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Project measure / variable:   Auwerx2   bw_12wks_HFD

ID, description, units MPD:114540   bw_12wks_HFD   body weight at 12 wks of age   [g]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 12wks
Procedure body weight
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  STRAIN COMPARISON PLOT
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Auwerx2 - body weight at 12 wks of age HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means25.822   g 31.303   g
Median of the strain means22.21   g 31.31   g
SD of the strain means± 13.933 ± 14.566
Coefficient of variation (CV)0.5396 0.4653
Min–max range of strain means12.98   –   59.79   g 15.24   –   64.77   g
Mean sample size per strain4.4   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 478.83 478.83 107.3647 < 0.0001
strain 7 2786.4578 398.0654 89.2554 < 0.0001
sex:strain 7 152.605 21.8007 4.8882 0.0003
Residuals 52 231.9119 4.4598


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 22.21 1.1813   5 0.52831 0.0532 20.73, 23.98 -0.26
129S1/SvImJ m 31.31 0.89095   2   0.63 0.0285 30.68, 31.94 0.0
A/J f 21.718 1.6256   4 0.81279 0.0749 20.6, 24.13 -0.29
A/J m 27.398 1.6727   5 0.74803 0.0611 24.75, 29.22 -0.27
C57BL/6J f 23.013 1.3987   3 0.80755 0.0608 21.89, 24.58 -0.2
C57BL/6J m 33.535 1.9655   4 0.98277 0.0586 31.66, 36.27 0.15
CAST/EiJ f 12.98 0.81514   5 0.36454 0.0628 11.96, 14.19 -0.92
CAST/EiJ m 16.65 0.16971   2   0.12 0.0102 16.53, 16.77 -1.01
DBA/2J f 28.752 1.9619   5 0.8774 0.0682 25.71, 30.42 0.21
DBA/2J m 37.048 3.4899   5 1.5607 0.0942 32.4, 41.67 0.39
NOD/ShiLtJ f 29.24 3.5512   6 1.4498 0.1215 26.27, 35.78 0.25
NOD/ShiLtJ m 31.63 1.7268   5 0.77223 0.0546 29.62, 34.0 0.02
NZO/HlLtJ f 59.79 2.3944   5 1.0708 0.04 57.8, 63.8 2.44
NZO/HlLtJ m 64.77 0.0   1   0.0 0.0 64.77, 64.77 2.3
PWK/PhJ f 21.393 2.28   4 1.14 0.1066 18.1, 23.26 -0.32
PWK/PhJ m 24.148 2.7318   5 1.2217 0.1131 19.64, 26.23 -0.49
WSB/EiJ f 13.303 0.33322   3 0.19238 0.025 13.0, 13.66 -0.9
WSB/EiJ m 15.24 0.93013   5 0.41597 0.061 14.26, 16.25 -1.1


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 22.21 0.9444410299 24.1051595752 20.3148404248
129S1/SvImJ m 31.31 1.4932923851 34.3065103936 28.3134896064
A/J f 21.7175 1.0559171718 23.8363528192 19.5986471808
A/J m 27.398 0.9444410299 29.2931595752 25.5028404248
C57BL/6J f 23.0133333333 1.2192681268 25.4599738244 20.5666928422
C57BL/6J m 33.535 1.0559171718 35.6538528192 31.4161471808
CAST/EiJ f 12.98 0.9444410299 14.8751595752 11.0848404248
CAST/EiJ m 16.65 1.4932923851 19.6465103936 13.6534896064
DBA/2J f 28.752 0.9444410299 30.6471595752 26.8568404248
DBA/2J m 37.048 0.9444410299 38.9431595752 35.1528404248
NOD/ShiLtJ f 29.24 0.8621527605 30.9700360824 27.5099639176
NOD/ShiLtJ m 31.63 0.9444410299 33.5251595752 29.7348404248
PWK/PhJ f 21.3925 1.0559171718 23.5113528192 19.2736471808
PWK/PhJ m 24.148 0.9444410299 26.0431595752 22.2528404248
WSB/EiJ f 13.3033333333 1.2192681268 15.7499738244 10.8566928422
WSB/EiJ m 15.24 0.9444410299 17.1351595752 13.3448404248


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 26.76 0.883443689 28.5327594559 24.9872405441
A/J both 24.55775 0.7083307724 25.9791196814 23.1363803186
C57BL/6J both 28.2741666667 0.8064700612 29.8924672384 26.6558660949
CAST/EiJ both 14.815 0.883443689 16.5877594559 13.0422405441
DBA/2J both 32.9 0.6678206567 34.2400801871 31.5599198129
NOD/ShiLtJ both 30.435 0.6393895998 31.7180290977 29.1519709023
PWK/PhJ both 22.77025 0.7083307724 24.1916196814 21.3488803186
WSB/EiJ both 14.2716666667 0.7711328718 15.8190579802 12.7242753532




  GWAS USING LINEAR MIXED MODELS