Project measure / variable:   Noll1   IgG3_d10

ID, description, units MPD:112623   IgG3_d10   immunoglobulin G3 (serum IgG3) area under curve (AUC) post-infection   [AUC]  day 10  
influenza A (H1N1) virus study
Data set, strains Noll1   CC RIX   37 strains     sex: f     age: 8-12 wks
Procedure immunoglobulin quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Noll1 - immunoglobulin G3 (serum IgG3) area under curve (AUC) post-infection day 10



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested37 strains
Mean of the strain means1.1817   AUC
Median of the strain means0.84947   AUC
SD of the strain means± 0.99215
Coefficient of variation (CV)0.8396
Min–max range of strain means0.0739   –   3.8225   AUC
Mean sample size per strain3.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 111.5985 3.2823 5.2027 < 0.0001
Residuals 100 63.0886 0.6309


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
RIX:CC(002 x 021) f 2.1282 2.3009   3 1.3284 1.0812 0.00190848, 4.5709 0.95
RIX:CC(003 x 051) f 0.84947 0.74076   3 0.42768 0.872 0.23447, 1.6718 -0.33
RIX:CC(005 x 020) f 0.22305 0.0887   3 0.05121 0.3977 0.16774, 0.32536 -0.97
RIX:CC(007 x 075) f 1.0795 0.97258   4 0.48629 0.901 0.25448, 2.441 -0.1
RIX:CC(013 x 026) f 0.74758 0.34972   5 0.1564 0.4678 0.44414, 1.2355 -0.44
RIX:CC(013 x 041) f 0.19679 0.11555   8 0.04085 0.5872 0.0598, 0.35473 -0.99
RIX:CC(015 x 018) f 3.5089 0.82969   3 0.47902 0.2365 2.7042, 4.3615 2.35
RIX:CC(015 x 059) f 1.4833 0.17778   3 0.10264 0.1199 1.3467, 1.6843 0.3
RIX:CC(016 x 038) f 3.3283 0.94522   3 0.54572 0.284 2.2994, 4.1581 2.16
RIX:CC(017 x 041) f 0.16171 0.0789   2   0.05579 0.4879 0.10592, 0.2175 -1.03
RIX:CC(018 x 009) f 0.96952 0.1696   3 0.09792 0.1749 0.78886, 1.1253 -0.21
RIX:CC(018 x 065) f 0.58113 0.4865   3 0.28088 0.8372 0.22435, 1.1353 -0.61
RIX:CC(019 x 002) f 1.6322 1.0097   6 0.4122 0.6186 0.21455, 3.0367 0.45
RIX:CC(025 x 028) f 1.1119 0.7715   4 0.38575 0.6938 0.22228, 2.0959 -0.07
RIX:CC(026 x 034) f 1.3847 0.47091   4 0.23546 0.3401 0.95063, 2.0544 0.2
RIX:CC(028 x 030) f 0.74347 0.77754   5 0.34772 1.0458 0.23028, 2.1042 -0.44
RIX:CC(032 x 013) f 0.73465 0.55607   7 0.21017 0.7569 0.23572, 1.7113 -0.45
RIX:CC(032 x 017) f 3.6131 0.61178   3 0.35321 0.1693 2.9383, 4.1315 2.45
RIX:CC(034 x 016) f 3.8225 1.124   3 0.64894 0.294 2.5937, 4.7987 2.66
RIX:CC(035 x 071) f 0.65711 0.13213   3 0.07629 0.2011 0.50454, 0.73367 -0.53
RIX:CC(037 x 046) f 0.0739 0.03964   3 0.02289 0.5364 0.04971, 0.11965 -1.12
RIX:CC(037 x 057) f 1.8852 0.58089   3 0.33538 0.3081 1.224, 2.3134 0.71
RIX:CC(038 x 013) f 0.2828 0.24984   3 0.14425 0.8835 0.11596, 0.57004 -0.91
RIX:CC(041 x 016) f 1.2819 1.0463   3 0.60408 0.8162 0.10433, 2.1046 0.1
RIX:CC(042 x 025) f 1.1952 0.63831   3 0.36853 0.534 0.68146, 1.9098 0.01
RIX:CC(043 x 037) f 0.70839 0.72603   9 0.24201 1.0249 0.02633, 2.1446 -0.48
RIX:CC(051 x 005) f 1.0374 1.1543   4 0.57717 1.1128 0.33284, 2.7598 -0.15
RIX:CC(051 x 009) f 1.2928 0.99583   2   0.70416 0.7703 0.58869, 1.997 0.11
RIX:CC(052 x 007) f 0.65887 0.27144   3 0.15671 0.412 0.42939, 0.95849 -0.53
RIX:CC(057 x 052) f 0.64839 0.38652   3 0.22316 0.5961 0.29851, 1.0633 -0.54
RIX:CC(058 x 022) f 0.70341 0.0   1   0.0 0.0 0.70341, 0.70341 -0.48
RIX:CC(062 x 046) f 0.23223 0.139   4 0.0695 0.5986 0.08338, 0.41036 -0.96
RIX:CC(063 x 002) f 0.38594 0.28674   4 0.14337 0.743 0.1667, 0.79249 -0.8
RIX:CC(074 x 058) f 0.76781 0.89049   3 0.51412 1.1598 0.08946, 1.7762 -0.42
RIX:CC(074 x 062) f 0.15384 0.0   1   0.0 0.0 0.15384, 0.15384 -1.04
RIX:CC(075 x 021) f 1.5975 1.1072   8 0.39145 0.6931 0.26703, 3.4117 0.42
RIX:CC(075 x 035) f 1.8605 2.2672   2   1.6032 1.2186 0.25739, 3.4637 0.68


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
RIX:CC(002 x 021) f 2.1281694933 0.4585798285 3.0379788121 1.2183601746
RIX:CC(003 x 051) f 0.84947 0.4585798285 1.7592793188 -0.0603393188
RIX:CC(005 x 020) f 0.2230533333 0.4585798285 1.1328626521 -0.6867559854
RIX:CC(007 x 075) f 1.0794675 0.3971417812 1.8673854827 0.2915495173
RIX:CC(013 x 026) f 0.747578 0.3552144078 1.452313268 0.042842732
RIX:CC(013 x 041) f 0.1967875 0.2808216466 0.7539296486 -0.3603546486
RIX:CC(015 x 018) f 3.5088666667 0.4585798285 4.4186759854 2.5990573479
RIX:CC(015 x 059) f 1.4833 0.4585798285 2.3931093188 0.5734906812
RIX:CC(016 x 038) f 3.3283333333 0.4585798285 4.2381426521 2.4185240146
RIX:CC(017 x 041) f 0.16171 0.5616432931 1.2759942971 -0.9525742971
RIX:CC(018 x 009) f 0.9695233333 0.4585798285 1.8793326521 0.0597140146
RIX:CC(018 x 065) f 0.58113 0.4585798285 1.4909393188 -0.3286793188
RIX:CC(019 x 002) f 1.6321583333 0.3242649065 2.2754906722 0.9888259944
RIX:CC(025 x 028) f 1.1119425 0.3971417812 1.8998604827 0.3240245173
RIX:CC(026 x 034) f 1.3847325 0.3971417812 2.1726504827 0.5968145173
RIX:CC(028 x 030) f 0.74347 0.3552144078 1.448205268 0.038734732
RIX:CC(032 x 013) f 0.7346457143 0.3002109681 1.3302557245 0.1390357041
RIX:CC(032 x 017) f 3.6131 0.4585798285 4.5229093188 2.7032906812
RIX:CC(034 x 016) f 3.8225333333 0.4585798285 4.7323426521 2.9127240146
RIX:CC(035 x 071) f 0.65711 0.4585798285 1.5669193188 -0.2526993188
RIX:CC(037 x 046) f 0.0739033333 0.4585798285 0.9837126521 -0.8359059854
RIX:CC(037 x 057) f 1.8852333333 0.4585798285 2.7950426521 0.9754240146
RIX:CC(038 x 013) f 0.2827966667 0.4585798285 1.1926059854 -0.6270126521
RIX:CC(041 x 016) f 1.28191 0.4585798285 2.1917193188 0.3721006812
RIX:CC(042 x 025) f 1.1952333333 0.4585798285 2.1050426521 0.2854240146
RIX:CC(043 x 037) f 0.7083944444 0.2647611874 1.2336730995 0.1831157893
RIX:CC(051 x 005) f 1.03738 0.3971417812 1.8252979827 0.2494620173
RIX:CC(051 x 009) f 1.292845 0.5616432931 2.4071292971 0.1785607029
RIX:CC(052 x 007) f 0.6588666667 0.4585798285 1.5686759854 -0.2509426521
RIX:CC(057 x 052) f 0.64839 0.4585798285 1.5581993188 -0.2614193188
RIX:CC(062 x 046) f 0.2322275 0.3971417812 1.0201454827 -0.5556904827
RIX:CC(063 x 002) f 0.3859375 0.3971417812 1.1738554827 -0.4019804827
RIX:CC(074 x 058) f 0.76781 0.4585798285 1.6776193188 -0.1419993188
RIX:CC(075 x 021) f 1.59745 0.2808216466 2.1545921486 1.0403078514
RIX:CC(075 x 035) f 1.860545 0.5616432931 2.9748292971 0.7462607029




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA