Project measure / variable:   Schoonjans1   MCA_plasma_t30_CD

ID, description, units MPD:112698   MCA_plasma_t30_CD   plasma bile acid γ-muricholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   14 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid γ-muricholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested14 strains
Mean of the strain means2.553   ng/mL
Median of the strain means2.4034   ng/mL
SD of the strain means± 1.2024
Coefficient of variation (CV)0.471
Min–max range of strain means1.212   –   4.988   ng/mL
Mean sample size per strain2.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 6 11.7028 1.9505 2.0281 0.1249
Residuals 15 14.4255 0.9617


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD100 m 1.9367 0.65713   3 0.3794 0.3393 1.272, 2.586 -0.51
BXD12 m 4.988 0.0   1   0.0 0.0 4.988, 4.988 2.03
BXD32 m 4.32 0.0   1   0.0 0.0 4.32, 4.32 1.47
BXD34 m 1.434 0.0   1   0.0 0.0 1.434, 1.434 -0.93
BXD40 m 3.3813 1.6745   3 0.96675 0.4952 1.466, 4.568 0.69
BXD48a m 1.278 0.0   1   0.0 0.0 1.278, 1.278 -1.06
BXD49 m 1.212 0.0   1   0.0 0.0 1.212, 1.212 -1.12
BXD53 m 1.558 0.0   1   0.0 0.0 1.558, 1.558 -0.83
BXD55 m 2.87 0.08768   2   0.062 0.0306 2.808, 2.932 0.26
BXD6 m 3.1013 1.5665   3 0.90441 0.5051 1.616, 4.738 0.46
BXD66 m 1.5315 0.23178   4 0.11589 0.1513 1.322, 1.862 -0.85
BXD75 m 1.722 0.30172   4 0.15086 0.1752 1.42, 2.136 -0.69
BXD77 m 3.0847 1.1412   3 0.65885 0.3699 2.018, 4.288 0.44
BXD81 m 3.324 0.0   1   0.0 0.0 3.324, 3.324 0.64


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD100 m 1.9366666667 0.5661861034 3.1434637795 0.7298695538
BXD40 m 3.3813333333 0.5661861034 4.5881304462 2.1745362205
BXD55 m 2.87 0.6934335264 4.3480185748 1.3919814252
BXD6 m 3.1013333333 0.5661861034 4.3081304462 1.8945362205
BXD66 m 1.5315 0.4903315488 2.5766169569 0.4863830431
BXD75 m 1.722 0.4903315488 2.7671169569 0.6768830431
BXD77 m 3.0846666667 0.5661861034 4.2914637795 1.8778695538




  GWAS USING LINEAR MIXED MODELS