Project measure / variable:   Noll1   Total_IgG_d45

ID, description, units MPD:112631   Total_IgG_d45   total immunoglobulin G (serum IgG) area under curve (AUC) post-infection   [AUC]  day 45  
influenza A (H1N1) virus study
Data set, strains Noll1   CC RIX   34 strains     sex: f     age: 8-12 wks
Procedure immunoglobulin quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Noll1 - total immunoglobulin G (serum IgG) area under curve (AUC) post-infection day 45



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested34 strains
Mean of the strain means9.3445   AUC
Median of the strain means9.3848   AUC
SD of the strain means± 1.4584
Coefficient of variation (CV)0.1561
Min–max range of strain means4.1652   –   11.395   AUC
Mean sample size per strain3.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 27 198.4367 7.3495 17.9221 < 0.0001
Residuals 72 29.5258 0.4101


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
RIX:CC(002 x 021) f 6.9423 0.0   1   0.0 0.0 6.9423, 6.9423 -1.65
RIX:CC(003 x 051) f 11.066 0.27367   3 0.158 0.0247 10.862, 11.377 1.18
RIX:CC(003 x 062) f 11.395 0.12939   8 0.04574 0.0114 11.215, 11.578 1.41
RIX:CC(007 x 075) f 8.0994 0.0   1   0.0 0.0 8.0994, 8.0994 -0.85
RIX:CC(013 x 026) f 8.8505 0.0   1   0.0 0.0 8.8505, 8.8505 -0.34
RIX:CC(013 x 041) f 7.5527 1.3185   6 0.53827 0.1746 5.0454, 8.8667 -1.23
RIX:CC(015 x 018) f 10.368 0.50063   2   0.354 0.0483 10.014, 10.722 0.7
RIX:CC(015 x 059) f 9.2839 0.0   1   0.0 0.0 9.2839, 9.2839 -0.04
RIX:CC(016 x 038) f 11.089 0.49927   6 0.20383 0.045 10.08, 11.382 1.2
RIX:CC(017 x 041) f 9.5088 0.21898   3 0.12643 0.023 9.2586, 9.6657 0.11
RIX:CC(018 x 009) f 11.179 0.36058   6 0.14721 0.0323 10.562, 11.497 1.26
RIX:CC(018 x 065) f 9.2413 0.82405   3 0.47576 0.0892 8.7158, 10.191 -0.07
RIX:CC(019 x 002) f 11.135 0.40204   4 0.20102 0.0361 10.586, 11.507 1.23
RIX:CC(025 x 028) f 9.4633 0.93506   3 0.53986 0.0988 8.6837, 10.5 0.08
RIX:CC(026 x 034) f 9.0395 0.32257   4 0.16128 0.0357 8.7611, 9.4632 -0.21
RIX:CC(028 x 030) f 10.481 0.89952   5 0.40228 0.0858 9.5269, 11.594 0.78
RIX:CC(032 x 017) f 8.8749 0.29221   3 0.16871 0.0329 8.5553, 9.1284 -0.32
RIX:CC(034 x 016) f 9.3062 0.42648   4 0.21324 0.0458 8.6916, 9.6655 -0.03
RIX:CC(035 x 020) f 9.5445 0.05042   2   0.03565 0.0053 9.5088, 9.5801 0.14
RIX:CC(035 x 071) f 4.1652 1.418   2   1.0027 0.3404 3.1625, 5.1679 -3.55
RIX:CC(037 x 057) f 8.2262 0.0   1   0.0 0.0 8.2262, 8.2262 -0.77
RIX:CC(038 x 013) f 10.263 0.03536   2   0.025 0.0034 10.238, 10.288 0.63
RIX:CC(041 x 016) f 8.6702 0.30643   4 0.15322 0.0353 8.3891, 9.0917 -0.46
RIX:CC(042 x 017) f 10.986 0.86511   5 0.38689 0.0787 9.9098, 11.969 1.13
RIX:CC(042 x 019) f 8.3607 0.71045   3 0.41018 0.085 7.5694, 8.9438 -0.67
RIX:CC(043 x 037) f 10.16 0.17253   2   0.122 0.017 10.038, 10.282 0.56
RIX:CC(051 x 005) f 8.4986 0.62127   3 0.35869 0.0731 7.8146, 9.0279 -0.58
RIX:CC(051 x 009) f 8.9923 0.8597   3 0.49635 0.0956 8.0574, 9.7488 -0.24
RIX:CC(057 x 052) f 10.631 0.60251   4 0.30125 0.0567 9.768, 11.113 0.88
RIX:CC(062 x 046) f 8.2142 0.66411   2   0.4696 0.0808 7.7446, 8.6838 -0.78
RIX:CC(063 x 002) f 9.7886 0.22233   3 0.12836 0.0227 9.6383, 10.044 0.3
RIX:CC(074 x 062) f 10.273 0.0   1   0.0 0.0 10.273, 10.273 0.64
RIX:CC(075 x 021) f 9.7913 0.3404   2   0.2407 0.0348 9.5506, 10.032 0.31
RIX:CC(075 x 035) f 8.2719 0.26724   3 0.15429 0.0323 7.9691, 8.4749 -0.74


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
RIX:CC(003 x 051) f 11.066 0.369720866 11.8030250762 10.3289749238
RIX:CC(003 x 062) f 11.39475 0.2264068673 11.8460838411 10.9434161589
RIX:CC(013 x 041) f 7.5526833333 0.2614321315 8.0738387627 7.031527904
RIX:CC(015 x 018) f 10.368 0.4528137345 11.2706676822 9.4653323178
RIX:CC(016 x 038) f 11.089 0.2614321315 11.6101554293 10.5678445707
RIX:CC(017 x 041) f 9.5087666667 0.369720866 10.2457917429 8.7717415904
RIX:CC(018 x 009) f 11.1791666667 0.2614321315 11.700322096 10.6580112373
RIX:CC(018 x 065) f 9.2412666667 0.369720866 9.9782917429 8.5042415904
RIX:CC(019 x 002) f 11.13525 0.3201876623 11.7735324393 10.4969675607
RIX:CC(025 x 028) f 9.4632666667 0.369720866 10.2002917429 8.7262415904
RIX:CC(026 x 034) f 9.039525 0.3201876623 9.6778074393 8.4012425607
RIX:CC(028 x 030) f 10.4809 0.2863845514 11.0517971692 9.9100028308
RIX:CC(032 x 017) f 8.8749 0.369720866 9.6119250762 8.1378749238
RIX:CC(034 x 016) f 9.306175 0.3201876623 9.9444574393 8.6678925607
RIX:CC(035 x 020) f 9.54445 0.4528137345 10.4471176822 8.6417823178
RIX:CC(035 x 071) f 4.1652 0.4528137345 5.0678676822 3.2625323178
RIX:CC(038 x 013) f 10.263 0.4528137345 11.1656676822 9.3603323178
RIX:CC(041 x 016) f 8.670175 0.3201876623 9.3084574393 8.0318925607
RIX:CC(042 x 017) f 10.98576 0.2863845514 11.5566571692 10.4148628308
RIX:CC(042 x 019) f 8.3606666667 0.369720866 9.0976917429 7.6236415904
RIX:CC(043 x 037) f 10.16 0.4528137345 11.0626676822 9.2573323178
RIX:CC(051 x 005) f 8.4986 0.369720866 9.2356250762 7.7615749238
RIX:CC(051 x 009) f 8.9923 0.369720866 9.7293250762 8.2552749238
RIX:CC(057 x 052) f 10.63075 0.3201876623 11.2690324393 9.9924675607
RIX:CC(062 x 046) f 8.2142 0.4528137345 9.1168676822 7.3115323178
RIX:CC(063 x 002) f 9.7886 0.369720866 10.5256250762 9.0515749238
RIX:CC(075 x 021) f 9.7913 0.4528137345 10.6939676822 8.8886323178
RIX:CC(075 x 035) f 8.2718666667 0.369720866 9.0088917429 7.5348415904




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA