Project measure / variable:   Schoonjans1   TaMCA_feces_CD

ID, description, units MPD:112788   TaMCA_feces_CD   bile acid tauro-α-muricholic acid in feces, at 24 wks   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 24wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid tauro-α-muricholic acid in feces, at 24 wks CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means0.49698   ng/mL
Median of the strain means0.24435   ng/mL
SD of the strain means± 0.68343
Coefficient of variation (CV)1.3752
Min–max range of strain means0.08223   –   2.9387   ng/mL
Mean sample size per strain4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 76.6414 2.1898 1.5562 0.0388
Residuals 135 189.959 1.4071


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.19483 0.08087   5 0.03617 0.4151 0.12231, 0.32014 -0.44
BXD100 m 0.42217 0.1149   5 0.05138 0.2722 0.29169, 0.59801 -0.11
BXD11 m 1.1521 0.37246   4 0.18623 0.3233 0.75944, 1.6425 0.96
BXD12 m 0.3427 0.18159   4 0.09079 0.5299 0.18474, 0.60452 -0.23
BXD27 m 0.95388 0.58362   4 0.29181 0.6118 0.44928, 1.7681 0.67
BXD32 m 2.5468 4.7293   4 2.3647 1.8569 0.15079, 9.6407 3.0
BXD34 m 0.1677 0.06401   4 0.032 0.3817 0.09358, 0.24269 -0.48
BXD39 m 0.20027 0.09285   5 0.04153 0.4637 0.13131, 0.35542 -0.43
BXD40 m 0.12602 0.02829   5 0.01265 0.2245 0.09875, 0.1697 -0.54
BXD43 m 0.1744 0.10881   4 0.05441 0.6239 0.07973, 0.32921 -0.47
BXD45 m 0.43723 0.48724   3 0.28131 1.1144 0.08915, 0.99407 -0.09
BXD48 m 0.28229 0.27527   5 0.1231 0.9751 0.10896, 0.76333 -0.31
BXD48a m 0.39971 0.10997   4 0.05499 0.2751 0.32109, 0.5596 -0.14
BXD49 m 0.12887 0.023   5 0.01029 0.1785 0.11085, 0.16649 -0.54
BXD51 m 0.24056 0.06037   5 0.027 0.251 0.16936, 0.31396 -0.38
BXD53 m 0.18923 0.09912   5 0.04433 0.5238 0.07984, 0.33467 -0.45
BXD55 m 0.21636 0.04583   5 0.0205 0.2118 0.16014, 0.28557 -0.41
BXD6 m 0.24406 0.04427   5 0.0198 0.1814 0.193, 0.29395 -0.37
BXD62 m 0.33042 0.21398   5 0.09569 0.6476 0.17192, 0.69551 -0.24
BXD63 m 0.08223 0.03851   5 0.01722 0.4683 0.05252, 0.14298 -0.61
BXD64 m 0.22105 0.06878   5 0.03076 0.3111 0.1797, 0.34272 -0.4
BXD66 m 0.33467 0.20742   5 0.09276 0.6198 0.1553, 0.66723 -0.24
BXD67 m 0.1551 0.05459   4 0.02729 0.3519 0.11691, 0.23606 -0.5
BXD69 m 0.24464 0.10595   5 0.04738 0.4331 0.14839, 0.36991 -0.37
BXD73 m 0.23615 0.15476   5 0.06921 0.6553 0.1008, 0.4899 -0.38
BXD75 m 0.25205 0.15568   5 0.06962 0.6177 0.12569, 0.50997 -0.36
BXD77 m 0.27001 0.13748   5 0.06148 0.5092 0.14961, 0.49839 -0.33
BXD79 m 0.32571 0.15503   5 0.06933 0.476 0.15367, 0.49929 -0.25
BXD8 m 0.5516 0.35876   5 0.16044 0.6504 0.22332, 1.079 0.08
BXD81 m 0.21191 0.05685   5 0.02543 0.2683 0.15842, 0.30132 -0.42
BXD84 m 0.10419 0.02368   5 0.01059 0.2273 0.0697, 0.13312 -0.57
BXD87 m 0.1498 0.02098   5 0.00938031 0.14 0.12113, 0.17398 -0.51
BXD89 m 0.63574 0.36742   5 0.16431 0.5779 0.35055, 1.1954 0.2
BXD90 m 2.9387 5.1481   5 2.3023 1.7519 0.26448, 12.084 3.57
C57BL/6J m 0.12061 0.06005   6 0.02452 0.4979 0.07312, 0.24024 -0.55
DBA/2J m 2.3074 1.7587   5 0.7865 0.7622 0.32301, 4.4623 2.65


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.194826 0.5304909927 1.2439739394 -0.8543219394
BXD100 m 0.42217 0.5304909927 1.4713179394 -0.6269779394
BXD11 m 1.15211 0.5931069606 2.3250930555 -0.0208730555
BXD12 m 0.3426975 0.5931069606 1.5156805555 -0.8302855555
BXD27 m 0.9538775 0.5931069606 2.1268605555 -0.2191055555
BXD32 m 2.5468225 0.5931069606 3.7198055555 1.3738394445
BXD34 m 0.1677 0.5931069606 1.3406830555 -1.0052830555
BXD39 m 0.200266 0.5304909927 1.2494139394 -0.8488819394
BXD40 m 0.126022 0.5304909927 1.1751699394 -0.9231259394
BXD43 m 0.1744 0.5931069606 1.3473830555 -0.9985830555
BXD45 m 0.43723 0.6848609267 1.7916741657 -0.9172141657
BXD48 m 0.28229 0.5304909927 1.3314379394 -0.7668579394
BXD48a m 0.3997075 0.5931069606 1.5726905555 -0.7732755555
BXD49 m 0.128868 0.5304909927 1.1780159394 -0.9202799394
BXD51 m 0.240558 0.5304909927 1.2897059394 -0.8085899394
BXD53 m 0.18923 0.5304909927 1.2383779394 -0.8599179394
BXD55 m 0.216356 0.5304909927 1.2655039394 -0.8327919394
BXD6 m 0.244064 0.5304909927 1.2932119394 -0.8050839394
BXD62 m 0.330418 0.5304909927 1.3795659394 -0.7187299394
BXD63 m 0.08223 0.5304909927 1.1313779394 -0.9669179394
BXD64 m 0.221052 0.5304909927 1.2701999394 -0.8280959394
BXD66 m 0.33467 0.5304909927 1.3838179394 -0.7144779394
BXD67 m 0.1551025 0.5931069606 1.3280855555 -1.0178805555
BXD69 m 0.244642 0.5304909927 1.2937899394 -0.8045059394
BXD73 m 0.236152 0.5304909927 1.2852999394 -0.8129959394
BXD75 m 0.252052 0.5304909927 1.3011999394 -0.7970959394
BXD77 m 0.270008 0.5304909927 1.3191559394 -0.7791399394
BXD79 m 0.325708 0.5304909927 1.3748559394 -0.7234399394
BXD8 m 0.551602 0.5304909927 1.6007499394 -0.4975459394
BXD81 m 0.211912 0.5304909927 1.2610599394 -0.8372359394
BXD84 m 0.104188 0.5304909927 1.1533359394 -0.9449599394
BXD87 m 0.149802 0.5304909927 1.1989499394 -0.8993459394
BXD89 m 0.635736 0.5304909927 1.6848839394 -0.4134119394
BXD90 m 2.938658 0.5304909927 3.9878059394 1.8895100606
C57BL/6J m 0.120615 0.4842698054 1.0783516543 -0.8371216543
DBA/2J m 2.307372 0.5304909927 3.3565199394 1.2582240606




  GWAS USING LINEAR MIXED MODELS