Project measure / variable:   Schoonjans1   MCA_plasma_t60_CD

ID, description, units MPD:112734   MCA_plasma_t60_CD   plasma bile acid γ-muricholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   13 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid γ-muricholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested13 strains
Mean of the strain means2.1848   ng/mL
Median of the strain means1.546   ng/mL
SD of the strain means± 1.2349
Coefficient of variation (CV)0.5652
Min–max range of strain means1.24   –   5.004   ng/mL
Mean sample size per strain1.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 5 21.9814 4.3963 14.3506 0.0002
Residuals 11 3.3698 0.3063


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD100 m 2.074 0.0   1   0.0 0.0 2.074, 2.074 -0.09
BXD12 m 4.286 0.0   1   0.0 0.0 4.286, 4.286 1.7
BXD32 m 3.238 0.0   1   0.0 0.0 3.238, 3.238 0.85
BXD40 m 2.107 0.49639   2   0.351 0.2356 1.756, 2.458 -0.06
BXD45 m 1.382 0.0   1   0.0 0.0 1.382, 1.382 -0.65
BXD48 m 1.343 0.13718   2   0.097 0.1021 1.246, 1.44 -0.68
BXD48a m 1.24 0.0   1   0.0 0.0 1.24, 1.24 -0.77
BXD53 m 1.242 0.0   1   0.0 0.0 1.242, 1.242 -0.76
BXD6 m 2.162 0.69166   3 0.39933 0.3199 1.416, 2.782 -0.02
BXD66 m 1.4055 0.07999   4 0.03999 0.0569 1.336, 1.52 -0.63
BXD75 m 1.3735 0.17168   4 0.08584 0.125 1.236, 1.606 -0.66
BXD77 m 5.004 1.4284   2   1.01 0.2854 3.994, 6.014 2.28
BXD90 m 1.546 0.0   1   0.0 0.0 1.546, 1.546 -0.52


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD40 m 2.107 0.3913748494 2.9684102355 1.2455897645
BXD48 m 1.343 0.3913748494 2.2044102355 0.4815897645
BXD6 m 2.162 0.3195562264 2.8653385121 1.4586614879
BXD66 m 1.4055 0.27674381 2.0146090189 0.7963909811
BXD75 m 1.3735 0.27674381 1.9826090189 0.7643909811
BXD77 m 5.004 0.3913748494 5.8654102355 4.1425897645




  GWAS USING LINEAR MIXED MODELS