Project measure / variable:   Noll1   Total_IgG_d10

ID, description, units MPD:112628   Total_IgG_d10   total immunoglobulin G (serum IgG) area under curve (AUC) post-infection   [AUC]  day 10  
influenza A (H1N1) virus study
Data set, strains Noll1   CC RIX   38 strains     sex: f     age: 8-12 wks
Procedure immunoglobulin quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Noll1 - total immunoglobulin G (serum IgG) area under curve (AUC) post-infection day 10



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested38 strains
Mean of the strain means4.2177   AUC
Median of the strain means3.9002   AUC
SD of the strain means± 1.5523
Coefficient of variation (CV)0.368
Min–max range of strain means0.34565   –   6.8364   AUC
Mean sample size per strain3.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 287.5121 8.4562 4.7547 < 0.0001
Residuals 95 168.9593 1.7785


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
RIX:CC(003 x 051) f 3.5649 0.98464   3 0.56848 0.2762 2.5668, 4.5355 -0.42
RIX:CC(005 x 020) f 3.7625 1.024   3 0.59121 0.2722 2.7053, 4.7497 -0.29
RIX:CC(007 x 075) f 5.5137 1.356   4 0.67802 0.2459 3.9993, 7.2931 0.83
RIX:CC(013 x 026) f 3.6964 0.61047   5 0.27301 0.1652 2.9743, 4.5373 -0.34
RIX:CC(013 x 041) f 2.1795 1.0845   8 0.38343 0.4976 1.0496, 3.8207 -1.31
RIX:CC(015 x 018) f 5.2353 1.221   3 0.70494 0.2332 4.0656, 6.5018 0.66
RIX:CC(015 x 059) f 3.7611 0.52886   3 0.30534 0.1406 3.1754, 4.2037 -0.29
RIX:CC(016 x 038) f 6.8364 0.54835   3 0.31659 0.0802 6.2174, 7.2614 1.69
RIX:CC(017 x 041) f 3.5926 0.06385   2   0.04515 0.0178 3.5474, 3.6377 -0.4
RIX:CC(018 x 009) f 5.3045 0.87399   3 0.5046 0.1648 4.4689, 6.2124 0.7
RIX:CC(018 x 065) f 5.9257 0.28111   3 0.1623 0.0474 5.7249, 6.247 1.1
RIX:CC(019 x 002) f 4.6311 2.0003   6 0.81661 0.4319 1.6002, 7.3725 0.27
RIX:CC(025 x 028) f 5.0944 0.7124   4 0.3562 0.1398 4.2982, 5.8063 0.56
RIX:CC(026 x 034) f 3.5777 1.3469   4 0.67346 0.3765 2.0414, 5.0827 -0.41
RIX:CC(028 x 030) f 4.2315 1.8763   5 0.8391 0.4434 2.3865, 7.0318 0.01
RIX:CC(032 x 013) f 2.4253 1.988   7 0.75138 0.8197 0.54901, 5.7423 -1.15
RIX:CC(032 x 017) f 5.7387 0.23653   2   0.16725 0.0412 5.5715, 5.906 0.98
RIX:CC(034 x 016) f 6.409 0.58187   3 0.33594 0.0908 5.7375, 6.7652 1.41
RIX:CC(035 x 071) f 3.5264 2.0917   3 1.2076 0.5932 2.0784, 5.9245 -0.45
RIX:CC(037 x 046) f 0.34565 0.30048   3 0.17348 0.8693 0.13169, 0.68917 -2.49
RIX:CC(037 x 057) f 5.6968 0.43076   3 0.2487 0.0756 5.2072, 6.0177 0.95
RIX:CC(038 x 013) f 2.1207 0.64427   3 0.37197 0.3038 1.444, 2.7267 -1.35
RIX:CC(041 x 016) f 3.3395 2.2962   3 1.3257 0.6876 0.69478, 4.825 -0.57
RIX:CC(042 x 017) f 3.5479 0.58004   2   0.41015 0.1635 3.1377, 3.958 -0.43
RIX:CC(042 x 019) f 2.9951 0.52942   3 0.30566 0.1768 2.3855, 3.3396 -0.79
RIX:CC(042 x 025) f 4.9212 0.45015   3 0.25989 0.0915 4.4937, 5.391 0.45
RIX:CC(043 x 037) f 3.0469 1.6101   9 0.53669 0.5284 0.56865, 5.6797 -0.75
RIX:CC(051 x 005) f 3.2175 0.0   1   0.0 0.0 3.2175, 3.2175 -0.64
RIX:CC(051 x 009) f 6.6534 1.5764   2   1.1147 0.2369 5.5388, 7.7681 1.57
RIX:CC(052 x 007) f 6.6068 1.0123   3 0.58448 0.1532 5.6738, 7.6832 1.54
RIX:CC(057 x 052) f 5.2257 1.6515   3 0.95349 0.316 3.3982, 6.6113 0.65
RIX:CC(058 x 022) f 5.5715 0.0   1   0.0 0.0 5.5715, 5.5715 0.87
RIX:CC(062 x 046) f 3.4541 0.66804   3 0.38569 0.1934 2.703, 3.9819 -0.49
RIX:CC(063 x 002) f 1.3234 0.52744   4 0.26372 0.3985 0.81363, 1.9067 -1.86
RIX:CC(074 x 058) f 6.0812 2.7811   2   1.9665 0.4573 4.1146, 8.0477 1.2
RIX:CC(074 x 062) f 2.392 0.0   1   0.0 0.0 2.392, 2.392 -1.18
RIX:CC(075 x 021) f 4.6886 0.99727   8 0.35259 0.2127 3.0224, 5.9517 0.3
RIX:CC(075 x 035) f 4.0378 3.0368   2   2.1474 0.7521 1.8905, 6.1852 -0.12


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
RIX:CC(003 x 051) f 3.5649 0.7699608873 5.0934656242 2.0363343758
RIX:CC(005 x 020) f 3.7625333333 0.7699608873 5.2910989575 2.2339677092
RIX:CC(007 x 075) f 5.51375 0.6668056883 6.8375266619 4.1899733381
RIX:CC(013 x 026) f 3.69636 0.5964091387 4.8803818412 2.5123381588
RIX:CC(013 x 041) f 2.179475 0.4715028239 3.1155264544 1.2434235456
RIX:CC(015 x 018) f 5.2352666667 0.7699608873 6.7638322908 3.7067010425
RIX:CC(015 x 059) f 3.7610666667 0.7699608873 5.2896322908 2.2325010425
RIX:CC(016 x 038) f 6.8363666667 0.7699608873 8.3649322908 5.3078010425
RIX:CC(017 x 041) f 3.59255 0.9430056479 5.4646529088 1.7204470912
RIX:CC(018 x 009) f 5.3045333333 0.7699608873 6.8330989575 3.7759677092
RIX:CC(018 x 065) f 5.9257333333 0.7699608873 7.4542989575 4.3971677092
RIX:CC(019 x 002) f 4.6311333333 0.5444445647 5.7119924517 3.550274215
RIX:CC(025 x 028) f 5.094375 0.6668056883 6.4181516619 3.7705983381
RIX:CC(026 x 034) f 3.577675 0.6668056883 4.9014516619 2.2538983381
RIX:CC(028 x 030) f 4.23146 0.5964091387 5.4154818412 3.0474381588
RIX:CC(032 x 013) f 2.4252957143 0.5040577212 3.4259768111 1.4246146175
RIX:CC(032 x 017) f 5.73875 0.9430056479 7.6108529088 3.8666470912
RIX:CC(034 x 016) f 6.4089666667 0.7699608873 7.9375322908 4.8804010425
RIX:CC(035 x 071) f 3.5263666667 0.7699608873 5.0549322908 1.9978010425
RIX:CC(037 x 046) f 0.3456466667 0.7699608873 1.8742122908 -1.1829189575
RIX:CC(037 x 057) f 5.6967666667 0.7699608873 7.2253322908 4.1682010425
RIX:CC(038 x 013) f 2.1207 0.7699608873 3.6492656242 0.5921343758
RIX:CC(041 x 016) f 3.3394933333 0.7699608873 4.8680589575 1.8109277092
RIX:CC(042 x 017) f 3.54785 0.9430056479 5.4199529088 1.6757470912
RIX:CC(042 x 019) f 2.9951 0.7699608873 4.5236656242 1.4665343758
RIX:CC(042 x 025) f 4.9211666667 0.7699608873 6.4497322908 3.3926010425
RIX:CC(043 x 037) f 3.0469055556 0.4445371255 3.9294233301 2.164387781
RIX:CC(051 x 009) f 6.65345 0.9430056479 8.5255529088 4.7813470912
RIX:CC(052 x 007) f 6.6068 0.7699608873 8.1353656242 5.0782343758
RIX:CC(057 x 052) f 5.2256666667 0.7699608873 6.7542322908 3.6971010425
RIX:CC(062 x 046) f 3.4540666667 0.7699608873 4.9826322908 1.9255010425
RIX:CC(063 x 002) f 1.3234175 0.6668056883 2.6471941619 -0.0003591619
RIX:CC(074 x 058) f 6.08115 0.9430056479 7.9532529088 4.2090470912
RIX:CC(075 x 021) f 4.68855 0.4715028239 5.6246014544 3.7524985456
RIX:CC(075 x 035) f 4.03785 0.9430056479 5.9099529088 2.1657470912




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA