Project measure / variable:   Noll1   IgM_d10

ID, description, units MPD:112603   IgM_d10   immunoglobulin M (serum IgM) area under curve (AUC) post-infection   [AUC]  day 10  
influenza A (H1N1) virus study
Data set, strains Noll1   CC RIX   38 strains     sex: f     age: 8-12 wks
Procedure immunoglobulin quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Noll1 - immunoglobulin M (serum IgM) area under curve (AUC) post-infection day 10



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested38 strains
Mean of the strain means1.0485   AUC
Median of the strain means0.77828   AUC
SD of the strain means± 0.86193
Coefficient of variation (CV)0.8221
Min–max range of strain means0.05584   –   3.0552   AUC
Mean sample size per strain3.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 32 62.3119 1.9472 4.3463 < 0.0001
Residuals 96 43.01 0.448


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
RIX:CC(002 x 021) f 0.21033 0.25674   3 0.14823 1.2206 0.03131, 0.50449 -0.97
RIX:CC(003 x 051) f 0.23082 0.13337   3 0.077 0.5778 0.14902, 0.38472 -0.95
RIX:CC(005 x 020) f 1.7525 0.21248   3 0.12267 0.1212 1.5256, 1.9468 0.82
RIX:CC(007 x 075) f 1.2093 0.29405   4 0.14702 0.2431 0.88944, 1.5728 0.19
RIX:CC(013 x 026) f 0.69731 0.26344   5 0.11781 0.3778 0.40193, 1.1126 -0.41
RIX:CC(013 x 041) f 0.13712 0.06207   8 0.02194 0.4527 0.04919, 0.23148 -1.06
RIX:CC(015 x 018) f 2.9653 0.0   1   0.0 0.0 2.9653, 2.9653 2.22
RIX:CC(015 x 059) f 0.26724 0.12263   3 0.0708 0.4589 0.15504, 0.39815 -0.91
RIX:CC(016 x 038) f 2.4215 0.78088   3 0.45084 0.3225 1.5739, 3.1117 1.59
RIX:CC(017 x 041) f 0.51749 0.37731   2   0.2668 0.7291 0.25069, 0.78429 -0.62
RIX:CC(018 x 009) f 1.7188 0.0   1   0.0 0.0 1.7188, 1.7188 0.78
RIX:CC(018 x 065) f 1.7897 0.25421   3 0.14677 0.142 1.6329, 2.083 0.86
RIX:CC(019 x 002) f 1.3407 1.4445   6 0.58971 1.0774 0.12674, 3.4041 0.34
RIX:CC(025 x 028) f 0.90911 0.53776   4 0.26888 0.5915 0.10472, 1.234 -0.16
RIX:CC(026 x 034) f 1.0495 0.96695   4 0.48348 0.9214 0.37113, 2.4651 0.0
RIX:CC(028 x 030) f 0.35849 0.1183   5 0.0529 0.33 0.22088, 0.49975 -0.8
RIX:CC(032 x 013) f 0.42452 0.26288   7 0.09936 0.6193 0.16807, 0.92843 -0.72
RIX:CC(032 x 017) f 1.7479 1.1156   3 0.64408 0.6383 0.51198, 2.6804 0.81
RIX:CC(034 x 016) f 2.8438 0.28154   3 0.16255 0.099 2.5409, 3.0975 2.08
RIX:CC(035 x 071) f 0.46514 0.29232   3 0.16877 0.6285 0.24145, 0.7959 -0.68
RIX:CC(037 x 046) f 0.06069 0.0102   3 0.00588763 0.168 0.05036, 0.07075 -1.15
RIX:CC(037 x 057) f 0.57134 0.23036   3 0.133 0.4032 0.3569, 0.81486 -0.55
RIX:CC(038 x 013) f 0.22314 0.09751   3 0.0563 0.437 0.156, 0.33498 -0.96
RIX:CC(041 x 016) f 0.72484 0.91485   3 0.52819 1.2621 0.05372, 1.7669 -0.38
RIX:CC(042 x 019) f 2.6172 0.0   1   0.0 0.0 2.6172, 2.6172 1.82
RIX:CC(042 x 025) f 1.0536 0.7638   3 0.44098 0.725 0.17771, 1.5812 0.01
RIX:CC(043 x 037) f 0.53802 0.18346   9 0.06115 0.341 0.279, 0.88201 -0.59
RIX:CC(051 x 005) f 1.3814 1.9801   4 0.99006 1.4334 0.23031, 4.3464 0.39
RIX:CC(051 x 009) f 3.0552 0.1475   2   0.1043 0.0483 2.9509, 3.1595 2.33
RIX:CC(052 x 007) f 1.5478 1.3673   3 0.78944 0.8834 0.2574, 2.9809 0.58
RIX:CC(057 x 052) f 0.29797 0.20983   3 0.12115 0.7042 0.15287, 0.53857 -0.87
RIX:CC(058 x 022) f 0.83172 0.0   1   0.0 0.0 0.83172, 0.83172 -0.25
RIX:CC(062 x 046) f 0.46543 0.1623   4 0.08115 0.3487 0.29026, 0.68018 -0.68
RIX:CC(063 x 002) f 0.05584 0.02386   4 0.01193 0.4273 0.03478, 0.08976 -1.15
RIX:CC(074 x 058) f 0.52728 0.21957   3 0.12677 0.4164 0.38998, 0.78052 -0.6
RIX:CC(074 x 062) f 0.20957 0.0   1   0.0 0.0 0.20957, 0.20957 -0.97
RIX:CC(075 x 021) f 1.2127 0.38954   8 0.13772 0.3212 0.73686, 1.8022 0.19
RIX:CC(075 x 035) f 1.413 1.785   2   1.2622 1.2633 0.15082, 2.6752 0.42


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
RIX:CC(002 x 021) f 0.2103333333 0.3864457156 0.977422016 -0.5567553494
RIX:CC(003 x 051) f 0.23082 0.3864457156 0.9979086827 -0.5362686827
RIX:CC(005 x 020) f 1.7524666667 0.3864457156 2.5195553494 0.985377984
RIX:CC(007 x 075) f 1.209335 0.3346718069 1.8736532862 0.5450167138
RIX:CC(013 x 026) f 0.697314 0.2993395641 1.2914983386 0.1031296614
RIX:CC(013 x 041) f 0.13712125 0.2366487041 0.606865215 -0.332622715
RIX:CC(015 x 059) f 0.2672433333 0.3864457156 1.034332016 -0.4998453494
RIX:CC(016 x 038) f 2.4214666667 0.3864457156 3.1885553494 1.654377984
RIX:CC(017 x 041) f 0.51749 0.4732974082 1.4569779301 -0.4219979301
RIX:CC(018 x 065) f 1.7897 0.3864457156 2.5567886827 1.0226113173
RIX:CC(019 x 002) f 1.340685 0.2732583861 1.8830986093 0.7982713907
RIX:CC(025 x 028) f 0.909105 0.3346718069 1.5734232862 0.2447867138
RIX:CC(026 x 034) f 1.049455 0.3346718069 1.7137732862 0.3851367138
RIX:CC(028 x 030) f 0.358486 0.2993395641 0.9526703386 -0.2356983386
RIX:CC(032 x 013) f 0.4245157143 0.2529881062 0.9266931362 -0.0776617076
RIX:CC(032 x 017) f 1.74786 0.3864457156 2.5149486827 0.9807713173
RIX:CC(034 x 016) f 2.8438 0.3864457156 3.6108886827 2.0767113173
RIX:CC(035 x 071) f 0.4651433333 0.3864457156 1.232232016 -0.3019453494
RIX:CC(037 x 046) f 0.06069 0.3864457156 0.8277786827 -0.7063986827
RIX:CC(037 x 057) f 0.5713366667 0.3864457156 1.3384253494 -0.195752016
RIX:CC(038 x 013) f 0.2231366667 0.3864457156 0.9902253494 -0.543952016
RIX:CC(041 x 016) f 0.72484 0.3864457156 1.4919286827 -0.0422486827
RIX:CC(042 x 025) f 1.05357 0.3864457156 1.8206586827 0.2864813173
RIX:CC(043 x 037) f 0.5380233333 0.2231145379 0.9809021908 0.0951444759
RIX:CC(051 x 005) f 1.38139 0.3346718069 2.0457082862 0.7170717138
RIX:CC(051 x 009) f 3.0552 0.4732974082 3.9946879301 2.1157120699
RIX:CC(052 x 007) f 1.5478 0.3864457156 2.3148886827 0.7807113173
RIX:CC(057 x 052) f 0.2979733333 0.3864457156 1.065062016 -0.4691153494
RIX:CC(062 x 046) f 0.4654325 0.3346718069 1.1297507862 -0.1988857862
RIX:CC(063 x 002) f 0.05584 0.3346718069 0.7201582862 -0.6084782862
RIX:CC(074 x 058) f 0.52728 0.3864457156 1.2943686827 -0.2398086827
RIX:CC(075 x 021) f 1.21271375 0.2366487041 1.682457715 0.742969785
RIX:CC(075 x 035) f 1.41301 0.4732974082 2.3524979301 0.4735220699




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA