Project measure / variable:   Schoonjans1   aMCA_plasma_t30_CD

ID, description, units MPD:112686   aMCA_plasma_t30_CD   plasma bile acid α-muricholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   35 strains     sex: m     age: 20wks
Procedure biomarker quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid α-muricholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested35 strains
Mean of the strain means8.2315   ng/mL
Median of the strain means4.502   ng/mL
SD of the strain means± 8.4902
Coefficient of variation (CV)1.0314
Min–max range of strain means1.6307   –   34.18   ng/mL
Mean sample size per strain3.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 30 8488.8425 282.9614 2.0379 0.0054
Residuals 89 12357.5704 138.8491


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 25.591 0.0   1   0.0 0.0 25.591, 25.591 2.04
BXD100 m 3.431 2.283   4 1.1415 0.6654 1.924, 6.818 -0.57
BXD11 m 3.5695 2.105   4 1.0525 0.5897 1.622, 6.178 -0.55
BXD12 m 12.222 13.8   3 7.9671 1.1291 1.77, 27.864 0.47
BXD27 m 4.982 3.5696   4 1.7848 0.7165 2.062, 9.982 -0.38
BXD32 m 24.759 30.636   4 15.318 1.2374 3.078, 68.47 1.95
BXD34 m 7.816 4.8587   5 2.1729 0.6216 2.618, 13.182 -0.05
BXD39 m 1.91 0.0   1   0.0 0.0 1.91, 1.91 -0.74
BXD40 m 34.18 27.628   4 13.814 0.8083 5.606, 64.99 3.06
BXD43 m 2.684 0.0   1   0.0 0.0 2.684, 2.684 -0.65
BXD45 m 6.33 5.0219   4 2.5109 0.7933 1.164, 13.176 -0.22
BXD48 m 3.0976 0.57132   5 0.2555 0.1844 2.472, 3.906 -0.6
BXD48a m 1.8573 0.08566   3 0.04945 0.0461 1.802, 1.956 -0.75
BXD49 m 6.6545 1.8522   4 0.92611 0.2783 4.57, 9.08 -0.19
BXD51 m 1.6307 0.60588   3 0.3498 0.3716 1.264, 2.33 -0.78
BXD53 m 3.417 2.1765   2   1.539 0.637 1.878, 4.956 -0.57
BXD55 m 27.097 23.986   5 10.727 0.8852 3.336, 53.45 2.22
BXD6 m 16.058 12.428   5 5.5581 0.7739 4.19, 31.568 0.92
BXD62 m 6.7288 3.0316   5 1.3558 0.4505 3.076, 10.608 -0.18
BXD63 m 2.799 0.52184   2   0.369 0.1864 2.43, 3.168 -0.64
BXD64 m 1.9435 0.51994   4 0.25997 0.2675 1.354, 2.586 -0.74
BXD66 m 1.885 0.75346   4 0.37673 0.3997 1.298, 2.886 -0.75
BXD67 m 2.0913 0.92867   3 0.53617 0.4441 1.268, 3.098 -0.72
BXD69 m 2.6924 1.8966   5 0.84821 0.7044 1.092, 5.948 -0.65
BXD73 m 11.581 17.464   3 10.083 1.5079 1.058, 31.74 0.39
BXD75 m 7.2424 3.0492   5 1.3636 0.421 5.044, 11.898 -0.12
BXD77 m 20.799 22.435   5 10.033 1.0787 6.73, 59.92 1.48
BXD79 m 3.8647 1.7008   3 0.98194 0.4401 2.712, 5.818 -0.51
BXD8 m 1.95 0.95647   3 0.55222 0.4905 1.284, 3.046 -0.74
BXD81 m 7.7565 8.3141   3 4.8002 1.0719 2.286, 17.324 -0.06
BXD84 m 2.6671 0.31268   2   0.2211 0.1172 2.446, 2.8882 -0.66
BXD87 m 7.3996 9.545   5 4.2687 1.2899 1.626, 24.306 -0.1
BXD89 m 4.502 0.0   1   0.0 0.0 4.502, 4.502 -0.44
C57BL/6J m 12.367 10.793   5 4.8266 0.8727 3.378, 29.878 0.49
DBA/2J m 2.546 1.3267   4 0.66336 0.5211 1.308, 4.384 -0.67


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD100 m 3.431 5.8917125145 15.1377072699 -8.2757072699
BXD11 m 3.5695 5.8917125145 15.2762072699 -8.1372072699
BXD12 m 12.222 6.8031636125 25.7397411872 -1.2957411872
BXD27 m 4.982 5.8917125145 16.6887072699 -6.7247072699
BXD32 m 24.759 5.8917125145 36.4657072699 13.0522927301
BXD34 m 7.816 5.2697078745 18.2867972993 -2.6547972993
BXD40 m 34.1795 5.8917125145 45.8862072699 22.4727927301
BXD45 m 6.33 5.8917125145 18.0367072699 -5.3767072699
BXD48 m 3.0976 5.2697078745 13.5683972993 -7.3731972993
BXD48a m 1.8573333333 6.8031636125 15.3750745206 -11.6604078539
BXD49 m 6.6545 5.8917125145 18.3612072699 -5.0522072699
BXD51 m 1.6306666667 6.8031636125 15.1484078539 -11.8870745206
BXD53 m 3.417 8.3321397436 19.9727841919 -13.1387841919
BXD55 m 27.0968 5.2697078745 37.5675972993 16.6260027007
BXD6 m 16.0584 5.2697078745 26.5291972993 5.5876027007
BXD62 m 6.7288 5.2697078745 17.1995972993 -3.7419972993
BXD63 m 2.799 8.3321397436 19.3547841919 -13.7567841919
BXD64 m 1.9435 5.8917125145 13.6502072699 -9.7632072699
BXD66 m 1.885 5.8917125145 13.5917072699 -9.8217072699
BXD67 m 2.0913333333 6.8031636125 15.6090745206 -11.4264078539
BXD69 m 2.6924 5.2697078745 13.1631972993 -7.7783972993
BXD73 m 11.5813333333 6.8031636125 25.0990745206 -1.9364078539
BXD75 m 7.2424 5.2697078745 17.7131972993 -3.2283972993
BXD77 m 20.7988 5.2697078745 31.2695972993 10.3280027007
BXD79 m 3.8646666667 6.8031636125 17.3824078539 -9.6530745206
BXD8 m 1.95 6.8031636125 15.4677411872 -11.5677411872
BXD81 m 7.7564666667 6.8031636125 21.2742078539 -5.7612745206
BXD84 m 2.6671 8.3321397436 19.2228841919 -13.8886841919
BXD87 m 7.3996 5.2697078745 17.8703972993 -3.0711972993
C57BL/6J m 12.3668 5.2697078745 22.8375972993 1.8960027007
DBA/2J m 2.546 5.8917125145 14.2527072699 -9.1607072699




  GWAS USING LINEAR MIXED MODELS