Project measure / variable:   Schoonjans1   CA_plasma_t30_CD

ID, description, units MPD:112690   CA_plasma_t30_CD   plasma bile acid cholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid cholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means48.744   ng/mL
Median of the strain means14.013   ng/mL
SD of the strain means± 60.64
Coefficient of variation (CV)1.2439
Min–max range of strain means0.846   –   207.6   ng/mL
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 604640.5191 17275.4434 2.7043 < 0.0001
Residuals 128 817689.4583 6388.1989


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 90.9 200.1   5 89.5 2.2016 0.902, 448.9 0.7
BXD100 m 13.908 15.7   5 7.0214 1.1289 3.254, 41.646 -0.57
BXD11 m 1.8345 0.70783   4 0.35392 0.3858 0.956, 2.678 -0.77
BXD12 m 48.975 54.93   3 31.715 1.1216 12.03, 112.1 0.0
BXD27 m 27.613 42.917   4 21.459 1.5542 1.6, 91.8 -0.35
BXD32 m 207.6 214.9   5 96.08 1.0352 28.842, 529.7 2.62
BXD34 m 67.03 41.518   5 18.567 0.6194 23.936, 123.2 0.3
BXD39 m 25.606 39.143   3 22.599 1.5287 0.278, 70.69 -0.38
BXD40 m 164.5 110.5   4 55.27 0.6719 33.304, 265.8 1.91
BXD43 m 4.1629 4.9202   7 1.8597 1.1819 0.01, 14.556 -0.74
BXD45 m 23.862 35.773   4 17.887 1.4992 2.422, 77.32 -0.41
BXD48 m 8.1584 1.9364   5 0.86598 0.2374 5.404, 10.072 -0.67
BXD48a m 14.118 4.7196   4 2.3598 0.3343 8.968, 19.22 -0.57
BXD49 m 101.2 72.28   5 32.325 0.714 5.8, 186.9 0.87
BXD51 m 5.4712 3.1331   5 1.4012 0.5727 1.642, 8.766 -0.71
BXD53 m 4.4235 6.2454   4 3.1227 1.4119 0.14, 13.702 -0.73
BXD55 m 144.2 97.27   5 43.502 0.6748 30.484, 275.7 1.57
BXD6 m 191.8 170.0   5 76.01 0.8863 60.52, 405.4 2.36
BXD62 m 7.3432 2.6751   5 1.1964 0.3643 4.074, 10.938 -0.68
BXD63 m 19.909 19.165   4 9.5827 0.9626 3.498, 45.28 -0.48
BXD64 m 1.4785 0.87888   4 0.43944 0.5944 0.534, 2.464 -0.78
BXD66 m 2.8932 2.2249   5 0.99499 0.769 0.432, 5.248 -0.76
BXD67 m 0.846 0.5904   4 0.2952 0.6979 0.068, 1.472 -0.79
BXD69 m 9.726 6.9137   5 3.0919 0.7108 2.334, 18.86 -0.64
BXD73 m 128.5 205.8   3 118.8 1.6017 3.908, 366.1 1.32
BXD75 m 13.198 17.006   5 7.6053 1.2885 3.794, 43.302 -0.59
BXD77 m 86.86 75.69   5 33.849 0.8714 31.01, 216.7 0.63
BXD79 m 9.4764 15.176   5 6.787 1.6015 1.842, 36.608 -0.65
BXD8 m 4.2316 5.8167   5 2.6013 1.3746 0.162, 14.012 -0.73
BXD81 m 77.8 111.4   3 64.29 1.4313 7.604, 206.2 0.48
BXD84 m 1.3005 1.4121   5 0.6315 1.0858 0.548, 3.814 -0.78
BXD87 m 130.2 133.3   5 59.63 1.024 58.02, 367.5 1.34
BXD89 m 5.1656 8.2552   5 3.6918 1.5981 0.126, 19.784 -0.72
BXD90 m 3.1044 4.3862   5 1.9616 1.4129 0.872, 10.926 -0.75
C57BL/6J m 103.0 83.11   5 37.167 0.8069 27.204, 214.1 0.89
DBA/2J m 4.403 3.2107   4 1.6053 0.7292 2.156, 9.084 -0.73


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 90.9016 35.7440873245 161.627383643 20.175816357
BXD100 m 13.9076 35.7440873245 84.633383643 -56.818183643
BXD11 m 1.8345 39.9631045256 80.9083299938 -77.2393299938
BXD12 m 48.9746666667 46.145418311 140.2812607322 -42.3319273989
BXD27 m 27.6135 39.9631045256 106.6873299938 -51.4603299938
BXD32 m 207.5544 35.7440873245 278.280183643 136.828616357
BXD34 m 67.028 35.7440873245 137.753783643 -3.697783643
BXD39 m 25.606 46.145418311 116.9125940656 -65.7005940656
BXD40 m 164.526 39.9631045256 243.5998299938 85.4521700062
BXD43 m 4.1628571429 30.2092674837 63.9370541077 -55.611339822
BXD45 m 23.862 39.9631045256 102.9358299938 -55.2118299938
BXD48 m 8.1584 35.7440873245 78.884183643 -62.567383643
BXD48a m 14.1185 39.9631045256 93.1923299938 -64.9553299938
BXD49 m 101.238 35.7440873245 171.963783643 30.512216357
BXD51 m 5.4712 35.7440873245 76.196983643 -65.254583643
BXD53 m 4.4235 39.9631045256 83.4973299938 -74.6503299938
BXD55 m 144.1588 35.7440873245 214.884583643 73.433016357
BXD6 m 191.766 35.7440873245 262.491783643 121.040216357
BXD62 m 7.3432 35.7440873245 78.068983643 -63.382583643
BXD63 m 19.909 39.9631045256 98.9828299938 -59.1648299938
BXD64 m 1.4785 39.9631045256 80.5523299938 -77.5953299938
BXD66 m 2.8932 35.7440873245 73.618983643 -67.832583643
BXD67 m 0.846 39.9631045256 79.9198299938 -78.2278299938
BXD69 m 9.726 35.7440873245 80.451783643 -60.999783643
BXD73 m 128.5126666667 46.145418311 219.8192607322 37.2060726011
BXD75 m 13.1984 35.7440873245 83.924183643 -57.527383643
BXD77 m 86.8552 35.7440873245 157.580983643 16.129416357
BXD79 m 9.4764 35.7440873245 80.202183643 -61.249383643
BXD8 m 4.2316 35.7440873245 74.957383643 -66.494183643
BXD81 m 77.8033333333 46.145418311 169.1099273989 -13.5032607322
BXD84 m 1.300542 35.7440873245 72.026325643 -69.425241643
BXD87 m 130.222 35.7440873245 200.947783643 59.496216357
BXD89 m 5.1656 35.7440873245 75.891383643 -65.560183643
BXD90 m 3.1044 35.7440873245 73.830183643 -67.621383643
C57BL/6J m 102.9928 35.7440873245 173.718583643 32.267016357
DBA/2J m 4.403 39.9631045256 83.4768299938 -74.6708299938




  GWAS USING LINEAR MIXED MODELS