Project measure / variable:   Auwerx2   bw_8wks_HFD

ID, description, units MPD:114532   bw_8wks_HFD   body weight at 8 wks of age   [g]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 8wks
Procedure body weight
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  STRAIN COMPARISON PLOT
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Auwerx2 - body weight at 8 wks of age HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means19.589   g 24.491   g
Median of the strain means19.29   g 24.465   g
SD of the strain means± 7.5932 ± 9.6903
Coefficient of variation (CV)0.3876 0.3957
Min–max range of strain means10.383   –   36.614   g 13.13   –   46.13   g
Mean sample size per strain4.4   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 246.437 246.437 112.1517 < 0.0001
strain 7 1447.4263 206.7752 94.1019 < 0.0001
sex:strain 7 51.0341 7.2906 3.3179 0.0054
Residuals 52 114.2624 2.1974


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 20.426 1.9984   5 0.89372 0.0978 17.4, 22.71 0.11
129S1/SvImJ m 27.13 2.4466   2   1.73 0.0902 25.4, 28.86 0.27
A/J f 19.29 0.90104   4 0.45052 0.0467 18.22, 20.4 -0.04
A/J m 22.918 1.1705   5 0.52345 0.0511 21.59, 24.2 -0.16
C57BL/6J f 18.313 0.12897   3 0.07446 0.007 18.17, 18.42 -0.17
C57BL/6J m 24.465 1.3247   4 0.66233 0.0541 22.48, 25.21 0.0
CAST/EiJ f 12.178 0.64828   5 0.28992 0.0532 11.57, 13.24 -0.98
CAST/EiJ m 15.685 0.10607   2   0.075 0.0068 15.61, 15.76 -0.91
DBA/2J f 21.47 1.3465   5 0.60219 0.0627 20.34, 23.22 0.25
DBA/2J m 28.21 2.3196   5 1.0373 0.0822 24.87, 31.21 0.38
NOD/ShiLtJ f 22.317 2.3915   6 0.97634 0.1072 19.06, 26.48 0.36
NOD/ShiLtJ m 25.476 1.1749   5 0.52545 0.0461 24.29, 27.23 0.1
NZO/HlLtJ f 36.614 2.7527   5 1.2311 0.0752 34.21, 40.36 2.24
NZO/HlLtJ m 46.13 0.0   1   0.0 0.0 46.13, 46.13 2.23
PWK/PhJ f 15.307 1.2368   4 0.6184 0.0808 14.48, 17.11 -0.56
PWK/PhJ m 17.272 1.3027   5 0.5826 0.0754 14.98, 18.19 -0.74
WSB/EiJ f 10.383 0.66711   3 0.38516 0.0642 9.64, 10.93 -1.21
WSB/EiJ m 13.13 0.74766   5 0.33437 0.0569 12.42, 14.35 -1.17


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 20.426 0.6629258331 21.7562580051 19.0957419949
129S1/SvImJ m 27.13 1.0481777763 29.2333225859 25.0266774141
A/J f 19.29 0.7411736135 20.7772736635 17.8027263365
A/J m 22.918 0.6629258331 24.2482580051 21.5877419949
C57BL/6J f 18.3133333333 0.8558335705 20.0306890333 16.5959776334
C57BL/6J m 24.465 0.7411736135 25.9522736635 22.9777263365
CAST/EiJ f 12.178 0.6629258331 13.5082580051 10.8477419949
CAST/EiJ m 15.685 1.0481777763 17.7883225859 13.5816774141
DBA/2J f 21.47 0.6629258331 22.8002580051 20.1397419949
DBA/2J m 28.21 0.6629258331 29.5402580051 26.8797419949
NOD/ShiLtJ f 22.3166666667 0.6051657213 23.5310205278 21.1023128055
NOD/ShiLtJ m 25.476 0.6629258331 26.8062580051 24.1457419949
PWK/PhJ f 15.3075 0.7411736135 16.7947736635 13.8202263365
PWK/PhJ m 17.272 0.6629258331 18.6022580051 15.9417419949
WSB/EiJ f 10.3833333333 0.8558335705 12.1006890333 8.6659776334
WSB/EiJ m 13.13 0.6629258331 14.4602580051 11.7997419949


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 23.778 0.6201103351 25.0223424228 22.5336575772
A/J both 21.104 0.4971943749 22.1016935038 20.1063064962
C57BL/6J both 21.3891666667 0.5660806978 22.5250906903 20.253242643
CAST/EiJ both 13.9315 0.6201103351 15.1758424228 12.6871575772
DBA/2J both 24.84 0.468759352 25.7806344561 23.8993655439
NOD/ShiLtJ both 23.8963333333 0.4488029107 24.7969222601 22.9957444066
PWK/PhJ both 16.28975 0.4971943749 17.2874435038 15.2920564962
WSB/EiJ both 11.7566666667 0.5412766762 12.8428177796 10.6705155538




  GWAS USING LINEAR MIXED MODELS