0.0 72.22, 72.22 2.28
PWK/PhJ f 24.91 2.8735   4 1.4367 0.1154 20.85, 27.62 -0.24
PWK/PhJ m 27.018 3.2186   5 1.4394 0.1191 22.74, 30.94 -0.45
WSB/EiJ f 12.707 0.83189   3 0.48029 0.0655 11.75, 13.26 -0.92
WSB/EiJ m 16.462 1.0079   5 0.45075 0.0612 15.29, 17.97 -1.09


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 23.298 1.1335492818 25.5726330448 21.0233669552
129S1/SvImJ m 32.73 1.7922987853 36.3265106313 29.1334893687
A/J f 23.93 1.267346625 26.473117056 21.386882944
A/J m 29.23 1.1335492818 31.5046330448 26.9553669552
C57BL/6J f 23.9433333333 1.4634058302 26.8798719671 21.0067946996
C57BL/6J m 40.435 1.267346625 42.978117056 37.891882944
CAST/EiJ f 13.704 1.1335492818 15.9786330448 11.4293669552
CAST/EiJ m 17.83 1.7922987853 21.4265106313 14.2334893687
DBA/2J f 35.952 1.1335492818 38.2266330448 33.6773669552
DBA/2J m 41.402 1.1335492818 43.6766330448 39.1273669552
NOD/ShiLtJ f 31.07 1.0347841862 33.1464463811 28.9935536189
NOD/ShiLtJ m 32.952 1.1335492818 35.2266330448 30.6773669552
PWK/PhJ f 24.91 1.267346625 27.453117056 22.366882944
PWK/PhJ m 27.018 1.1335492818 29.2926330448 24.7433669552
WSB/EiJ f 12.7066666667 1.4634058302 15.6432053004 9.7701280329
WSB/EiJ m 16.462 1.1335492818 18.7366330448 14.1873669552


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 28.014 1.0603382609 30.1417243836 25.8862756164
A/J both 26.58 0.8501619614 28.2859747836 24.8740252164
C57BL/6J both 32.1891666667 0.9679519735 34.1315044017 30.2468289316
CAST/EiJ both 15.767 1.0603382609 17.8947243836 13.6392756164
DBA/2J both 38.677 0.801540384 40.2854084507 37.0685915493
NOD/ShiLtJ both 32.011 0.7674164916 33.550933851 30.471066149
PWK/PhJ both 25.964 0.8501619614 27.6699747836 24.2580252164
WSB/EiJ both 14.5843333333 0.9255391129 16.4415634373 12.7271032294




  GWAS USING LINEAR MIXED MODELS