Project measure / variable:   Noll1   IgM_d45

ID, description, units MPD:112606   IgM_d45   immunoglobulin M (serum IgM) area under curve (AUC) post-infection   [AUC]  day 45  
influenza A (H1N1) virus study
Data set, strains Noll1   CC RIX   33 strains     sex: f     age: 8-12 wks
Procedure immunoglobulin quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Noll1 - immunoglobulin M (serum IgM) area under curve (AUC) post-infection day 45



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested33 strains
Mean of the strain means0.17987   AUC
Median of the strain means0.11084   AUC
SD of the strain means± 0.23711
Coefficient of variation (CV)1.3182
Min–max range of strain means0.03044   –   1.3215   AUC
Mean sample size per strain3.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 31 11.7401 0.3787 1.8322 0.0161
Residuals 81 16.743 0.2067


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
RIX:CC(002 x 021) f 0.2111 0.17331   3 0.10006 0.821 0.04025, 0.38677 0.13
RIX:CC(003 x 051) f 0.18902 0.03545   3 0.02047 0.1875 0.14911, 0.21685 0.04
RIX:CC(003 x 062) f 1.3215 1.3502   8 0.47738 1.0218 0.36628, 4.134 4.81
RIX:CC(005 x 038) f 0.05859 0.02668   3 0.01541 0.4554 0.03921, 0.08902 -0.51
RIX:CC(007 x 075) f 0.05338 0.0   1   0.0 0.0 0.05338, 0.05338 -0.53
RIX:CC(013 x 026) f 0.10229 0.03781   4 0.01891 0.3697 0.07166, 0.15309 -0.33
RIX:CC(013 x 041) f 0.05355 0.0061638   3 0.00355867 0.1151 0.04991, 0.06067 -0.53
RIX:CC(015 x 018) f 0.12717 0.07066   2   0.04996 0.5557 0.0772, 0.17713 -0.22
RIX:CC(016 x 038) f 0.31093 0.17576   6 0.07175 0.5653 0.16126, 0.65442 0.55
RIX:CC(017 x 041) f 0.34694 0.26521   3 0.15312 0.7644 0.13283, 0.64361 0.7
RIX:CC(018 x 009) f 0.14259 0.11706   6 0.04779 0.821 0.06213, 0.37172 -0.16
RIX:CC(018 x 065) f 0.15604 0.03827   3 0.0221 0.2453 0.11503, 0.1908 -0.1
RIX:CC(019 x 002) f 0.05469 0.00765634   4 0.00382817 0.14 0.04739, 0.0652 -0.53
RIX:CC(025 x 028) f 0.17729 0.0505   3 0.02916 0.2848 0.14446, 0.23544 -0.01
RIX:CC(026 x 034) f 0.05566 0.00887342   4 0.00443671 0.1594 0.04525, 0.06688 -0.52
RIX:CC(028 x 030) f 0.44941 0.85462   5 0.3822 1.9016 0.0446, 1.9778 1.14
RIX:CC(032 x 017) f 0.03044 0.0014577   3 0.00084161 0.0479 0.02876, 0.03137 -0.63
RIX:CC(034 x 016) f 0.11084 0.01955   4 0.00977738 0.1764 0.08642, 0.13328 -0.29
RIX:CC(035 x 020) f 0.10575 0.1062   3 0.06132 1.0043 0.04338, 0.22838 -0.31
RIX:CC(035 x 071) f 0.13268 0.06029   2   0.04263 0.4544 0.09005, 0.17531 -0.2
RIX:CC(038 x 013) f 0.09975 0.02198   2   0.01554 0.2204 0.0842, 0.11529 -0.34
RIX:CC(041 x 016) f 0.03426 0.01674   4 0.00837141 0.4887 0.0164, 0.04976 -0.61
RIX:CC(042 x 017) f 0.31248 0.21926   5 0.09806 0.7017 0.06879, 0.52599 0.56
RIX:CC(042 x 019) f 0.03932 0.00708843   3 0.00409251 0.1803 0.03459, 0.04747 -0.59
RIX:CC(043 x 037) f 0.13222 0.03671   2   0.02596 0.2776 0.10627, 0.15818 -0.2
RIX:CC(051 x 005) f 0.0729 0.00238563   3 0.00137734 0.0327 0.07048, 0.07525 -0.45
RIX:CC(051 x 009) f 0.04812 0.02604   3 0.01504 0.5412 0.01975, 0.07094 -0.56
RIX:CC(057 x 052) f 0.17501 0.07041   4 0.0352 0.4023 0.10583, 0.27015 -0.02
RIX:CC(062 x 046) f 0.06387 0.01492   4 0.00745782 0.2335 0.04507, 0.07929 -0.49
RIX:CC(063 x 002) f 0.05661 0.0081424   3 0.00470102 0.1438 0.04721, 0.06158 -0.52
RIX:CC(074 x 062) f 0.11361 0.01869   3 0.01079 0.1645 0.09324, 0.12998 -0.28
RIX:CC(075 x 021) f 0.0795 0.0173   2   0.01224 0.2176 0.06727, 0.09174 -0.42
RIX:CC(075 x 035) f 0.51809 0.4321   3 0.24948 0.834 0.18517, 1.0064 1.43


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
RIX:CC(002 x 021) f 0.2111033333 0.2624904898 0.733377071 -0.3111704043
RIX:CC(003 x 051) f 0.1890233333 0.2624904898 0.711297071 -0.3332504043
RIX:CC(003 x 062) f 1.32146 0.1607419406 1.6412860408 1.0016339592
RIX:CC(005 x 038) f 0.0585866667 0.2624904898 0.5808604043 -0.463687071
RIX:CC(013 x 026) f 0.102285 0.2273234324 0.5545873245 -0.3500173245
RIX:CC(013 x 041) f 0.0535533333 0.2624904898 0.575827071 -0.4687204043
RIX:CC(015 x 018) f 0.127165 0.3214838812 0.7668170816 -0.5124870816
RIX:CC(016 x 038) f 0.3109266667 0.1856088053 0.6802299682 -0.0583766348
RIX:CC(017 x 041) f 0.3469433333 0.2624904898 0.869217071 -0.1753304043
RIX:CC(018 x 009) f 0.1425866667 0.1856088053 0.5118899682 -0.2267166348
RIX:CC(018 x 065) f 0.1560433333 0.2624904898 0.678317071 -0.3662304043
RIX:CC(019 x 002) f 0.05469 0.2273234324 0.5069923245 -0.3976123245
RIX:CC(025 x 028) f 0.17729 0.2624904898 0.6995637376 -0.3449837376
RIX:CC(026 x 034) f 0.0556575 0.2273234324 0.5079598245 -0.3966448245
RIX:CC(028 x 030) f 0.449412 0.2033242591 0.8539634976 0.0448605024
RIX:CC(032 x 017) f 0.03044 0.2624904898 0.5527137376 -0.4918337376
RIX:CC(034 x 016) f 0.11084 0.2273234324 0.5631423245 -0.3414623245
RIX:CC(035 x 020) f 0.1057533333 0.2624904898 0.628027071 -0.4165204043
RIX:CC(035 x 071) f 0.13268 0.3214838812 0.7723320816 -0.5069720816
RIX:CC(038 x 013) f 0.099745 0.3214838812 0.7393970816 -0.5399070816
RIX:CC(041 x 016) f 0.03426 0.2273234324 0.4865623245 -0.4180423245
RIX:CC(042 x 017) f 0.312476 0.2033242591 0.7170274976 -0.0920754976
RIX:CC(042 x 019) f 0.03932 0.2624904898 0.5615937376 -0.4829537376
RIX:CC(043 x 037) f 0.132225 0.3214838812 0.7718770816 -0.5074270816
RIX:CC(051 x 005) f 0.0728966667 0.2624904898 0.5951704043 -0.449377071
RIX:CC(051 x 009) f 0.0481233333 0.2624904898 0.570397071 -0.4741504043
RIX:CC(057 x 052) f 0.1750125 0.2273234324 0.6273148245 -0.2772898245
RIX:CC(062 x 046) f 0.063865 0.2273234324 0.5161673245 -0.3884373245
RIX:CC(063 x 002) f 0.0566066667 0.2624904898 0.5788804043 -0.465667071
RIX:CC(074 x 062) f 0.1136133333 0.2624904898 0.635887071 -0.4086604043
RIX:CC(075 x 021) f 0.079505 0.3214838812 0.7191570816 -0.5601470816
RIX:CC(075 x 035) f 0.51809 0.2624904898 1.0403637376 -0.0041837376




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA