Project measure / variable:   Schoonjans1   wMCA_plasma_t30_HFD

ID, description, units MPD:112717   wMCA_plasma_t30_HFD   plasma bile acid ω-muricholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid ω-muricholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means47.515   ng/mL
Median of the strain means32.221   ng/mL
SD of the strain means± 37.547
Coefficient of variation (CV)0.7902
Min–max range of strain means5.6401   –   164.9   ng/mL
Mean sample size per strain4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 192285.4082 5493.8688 1.9744 0.0036
Residuals 121 336692.976 2782.5866


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 25.332 12.855   5 5.749 0.5075 10.03, 42.041 -0.59
BXD100 m 12.79 8.1195   9 2.7065 0.6349 4.578, 28.262 -0.92
BXD11 m 164.9 212.6   3 122.8 1.2892 33.22, 410.2 3.13
BXD12 m 135.5 185.9   4 92.96 1.3718 11.59, 411.5 2.34
BXD27 m 18.604 20.099   5 8.9883 1.0804 6.036, 53.81 -0.77
BXD32 m 15.91 8.7959   4 4.3979 0.5529 8.126, 27.712 -0.84
BXD34 m 44.137 16.79   4 8.3951 0.3804 30.208, 68.23 -0.09
BXD39 m 25.091 5.164   3 2.9814 0.2058 19.206, 28.864 -0.6
BXD40 m 136.8 90.55   4 45.276 0.6621 68.73, 264.0 2.38
BXD43 m 29.007 5.5845   5 2.4975 0.1925 19.56, 34.332 -0.49
BXD45 m 73.21 19.598   5 8.7644 0.2677 51.16, 95.91 0.68
BXD48 m 27.988 5.3077   5 2.3737 0.1896 22.968, 36.908 -0.52
BXD48a m 35.434 14.831   4 7.4156 0.4186 24.884, 57.36 -0.32
BXD49 m 76.92 67.87   5 30.351 0.8824 29.974, 191.7 0.78
BXD51 m 17.692 5.713   3 3.2984 0.3229 11.774, 23.175 -0.79
BXD53 m 52.36 15.619   5 6.9851 0.2983 34.196, 71.14 0.13
BXD55 m 28.414 21.023   5 9.4016 0.7399 11.98, 63.92 -0.51
BXD6 m 97.32 67.98   5 30.4 0.6985 20.402, 192.5 1.33
BXD62 m 49.829 35.471   4 17.735 0.7119 16.944, 97.75 0.06
BXD63 m 19.277 4.7246   5 2.1129 0.2451 13.53, 24.58 -0.75
BXD64 m 59.41 40.186   5 17.972 0.6764 28.268, 127.9 0.32
BXD66 m 74.88 48.307   3 27.89 0.6451 43.388, 130.5 0.73
BXD67 m 46.64 16.941   5 7.576 0.3632 30.106, 67.38 -0.02
BXD69 m 16.694 9.9423   4 4.9712 0.5956 10.832, 31.518 -0.82
BXD73 m 48.548 28.722   3 16.582 0.5916 20.388, 77.8 0.03
BXD75 m 18.133 13.726   4 6.8632 0.757 6.58, 38.018 -0.78
BXD77 m 51.29 13.228   5 5.9156 0.2579 32.688, 63.41 0.1
BXD79 m 26.695 19.115   5 8.5485 0.716 6.444, 51.78 -0.55
BXD8 m 16.06 6.1547   2   4.352 0.3832 11.708, 20.412 -0.84
BXD81 m 45.958 3.1201   5 1.3953 0.0679 42.792, 51.1 -0.04
BXD84 m 84.53 107.8   5 48.19 1.2747 10.696, 268.6 0.99
BXD87 m 26.341 15.005   4 7.5023 0.5696 14.052, 46.356 -0.56
BXD89 m 54.55 29.743   5 13.301 0.5453 28.628, 88.87 0.19
BXD90 m 25.886 10.015   4 5.0077 0.3869 14.532, 36.3 -0.58
C57BL/6J m 22.755 5.161   3 2.9797 0.2268 19.622, 28.712 -0.66
DBA/2J m 5.6401 2.0887   3 1.2059 0.3703 3.504, 7.678 -1.12


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 25.332 23.5906192297 72.0358530861 -21.3718530861
BXD100 m 12.7895555556 17.5834094097 47.6005523261 -22.021441215
BXD11 m 164.9166666667 30.4553584678 225.2110817354 104.6222515979
BXD12 m 135.527 26.3751141145 187.7434951558 83.3105048442
BXD27 m 18.6036 23.5906192297 65.3074530861 -28.1002530861
BXD32 m 15.91 26.3751141145 68.1264951558 -36.3064951558
BXD34 m 44.137 26.3751141145 96.3534951558 -8.0794951558
BXD39 m 25.0913333333 30.4553584678 85.3857484021 -35.2030817354
BXD40 m 136.76 26.3751141145 188.9764951558 84.5435048442
BXD43 m 29.0068 23.5906192297 75.7106530861 -17.6970530861
BXD45 m 73.21 23.5906192297 119.9138530861 26.5061469139
BXD48 m 27.9876 23.5906192297 74.6914530861 -18.7162530861
BXD48a m 35.4335 26.3751141145 87.6499951558 -16.7829951558
BXD49 m 76.9164 23.5906192297 123.6202530861 30.2125469139
BXD51 m 17.6923333333 30.4553584678 77.9867484021 -42.6020817354
BXD53 m 52.3604 23.5906192297 99.0642530861 5.6565469139
BXD55 m 28.4144 23.5906192297 75.1182530861 -18.2894530861
BXD6 m 97.3224 23.5906192297 144.0262530861 50.6185469139
BXD62 m 49.829 26.3751141145 102.0454951558 -2.3874951558
BXD63 m 19.2768 23.5906192297 65.9806530861 -27.4270530861
BXD64 m 59.4076 23.5906192297 106.1114530861 12.7037469139
BXD66 m 74.8826666667 30.4553584678 135.1770817354 14.5882515979
BXD67 m 46.64 23.5906192297 93.3438530861 -0.0638530861
BXD69 m 16.694 26.3751141145 68.9104951558 -35.5224951558
BXD73 m 48.548 30.4553584678 108.8424150687 -11.7464150687
BXD75 m 18.1325 26.3751141145 70.3489951558 -34.0839951558
BXD77 m 51.294 23.5906192297 97.9978530861 4.5901469139
BXD79 m 26.6952 23.5906192297 73.3990530861 -20.0086530861
BXD8 m 16.06 37.3000440899 89.905275629 -57.785275629
BXD81 m 45.9584 23.5906192297 92.6622530861 -0.7454530861
BXD84 m 84.5312 23.5906192297 131.2350530861 37.8273469139
BXD87 m 26.3405 26.3751141145 78.5569951558 -25.8759951558
BXD89 m 54.5456 23.5906192297 101.2494530861 7.8417469139
BXD90 m 25.886 26.3751141145 78.1024951558 -26.3304951558
C57BL/6J m 22.7553333333 30.4553584678 83.0497484021 -37.5390817354
DBA/2J m 5.6400666667 30.4553584678 65.9344817354 -54.6543484021




  GWAS USING LINEAR MIXED MODELS