Project measure / variable:   Schoonjans1   TbMCA_plasma_t30_CD

ID, description, units MPD:112702   TbMCA_plasma_t30_CD   plasma bile acid tauro-β-muricholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid tauro-β-muricholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means107.8   ng/mL
Median of the strain means83.13   ng/mL
SD of the strain means± 84.46
Coefficient of variation (CV)0.7839
Min–max range of strain means20.594   –   405.5   ng/mL
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 1194487.4487 34128.2128 5.2928 < 0.0001
Residuals 130 838238.5569 6447.9889


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 26.4 4.0493   5 1.8109 0.1534 19.6, 29.498 -0.96
BXD100 m 117.3 42.074   5 18.816 0.3586 89.99, 191.9 0.11
BXD11 m 57.07 52.01   4 26.006 0.9114 18.554, 130.0 -0.6
BXD12 m 114.1 31.711   3 18.309 0.278 95.63, 150.7 0.08
BXD27 m 247.8 152.2   4 76.09 0.6142 82.22, 434.4 1.66
BXD32 m 81.4 30.463   5 13.624 0.3742 30.918, 113.8 -0.31
BXD34 m 67.79 41.057   5 18.361 0.6056 27.584, 125.4 -0.47
BXD39 m 145.8 64.69   3 37.348 0.4436 76.83, 205.1 0.45
BXD40 m 133.9 58.47   4 29.235 0.4368 74.02, 203.6 0.31
BXD43 m 71.18 51.35   7 19.408 0.7214 17.946, 142.4 -0.43
BXD45 m 174.2 108.7   4 54.34 0.624 108.2, 336.7 0.79
BXD48 m 40.754 20.414   5 9.1296 0.5009 20.24, 69.89 -0.79
BXD48a m 22.445 14.06   4 7.0302 0.6264 9.924, 42.198 -1.01
BXD49 m 84.46 24.065   5 10.762 0.2849 64.48, 120.5 -0.28
BXD51 m 317.2 192.3   5 86.01 0.6064 61.19, 531.9 2.48
BXD53 m 102.1 129.3   4 64.64 1.2668 33.068, 295.9 -0.07
BXD55 m 60.15 19.551   5 8.7433 0.325 43.93, 85.3 -0.56
BXD6 m 139.4 105.9   5 47.38 0.7597 33.782, 255.4 0.37
BXD62 m 405.5 184.0   5 82.28 0.4537 175.9, 624.4 3.53
BXD63 m 66.49 60.41   4 30.204 0.9086 22.976, 152.6 -0.49
BXD64 m 81.81 71.65   5 32.044 0.8758 29.836, 202.4 -0.31
BXD66 m 109.3 9.5307   5 4.2622 0.0872 99.59, 121.8 0.02
BXD67 m 62.85 39.614   4 19.807 0.6303 33.07, 117.4 -0.53
BXD69 m 46.359 11.076   5 4.9533 0.2389 36.802, 60.35 -0.73
BXD73 m 59.15 47.384   4 23.692 0.8011 0.832, 108.9 -0.58
BXD75 m 104.5 54.8   5 24.506 0.5246 42.588, 163.9 -0.04
BXD77 m 48.689 14.747   5 6.595 0.3029 25.976, 62.94 -0.7
BXD79 m 195.2 200.1   5 89.49 1.0253 43.614, 535.3 1.04
BXD8 m 243.2 102.3   5 45.761 0.4208 79.57, 327.2 1.6
BXD81 m 42.862 15.438   3 8.9129 0.3602 31.809, 60.5 -0.77
BXD84 m 91.53 37.289   5 16.676 0.4074 62.43, 155.8 -0.19
BXD87 m 85.8 44.75   5 20.013 0.5215 58.68, 164.7 -0.26
BXD89 m 37.369 20.571   5 9.1997 0.5505 17.54, 70.18 -0.83
BXD90 m 20.594 10.525   5 4.7068 0.511 11.908, 38.014 -1.03
C57BL/6J m 132.4 49.242   5 22.022 0.3719 69.73, 206.1 0.29
DBA/2J m 41.993 26.155   4 13.077 0.6228 13.264, 74.29 -0.78


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 26.4004 35.9109701874 97.4459597593 -44.6451597593
BXD100 m 117.338 35.9109701874 188.3835597593 46.2924402407
BXD11 m 57.067 40.1496852385 136.4983505607 -22.3643505607
BXD12 m 114.0833333333 46.3608631606 205.8027565899 22.3639100768
BXD27 m 247.755 40.1496852385 327.1863505607 168.3236494393
BXD32 m 81.3996 35.9109701874 152.4451597593 10.3540402407
BXD34 m 67.7924 35.9109701874 138.8379597593 -3.2531597593
BXD39 m 145.8433333333 46.3608631606 237.5627565899 54.1239100768
BXD40 m 133.86 40.1496852385 213.2913505607 54.4286494393
BXD43 m 71.1762857143 30.3503092453 131.2207428244 11.1318286041
BXD45 m 174.175 40.1496852385 253.6063505607 94.7436494393
BXD48 m 40.754 35.9109701874 111.7995597593 -30.2915597593
BXD48a m 22.445 40.1496852385 101.8763505607 -56.9863505607
BXD49 m 84.456 35.9109701874 155.5015597593 13.4104402407
BXD51 m 317.178 35.9109701874 388.2235597593 246.1324402407
BXD53 m 102.0555 40.1496852385 181.4868505607 22.6241494393
BXD55 m 60.148 35.9109701874 131.1935597593 -10.8975597593
BXD6 m 139.4464 35.9109701874 210.4919597593 68.4008402407
BXD62 m 405.48 35.9109701874 476.5255597593 334.4344402407
BXD63 m 66.486 40.1496852385 145.9173505607 -12.9453505607
BXD64 m 81.8124 35.9109701874 152.8579597593 10.7668402407
BXD66 m 109.298 35.9109701874 180.3435597593 38.2524402407
BXD67 m 62.8465 40.1496852385 142.2778505607 -16.5848505607
BXD69 m 46.3592 35.9109701874 117.4047597593 -24.6863597593
BXD73 m 59.15 40.1496852385 138.5813505607 -20.2813505607
BXD75 m 104.4576 35.9109701874 175.5031597593 33.4120402407
BXD77 m 48.6888 35.9109701874 119.7343597593 -22.3567597593
BXD79 m 195.1728 35.9109701874 266.2183597593 124.1272402407
BXD8 m 243.154 35.9109701874 314.1995597593 172.1084402407
BXD81 m 42.8616666667 46.3608631606 134.5810899232 -48.8577565899
BXD84 m 91.526 35.9109701874 162.5715597593 20.4804402407
BXD87 m 85.802 35.9109701874 156.8475597593 14.7564402407
BXD89 m 37.3692 35.9109701874 108.4147597593 -33.6763597593
BXD90 m 20.5944 35.9109701874 91.6399597593 -50.4511597593
C57BL/6J m 132.406 35.9109701874 203.4515597593 61.3604402407
DBA/2J m 41.993 40.1496852385 121.4243505607 -37.4383505607




  GWAS USING LINEAR MIXED MODELS