Project measure / variable:   Noll1   IgG1_d45

ID, description, units MPD:112611   IgG1_d45   immunoglobulin G1 (serum IgG1) area under curve (AUC) post-infection   [AUC]  day 45  
influenza A (H1N1) virus study
Data set, strains Noll1   CC RIX   35 strains     sex: f     age: 8-12 wks
Procedure immunoglobulin quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Noll1 - immunoglobulin G1 (serum IgG1) area under curve (AUC) post-infection day 45



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested35 strains
Mean of the strain means4.5697   AUC
Median of the strain means4.6741   AUC
SD of the strain means± 2.3171
Coefficient of variation (CV)0.507
Min–max range of strain means0.24146   –   8.3059   AUC
Mean sample size per strain3.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 31 534.6439 17.2466 4.6011 < 0.0001
Residuals 82 307.3633 3.7483


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
RIX:CC(002 x 021) f 4.7443 2.5717   3 1.4848 0.5421 2.1103, 7.2488 0.08
RIX:CC(003 x 051) f 3.7729 1.9515   3 1.1267 0.5172 2.0916, 5.9128 -0.34
RIX:CC(003 x 062) f 2.7224 1.3555   8 0.47926 0.4979 0.48606, 5.073 -0.8
RIX:CC(005 x 038) f 6.7855 3.4621   2   2.4481 0.5102 4.3375, 9.2336 0.96
RIX:CC(007 x 075) f 3.7257 0.0   1   0.0 0.0 3.7257, 3.7257 -0.36
RIX:CC(013 x 026) f 4.6741 2.3442   4 1.1721 0.5015 1.5399, 6.9965 0.05
RIX:CC(013 x 041) f 1.567 1.8677   6 0.76248 1.1919 0.07024, 4.7861 -1.3
RIX:CC(015 x 018) f 8.3059 1.368   2   0.96735 0.1647 7.3386, 9.2733 1.61
RIX:CC(015 x 059) f 7.4198 0.0   1   0.0 0.0 7.4198, 7.4198 1.23
RIX:CC(016 x 038) f 6.098 2.3673   6 0.96644 0.3882 1.8494, 8.5855 0.66
RIX:CC(017 x 041) f 7.7526 0.08344   3 0.04817 0.0108 7.6578, 7.815 1.37
RIX:CC(018 x 009) f 4.263 1.8522   6 0.75615 0.4345 1.1729, 6.642 -0.13
RIX:CC(018 x 065) f 3.4884 3.0676   3 1.7711 0.8794 0.8213, 6.8406 -0.47
RIX:CC(019 x 002) f 4.0427 1.6015   4 0.80077 0.3962 2.5304, 5.9675 -0.23
RIX:CC(025 x 028) f 5.7966 0.76928   3 0.44414 0.1327 4.9512, 6.4554 0.53
RIX:CC(026 x 034) f 1.8675 0.75845   4 0.37922 0.4061 1.3017, 2.9785 -1.17
RIX:CC(028 x 030) f 3.657 3.3111   5 1.4808 0.9054 0.20317, 8.0653 -0.39
RIX:CC(032 x 017) f 2.8699 2.3157   3 1.337 0.8069 0.27857, 4.737 -0.73
RIX:CC(034 x 016) f 7.0661 1.3361   4 0.66805 0.1891 5.3588, 8.3743 1.08
RIX:CC(035 x 020) f 5.5992 1.4105   3 0.81434 0.2519 4.5285, 7.1974 0.44
RIX:CC(035 x 071) f 0.24146 0.24905   2   0.17611 1.0314 0.06536, 0.41757 -1.87
RIX:CC(037 x 057) f 8.0731 0.0   1   0.0 0.0 8.0731, 8.0731 1.51
RIX:CC(038 x 013) f 1.1083 0.26722   2   0.18895 0.2411 0.91939, 1.2973 -1.49
RIX:CC(041 x 016) f 0.51565 0.43299   4 0.2165 0.8397 0.09233, 1.0158 -1.75
RIX:CC(042 x 017) f 8.2247 1.715   5 0.76699 0.2085 5.2333, 9.2832 1.58
RIX:CC(042 x 019) f 3.6424 0.72163   3 0.41663 0.1981 2.9648, 4.4012 -0.4
RIX:CC(043 x 037) f 5.3036 1.7656   2   1.2485 0.3329 4.0551, 6.5521 0.32
RIX:CC(051 x 005) f 5.4362 0.28091   3 0.16218 0.0517 5.113, 5.6213 0.37
RIX:CC(051 x 009) f 2.4913 1.2426   3 0.7174 0.4988 1.5921, 3.9092 -0.9
RIX:CC(057 x 052) f 5.0628 3.2736   4 1.6368 0.6466 0.68332, 7.926 0.21
RIX:CC(062 x 046) f 3.7258 3.324   3 1.9191 0.8922 0.26492, 6.8936 -0.36
RIX:CC(063 x 002) f 8.0791 0.42956   3 0.24801 0.0532 7.706, 8.5487 1.51
RIX:CC(074 x 062) f 4.9637 2.3988   3 1.385 0.4833 2.2487, 6.7965 0.17
RIX:CC(075 x 021) f 5.9373 1.0626   2   0.75135 0.179 5.1859, 6.6886 0.59
RIX:CC(075 x 035) f 0.91581 0.33766   3 0.19495 0.3687 0.61697, 1.2821 -1.58


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
RIX:CC(002 x 021) f 4.7443333333 1.1177855364 6.9679648438 2.5207018228
RIX:CC(003 x 051) f 3.7728666667 1.1177855364 5.9964981772 1.5492351562
RIX:CC(003 x 062) f 2.7223825 0.6845010515 4.0840731442 1.3606918558
RIX:CC(005 x 038) f 6.78555 1.369002103 9.5089312883 4.0621687117
RIX:CC(013 x 026) f 4.674075 0.9680306705 6.5997963767 2.7483536233
RIX:CC(013 x 041) f 1.5669983333 0.7903937327 3.1393432533 -0.0053465866
RIX:CC(015 x 018) f 8.30595 1.369002103 11.0293312883 5.5825687117
RIX:CC(016 x 038) f 6.098 0.7903937327 7.6703449199 4.5256550801
RIX:CC(017 x 041) f 7.7525666667 1.1177855364 9.9761981772 5.5289351562
RIX:CC(018 x 009) f 4.2630333333 0.7903937327 5.8353782533 2.6906884134
RIX:CC(018 x 065) f 3.4884 1.1177855364 5.7120315105 1.2647684895
RIX:CC(019 x 002) f 4.042675 0.9680306705 5.9683963767 2.1169536233
RIX:CC(025 x 028) f 5.7966333333 1.1177855364 8.0202648438 3.5730018228
RIX:CC(026 x 034) f 1.867525 0.9680306705 3.7932463767 -0.0581963767
RIX:CC(028 x 030) f 3.656994 0.8658329534 5.3794115617 1.9345764383
RIX:CC(032 x 017) f 2.8698566667 1.1177855364 5.0934881772 0.6462251562
RIX:CC(034 x 016) f 7.066125 0.9680306705 8.9918463767 5.1404036233
RIX:CC(035 x 020) f 5.5992 1.1177855364 7.8228315105 3.3755684895
RIX:CC(035 x 071) f 0.241465 1.369002103 2.9648462883 -2.4819162883
RIX:CC(038 x 013) f 1.108345 1.369002103 3.8317262883 -1.6150362883
RIX:CC(041 x 016) f 0.515655 0.9680306705 2.4413763767 -1.4100663767
RIX:CC(042 x 017) f 8.22466 0.8658329534 9.9470775617 6.5022424383
RIX:CC(042 x 019) f 3.6424333333 1.1177855364 5.8660648438 1.4188018228
RIX:CC(043 x 037) f 5.3036 1.369002103 8.0269812883 2.5802187117
RIX:CC(051 x 005) f 5.4362333333 1.1177855364 7.6598648438 3.2126018228
RIX:CC(051 x 009) f 2.4913333333 1.1177855364 4.7149648438 0.2677018228
RIX:CC(057 x 052) f 5.06283 0.9680306705 6.9885513767 3.1371086233
RIX:CC(062 x 046) f 3.72584 1.1177855364 5.9494715105 1.5022084895
RIX:CC(063 x 002) f 8.0791 1.1177855364 10.3027315105 5.8554684895
RIX:CC(074 x 062) f 4.9637 1.1177855364 7.1873315105 2.7400684895
RIX:CC(075 x 021) f 5.93725 1.369002103 8.6606312883 3.2138687117
RIX:CC(075 x 035) f 0.91581 1.1177855364 3.1394415105 -1.3078215105




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA