Project measure / variable:   Schoonjans1   MCA_plasma_t0_CD

ID, description, units MPD:112662   MCA_plasma_t0_CD   plasma bile acid γ-muricholic acid, glucose kinetic test, at 20 wks of age, at 0 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   15 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid γ-muricholic acid, glucose kinetic test, at 20 wks of age, at 0 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested15 strains
Mean of the strain means2.1603   ng/mL
Median of the strain means1.858   ng/mL
SD of the strain means± 0.95879
Coefficient of variation (CV)0.4438
Min–max range of strain means1.326   –   4.824   ng/mL
Mean sample size per strain1.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 7 7.7752 1.1107 0.9331 0.5137
Residuals 13 15.4753 1.1904


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD11 m 1.364 0.0   1   0.0 0.0 1.364, 1.364 -0.83
BXD12 m 4.824 0.0   1   0.0 0.0 4.824, 4.824 2.78
BXD32 m 1.67 0.0   1   0.0 0.0 1.67, 1.67 -0.51
BXD34 m 2.0387 0.89975   3 0.51947 0.4413 1.47, 3.076 -0.13
BXD40 m 2.8693 1.7779   3 1.0265 0.6196 1.604, 4.902 0.74
BXD48 m 1.494 0.23759   2   0.168 0.159 1.326, 1.662 -0.69
BXD49 m 2.749 1.8484   2   1.307 0.6724 1.442, 4.056 0.61
BXD53 m 1.546 0.0   1   0.0 0.0 1.546, 1.546 -0.64
BXD55 m 1.72 0.0   1   0.0 0.0 1.72, 1.72 -0.46
BXD6 m 3.42 1.1455   2   0.81 0.3349 2.61, 4.23 1.31
BXD64 m 1.38 0.0   1   0.0 0.0 1.38, 1.38 -0.81
BXD66 m 1.326 0.10465   2   0.074 0.0789 1.252, 1.4 -0.87
BXD75 m 1.9672 0.81994   5 0.36669 0.4168 1.248, 2.9115 -0.2
BXD77 m 2.179 0.22203   2   0.157 0.1019 2.022, 2.336 0.02
BXD87 m 1.858 0.0   1   0.0 0.0 1.858, 1.858 -0.32


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD34 m 2.0386666667 0.6299231973 3.3995329981 0.6778003352
BXD40 m 2.8693333333 0.6299231973 4.2301996648 1.5084670019
BXD48 m 1.494 0.7714952053 3.1607140601 -0.1727140601
BXD49 m 2.749 0.7714952053 4.4157140601 1.0822859399
BXD6 m 3.42 0.7714952053 5.0867140601 1.7532859399
BXD66 m 1.326 0.7714952053 2.9927140601 -0.3407140601
BXD75 m 1.96716 0.4879364105 3.0212825276 0.9130374724
BXD77 m 2.179 0.7714952053 3.8457140601 0.5122859399




  GWAS USING LINEAR MIXED MODELS