Project measure / variable:   Noll1   IgG2b_d45

ID, description, units MPD:112621   IgG2b_d45   immunoglobulin G2b (serum IgG2b) area under curve (AUC) post-infection   [AUC]  day 45  
influenza A (H1N1) virus study
Data set, strains Noll1   CC RIX   32 strains     sex: f     age: 8-12 wks
Procedure immunoglobulin quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Noll1 - immunoglobulin G2b (serum IgG2b) area under curve (AUC) post-infection day 45



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested32 strains
Mean of the strain means6.1959   AUC
Median of the strain means5.9146   AUC
SD of the strain means± 2.1447
Coefficient of variation (CV)0.3462
Min–max range of strain means1.363   –   10.263   AUC
Mean sample size per strain3.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 25 473.4492 18.938 9.655 < 0.0001
Residuals 71 139.2641 1.9615


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
RIX:CC(002 x 021) f 3.8465 2.7807   3 1.6054 0.7229 1.5591, 6.9416 -1.1
RIX:CC(003 x 051) f 8.9197 0.53385   3 0.30822 0.0599 8.3194, 9.3412 1.27
RIX:CC(003 x 062) f 10.263 0.40614   8 0.14359 0.0396 9.4165, 10.838 1.9
RIX:CC(007 x 075) f 4.8764 0.0   1   0.0 0.0 4.8764, 4.8764 -0.62
RIX:CC(013 x 026) f 6.8475 0.0   1   0.0 0.0 6.8475, 6.8475 0.3
RIX:CC(013 x 041) f 5.0386 1.8984   6 0.77503 0.3768 2.5057, 7.0987 -0.54
RIX:CC(015 x 018) f 6.9626 1.7665   2   1.2491 0.2537 5.7135, 8.2117 0.36
RIX:CC(015 x 059) f 4.3715 0.0   1   0.0 0.0 4.3715, 4.3715 -0.85
RIX:CC(016 x 038) f 9.6538 1.1592   6 0.47324 0.1201 7.4352, 10.582 1.61
RIX:CC(017 x 041) f 8.9594 0.29392   3 0.1697 0.0328 8.6325, 9.2018 1.29
RIX:CC(018 x 009) f 8.2119 0.78219   6 0.31933 0.0953 6.7665, 8.8905 0.94
RIX:CC(018 x 065) f 3.9229 0.72123   3 0.4164 0.1839 3.1978, 4.6402 -1.06
RIX:CC(019 x 002) f 9.153 0.87178   4 0.43589 0.0952 8.0367, 10.04 1.38
RIX:CC(025 x 028) f 4.2409 1.5092   3 0.87132 0.3559 2.4993, 5.1648 -0.91
RIX:CC(026 x 034) f 3.6661 0.49577   4 0.24789 0.1352 3.2448, 4.3676 -1.18
RIX:CC(028 x 030) f 7.7423 2.3903   5 1.069 0.3087 3.8765, 10.425 0.72
RIX:CC(032 x 017) f 4.923 1.9957   3 1.1522 0.4054 2.6186, 6.0893 -0.59
RIX:CC(034 x 016) f 5.9272 0.58381   4 0.2919 0.0985 5.0912, 6.3976 -0.13
RIX:CC(035 x 020) f 4.0922 0.0   1   0.0 0.0 4.0922, 4.0922 -0.98
RIX:CC(035 x 071) f 1.363 1.1464   2   0.81063 0.8411 0.55233, 2.1736 -2.25
RIX:CC(037 x 057) f 3.8812 0.0   1   0.0 0.0 3.8812, 3.8812 -1.08
RIX:CC(038 x 013) f 8.4073 0.02934   2   0.02075 0.0035 8.3865, 8.428 1.03
RIX:CC(041 x 016) f 6.3556 0.65156   4 0.32578 0.1025 5.608, 7.1409 0.07
RIX:CC(042 x 017) f 6.1529 3.0781   5 1.3766 0.5003 2.9273, 9.8333 -0.02
RIX:CC(042 x 019) f 4.9887 0.52643   3 0.30394 0.1055 4.441, 5.4909 -0.56
RIX:CC(043 x 037) f 8.1723 0.44725   2   0.31625 0.0547 7.8561, 8.4886 0.92
RIX:CC(051 x 009) f 6.2647 0.06093   3 0.03518 0.0097 6.2205, 6.3342 0.03
RIX:CC(057 x 052) f 9.0086 0.94345   4 0.47173 0.1047 7.6737, 9.8931 1.31
RIX:CC(062 x 046) f 5.2353 0.84026   3 0.48513 0.1605 4.7414, 6.2055 -0.45
RIX:CC(063 x 002) f 5.0189 1.1689   3 0.67485 0.2329 3.7306, 6.0116 -0.55
RIX:CC(075 x 021) f 5.9021 0.0   1   0.0 0.0 5.9021, 5.9021 -0.14
RIX:CC(075 x 035) f 5.8995 1.1098   3 0.64077 0.1881 4.618, 6.5415 -0.14


