Project measure / variable:   Noll1   Total_IgG_d15

ID, description, units MPD:112629   Total_IgG_d15   total immunoglobulin G (serum IgG) area under curve (AUC) post-infection   [AUC]  day 15  
influenza A (H1N1) virus study
Data set, strains Noll1   CC RIX   32 strains     sex: f     age: 8-12 wks
Procedure immunoglobulin quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Noll1 - total immunoglobulin G (serum IgG) area under curve (AUC) post-infection day 15



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested32 strains
Mean of the strain means6.6872   AUC
Median of the strain means6.7655   AUC
SD of the strain means± 1.5334
Coefficient of variation (CV)0.2293
Min–max range of strain means3.2526   –   10.281   AUC
Mean sample size per strain3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 28 216.6386 7.7371 5.5945 < 0.0001
Residuals 63 87.1286 1.383


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
RIX:CC(002 x 021) f 5.6883 1.2594   4 0.62971 0.2214 4.4963, 7.2687 -0.65
RIX:CC(003 x 051) f 3.2526 0.0   1   0.0 0.0 3.2526, 3.2526 -2.24
RIX:CC(003 x 062) f 4.4892 0.67699   4 0.3385 0.1508 3.7357, 5.1024 -1.43
RIX:CC(013 x 041) f 3.415 1.7303   6 0.70641 0.5067 1.6223, 5.5897 -2.13
RIX:CC(015 x 018) f 9.2422 0.10713   2   0.07575 0.0116 9.1665, 9.318 1.67
RIX:CC(016 x 038) f 7.3306 0.23378   3 0.13497 0.0319 7.0769, 7.5373 0.42
RIX:CC(017 x 041) f 5.2168 0.30929   2   0.2187 0.0593 4.9981, 5.4355 -0.96
RIX:CC(018 x 009) f 10.281 0.21306   3 0.12301 0.0207 10.035, 10.407 2.34
RIX:CC(018 x 065) f 6.2732 0.36219   4 0.1811 0.0577 5.9576, 6.672 -0.27
RIX:CC(019 x 002) f 6.6953 2.379   2   1.6822 0.3553 5.0131, 8.3775 0.01
RIX:CC(025 x 028) f 6.3769 2.8783   4 1.4391 0.4514 2.1875, 8.7134 -0.2
RIX:CC(026 x 034) f 5.5714 0.51532   3 0.29752 0.0925 5.0778, 6.106 -0.73
RIX:CC(028 x 030) f 6.0714 1.4124   4 0.70618 0.2326 4.0091, 7.1745 -0.4
RIX:CC(032 x 013) f 6.7289 1.0299   3 0.59461 0.1531 5.7331, 7.7898 0.03
RIX:CC(032 x 017) f 8.2416 1.2457   3 0.71923 0.1512 7.0586, 9.5418 1.01
RIX:CC(034 x 016) f 7.2467 0.66167   3 0.38201 0.0913 6.6269, 7.9435 0.36
RIX:CC(035 x 071) f 6.0627 0.82195   3 0.47455 0.1356 5.2687, 6.91 -0.41
RIX:CC(037 x 046) f 4.998 0.97905   3 0.56526 0.1959 4.0091, 5.9669 -1.1
RIX:CC(037 x 057) f 5.6947 1.1512   3 0.66465 0.2022 4.4868, 6.7793 -0.65
RIX:CC(038 x 013) f 6.8021 1.153   3 0.66566 0.1695 5.989, 8.1216 0.07
RIX:CC(041 x 016) f 5.5238 1.1472   3 0.66236 0.2077 4.1991, 6.196 -0.76
RIX:CC(042 x 017) f 8.8523 1.0038   4 0.5019 0.1134 7.6457, 9.9129 1.41
RIX:CC(042 x 019) f 7.739 0.48622   4 0.24311 0.0628 7.1673, 8.1915 0.69
RIX:CC(042 x 025) f 6.7071 0.89895   4 0.44947 0.134 6.0812, 8.0417 0.01
RIX:CC(043 x 037) f 8.2403 0.73474   3 0.4242 0.0892 7.4477, 8.8987 1.01
RIX:CC(051 x 009) f 8.1776 0.77891   3 0.4497 0.0952 7.6887, 9.0758 0.97
RIX:CC(052 x 007) f 6.9347 1.4762   2   1.0438 0.2129 5.8909, 7.9785 0.16
RIX:CC(057 x 052) f 7.1985 0.35293   3 0.20376 0.049 6.8274, 7.5299 0.33
RIX:CC(058 x 022) f 7.1067 0.0   1   0.0 0.0 7.1067, 7.1067 0.27
RIX:CC(071 x 058) f 7.3293 0.31275   2   0.22115 0.0427 7.1082, 7.5505 0.42
RIX:CC(075 x 021) f 6.8349 0.0   1   0.0 0.0 6.8349, 6.8349 0.1
RIX:CC(075 x 035) f 7.6682 0.09702   2   0.0686 0.0127 7.5996, 7.7368 0.64


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
RIX:CC(002 x 021) f 5.68825 0.588003848 6.8632819287 4.5132180713
RIX:CC(003 x 062) f 4.489175 0.588003848 5.6642069287 3.3141430713
RIX:CC(013 x 041) f 3.4149833333 0.4801031315 4.3743928856 2.4555737811
RIX:CC(015 x 018) f 9.24225 0.8315630166 10.9039960898 7.5805039102
RIX:CC(016 x 038) f 7.3306333333 0.6789683599 8.687443334 5.9738233327
RIX:CC(017 x 041) f 5.2168 0.8315630166 6.8785460898 3.5550539102
RIX:CC(018 x 009) f 10.281 0.6789683599 11.6378100007 8.9241899993
RIX:CC(018 x 065) f 6.273175 0.588003848 7.4482069287 5.0981430713
RIX:CC(019 x 002) f 6.6953 0.8315630166 8.3570460898 5.0335539102
RIX:CC(025 x 028) f 6.3769 0.588003848 7.5519319287 5.2018680713
RIX:CC(026 x 034) f 5.5714 0.6789683599 6.9282100007 4.2145899993
RIX:CC(028 x 030) f 6.0714 0.588003848 7.2464319287 4.8963680713
RIX:CC(032 x 013) f 6.7288666667 0.6789683599 8.0856766673 5.372056666
RIX:CC(032 x 017) f 8.2416333333 0.6789683599 9.598443334 6.8848233327
RIX:CC(034 x 016) f 7.2467 0.6789683599 8.6035100007 5.8898899993
RIX:CC(035 x 071) f 6.0627 0.6789683599 7.4195100007 4.7058899993
RIX:CC(037 x 046) f 4.998 0.6789683599 6.3548100007 3.6411899993
RIX:CC(037 x 057) f 5.6947 0.6789683599 7.0515100007 4.3378899993
RIX:CC(038 x 013) f 6.8021 0.6789683599 8.1589100007 5.4452899993
RIX:CC(041 x 016) f 5.5237666667 0.6789683599 6.8805766673 4.166956666
RIX:CC(042 x 017) f 8.852275 0.588003848 10.0273069287 7.6772430713
RIX:CC(042 x 019) f 7.739 0.588003848 8.9140319287 6.5639680713
RIX:CC(042 x 025) f 6.707125 0.588003848 7.8821569287 5.5320930713
RIX:CC(043 x 037) f 8.2402666667 0.6789683599 9.5970766673 6.883456666
RIX:CC(051 x 009) f 8.1775666667 0.6789683599 9.5343766673 6.820756666
RIX:CC(052 x 007) f 6.9347 0.8315630166 8.5964460898 5.2729539102
RIX:CC(057 x 052) f 7.1985 0.6789683599 8.5553100007 5.8416899993
RIX:CC(071 x 058) f 7.32935 0.8315630166 8.9910960898 5.6676039102
RIX:CC(075 x 035) f 7.6682 0.8315630166 9.3299460898 6.0064539102




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA