Project measure / variable:   Schoonjans1   IsoDCA_liver_HFD

ID, description, units MPD:112832   IsoDCA_liver_HFD   bile acid isodeoxycholic acid amount in liver, at 29 wks   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 29wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid isodeoxycholic acid amount in liver, at 29 wks HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means0.00306046   ng/mL
Median of the strain means0.00332564   ng/mL
SD of the strain means± 0.00092893
Coefficient of variation (CV)0.3035
Min–max range of strain means0.00095043   –   0.00476072   ng/mL
Mean sample size per strain4.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 0.0001 0.0 0.1639 1.0
Residuals 141 0.0032 0.0


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.00389944 0.00493074   5 0.00220509 1.2645 0.00145874, 0.01271 0.9
BXD100 m 0.00095737 0.00016819   7 6.357e-05 0.1757 0.00065089, 0.00110558 -2.26
BXD11 m 0.00476072 0.00566532   3 0.00327087 1.19 0.00133562, 0.0113 1.83
BXD12 m 0.00121655 0.00022377   4 0.00011189 0.1839 0.00098529, 0.00151768 -1.98
BXD27 m 0.00348257 0.00518512   5 0.00231886 1.4889 0.00096154, 0.01275 0.45
BXD32 m 0.00118109 0.00033367   4 0.00016683 0.2825 0.00089374, 0.00165672 -2.02
BXD34 m 0.00404774 0.0058953   4 0.00294765 1.4564 0.0010472, 0.01289 1.06
BXD39 m 0.00355204 0.00511484   5 0.00228743 1.44 0.00113793, 0.0127 0.53
BXD40 m 0.00339689 0.00506359   5 0.00226451 1.4907 0.00096923, 0.01245 0.36
BXD43 m 0.00339238 0.00508371   5 0.0022735 1.4986 0.00088235, 0.01248 0.36
BXD45 m 0.00348262 0.00509895   5 0.00228032 1.4641 0.00105865, 0.0126 0.45
BXD48 m 0.00341469 0.00514658   5 0.00230162 1.5072 0.00101493, 0.01262 0.38
BXD48a m 0.00332644 0.00503885   5 0.00225344 1.5148 0.0010402, 0.01234 0.29
BXD49 m 0.00346008 0.00531698   5 0.00237782 1.5367 0.00096919, 0.01297 0.43
BXD51 m 0.00332484 0.00519634   5 0.00232388 1.5629 0.00093287, 0.01262 0.28
BXD53 m 0.00325269 0.00501992   5 0.00224497 1.5433 0.000855, 0.01223 0.21
BXD55 m 0.00333048 0.00508781   5 0.00227534 1.5277 0.00094321, 0.01243 0.29
BXD6 m 0.00375466 0.0050236   5 0.00224662 1.338 0.00114343, 0.01271 0.75
BXD62 m 0.00335976 0.00510528   5 0.00228315 1.5195 0.00091226, 0.01249 0.32
BXD63 m 0.00335746 0.00520287   5 0.00232679 1.5496 0.00075453, 0.01266 0.32
BXD64 m 0.00332764 0.00517859   5 0.00231594 1.5562 0.00089021, 0.01259 0.29
BXD66 m 0.00357013 0.00503433   9 0.00167811 1.4101 0.0008209, 0.01252 0.55
BXD67 m 0.00329222 0.00516495   5 0.00230983 1.5688 0.00082583, 0.01253 0.25
BXD69 m 0.00335057 0.00519371   5 0.0023227 1.5501 0.0009375, 0.01264 0.31
BXD73 m 0.00330097 0.00518335   5 0.00231806 1.5702 0.00083499, 0.01257 0.26
BXD75 m 0.00097043 8.57e-05   4 4.285e-05 0.0883 0.00088496, 0.00105 -2.25
BXD77 m 0.00329237 0.00528811   5 0.00236491 1.6062 0.00079268, 0.01275 0.25
BXD79 m 0.00323299 0.00519212   5 0.00232198 1.606 0.00079412, 0.01252 0.19
BXD8 m 0.00144897 0.00033816   4 0.00016908 0.2334 0.0011747, 0.001935 -1.73
BXD81 m 0.00326442 0.00516863   5 0.00231148 1.5833 0.00089641, 0.01251 0.22
BXD84 m 0.00330056 0.00519877   5 0.00232496 1.5751 0.00092537, 0.0126 0.26
BXD87 m 0.003299 0.00508245   5 0.00227294 1.5406 0.0009328, 0.01239 0.26
BXD89 m 0.00327615 0.00512369   5 0.00229139 1.5639 0.00082335, 0.01244 0.23
BXD90 m 0.00095043 6.355e-05   3 3.669e-05 0.0669 0.00087719, 0.00099099 -2.27
C57BL/6J m 0.00321816 0.00504372   5 0.00225562 1.5673 0.00089286, 0.01224 0.17
DBA/2J m 0.00313113 0.00529271   5 0.00236697 1.6904 0.00037165, 0.01259 0.08


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.00389944 0.0021385259 0.0081271593 -0.0003282793
BXD100 m 0.0009573714 0.0018073843 0.0045304463 -0.0026157035
BXD11 m 0.0047607167 0.0027608251 0.0102186788 -0.0006972454
BXD12 m 0.0012165525 0.0023909447 0.0059432863 -0.0035101813
BXD27 m 0.003482572 0.0021385259 0.0077102913 -0.0007451473
BXD32 m 0.001181085 0.0023909447 0.0059078188 -0.0035456488
BXD34 m 0.0040477425 0.0023909447 0.0087744763 -0.0006789913
BXD39 m 0.00355204 0.0021385259 0.0077797593 -0.0006756793
BXD40 m 0.003396894 0.0021385259 0.0076246133 -0.0008308253
BXD43 m 0.003392384 0.0021385259 0.0076201033 -0.0008353353
BXD45 m 0.003482624 0.0021385259 0.0077103433 -0.0007450953
BXD48 m 0.00341469 0.0021385259 0.0076424093 -0.0008130293
BXD48a m 0.00332644 0.0021385259 0.0075541593 -0.0009012793
BXD49 m 0.003460078 0.0021385259 0.0076877973 -0.0007676413
BXD51 m 0.00332484 0.0021385259 0.0075525593 -0.0009028793
BXD53 m 0.003252688 0.0021385259 0.0074804073 -0.0009750313
BXD55 m 0.003330478 0.0021385259 0.0075581973 -0.0008972413
BXD6 m 0.003754656 0.0021385259 0.0079823753 -0.0004730633
BXD62 m 0.003359758 0.0021385259 0.0075874773 -0.0008679613
BXD63 m 0.003357458 0.0021385259 0.0075851773 -0.0008702613
BXD64 m 0.00332764 0.0021385259 0.0075553593 -0.0009000793
BXD66 m 0.0035701333 0.0015939631 0.0067212892 0.0004189775
BXD67 m 0.00329222 0.0021385259 0.0075199393 -0.0009354993
BXD69 m 0.00335057 0.0021385259 0.0075782893 -0.0008771493
BXD73 m 0.003300974 0.0021385259 0.0075286933 -0.0009267453
BXD75 m 0.0009704275 0.0023909447 0.0056971613 -0.0037563063
BXD77 m 0.003292374 0.0021385259 0.0075200933 -0.0009353453
BXD79 m 0.00323299 0.0021385259 0.0074607093 -0.0009947293
BXD8 m 0.0014489725 0.0023909447 0.0061757063 -0.0032777613
BXD81 m 0.003264422 0.0021385259 0.0074921413 -0.0009632973
BXD84 m 0.00330056 0.0021385259 0.0075282793 -0.0009271593
BXD87 m 0.003299 0.0021385259 0.0075267193 -0.0009287193
BXD89 m 0.003276152 0.0021385259 0.0075038713 -0.0009515673
BXD90 m 0.0009504333 0.0027608251 0.0064083954 -0.0045075288
C57BL/6J m 0.00321816 0.0021385259 0.0074458793 -0.0010095593
DBA/2J m 0.003131128 0.0021385259 0.0073588473 -0.0010965913




  GWAS USING LINEAR MIXED MODELS