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
RIX:CC(002 x 021) f 3.8464666667 0.8085926372 5.458754593 2.2341787404
RIX:CC(003 x 051) f 8.9197 0.8085926372 10.5319879263 7.3074120737
RIX:CC(003 x 062) f 10.2633125 0.4951598427 11.2506331845 9.2759918155
RIX:CC(013 x 041) f 5.0385833333 0.571761337 6.1786430592 3.8985236074
RIX:CC(015 x 018) f 6.9626 0.9903196855 8.9372413689 4.9879586311
RIX:CC(016 x 038) f 9.6537666667 0.571761337 10.7938263926 8.5137069408
RIX:CC(017 x 041) f 8.9594333333 0.8085926372 10.5717212596 7.347145407
RIX:CC(018 x 009) f 8.2118833333 0.571761337 9.3519430592 7.0718236074
RIX:CC(018 x 065) f 3.9228666667 0.8085926372 5.535154593 2.3105787404
RIX:CC(019 x 002) f 9.15305 0.7002617652 10.5493323024 7.7567676976
RIX:CC(025 x 028) f 4.2408666667 0.8085926372 5.853154593 2.6285787404
RIX:CC(026 x 034) f 3.666075 0.7002617652 5.0623573024 2.2697926976
RIX:CC(028 x 030) f 7.7423 0.6263331636 8.9911728576 6.4934271424
RIX:CC(032 x 017) f 4.9230333333 0.8085926372 6.5353212596 3.310745407
RIX:CC(034 x 016) f 5.927225 0.7002617652 7.3235073024 4.5309426976
RIX:CC(035 x 071) f 1.362965 0.9903196855 3.3376063689 -0.6116763689
RIX:CC(038 x 013) f 8.40725 0.9903196855 10.3818913689 6.4326086311
RIX:CC(041 x 016) f 6.3556 0.7002617652 7.7518823024 4.9593176976
RIX:CC(042 x 017) f 6.15294 0.6263331636 7.4018128576 4.9040671424
RIX:CC(042 x 019) f 4.9887333333 0.8085926372 6.6010212596 3.376445407
RIX:CC(043 x 037) f 8.17235 0.9903196855 10.1469913689 6.1977086311
RIX:CC(051 x 009) f 6.2647 0.8085926372 7.8769879263 4.6524120737
RIX:CC(057 x 052) f 9.008575 0.7002617652 10.4048573024 7.6122926976
RIX:CC(062 x 046) f 5.2353 0.8085926372 6.8475879263 3.6230120737
RIX:CC(063 x 002) f 5.0189 0.8085926372 6.6311879263 3.4066120737
RIX:CC(075 x 035) f 5.8995333333 0.8085926372 7.5118212596 4.287245407




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA