Project measure / variable:   CSNA03   amplitude_in

ID, description, units MPD:112541   amplitude_in   peak-to-trough, indicating level of synchronization in circadian rhythm (max counts/s), in fibroblast cultures, founders   [n/s]  
Data set, strains CSNA03   inbred w/CC8   8 strains     sex: both     age: 8-12wks
Procedure in vitro assay
Ontology mappings

  STRAIN COMPARISON PLOT
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CSNA03 - peak-to-trough, indicating level of synchronization in circadian rhythm (max counts/s), in fibroblast cultures, founders



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means298.6   n/s 368.4   n/s
Median of the strain means279.2   n/s 381.7   n/s
SD of the strain means± 165.1 ± 202.8
Coefficient of variation (CV)0.5528 0.5504
Min–max range of strain means91.91   –   590.6   n/s 69.05   –   718.7   n/s
Mean sample size per strain9.4   mice 9.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 118830.458 118830.458 1.5593 0.214
strain 7 3682638.1392 526091.1627 6.9032 < 0.0001
sex:strain 7 551819.3334 78831.3333 1.0344 0.4103
Residuals 131 9983439.4789 76209.4617


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 316.3 212.7   10 67.27 0.6726 83.93, 623.5 0.11
129S1/SvImJ m 502.2 589.2   9 196.4 1.1733 39.663, 1763.0 0.66
A/J f 113.7 60.24   9 20.08 0.53 34.489, 252.5 -1.12
A/J m 318.6 198.8   9 66.27 0.6239 69.56, 563.3 -0.25
C57BL/6J f 237.7 109.5   10 34.612 0.4604 102.0, 371.7 -0.37
C57BL/6J m 218.5 154.9   10 48.979 0.7088 6.914, 469.3 -0.74
CAST/EiJ f 425.2 352.9   10 111.6 0.83 28.163, 1225.0 0.77
CAST/EiJ m 444.8 297.0   10 93.93 0.6677 47.289, 872.8 0.38
NOD/ShiLtJ f 91.91 14.714   9 4.9047 0.1601 70.89, 116.2 -1.25
NOD/ShiLtJ m 69.05 22.921   9 7.6403 0.3319 20.223, 101.2 -1.48
NZO/HlLtJ f 242.1 129.4   8 45.751 0.5345 49.372, 443.2 -0.34
NZO/HlLtJ m 449.6 308.4   7 116.6 0.686 50.16, 824.7 0.4
PWK/PhJ f 371.5 202.6   10 64.06 0.5453 30.887, 649.6 0.44
PWK/PhJ m 226.1 132.9   10 42.015 0.5877 16.119, 365.0 -0.7
WSB/EiJ f 590.6 478.1   9 159.4 0.8095 117.7, 1331.0 1.77
WSB/EiJ m 718.7 407.8   8 144.2 0.5674 116.8, 1140.0 1.73


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 316.273 87.2980307174 488.969328764 143.576671236
129S1/SvImJ m 502.2292222222 92.0202041047 684.26713637 320.1913080744
A/J f 113.6654444444 92.0202041047 295.7033585923 -68.3724697034
A/J m 318.6377777778 92.0202041047 500.6756919256 136.59986363
C57BL/6J f 237.73 87.2980307174 410.426328764 65.033671236
C57BL/6J m 218.5208 87.2980307174 391.217128764 45.824471236
CAST/EiJ f 425.2083 87.2980307174 597.904628764 252.511971236
CAST/EiJ m 444.8329 87.2980307174 617.529228764 272.136571236
NOD/ShiLtJ f 91.9066666667 92.0202041047 273.9445808145 -90.1312474812
NOD/ShiLtJ m 69.0514444444 92.0202041047 251.0893585923 -112.9864697034
NZO/HlLtJ f 242.109 97.6021654929 435.1893652905 49.0286347095
NZO/HlLtJ m 449.6371428571 104.3411038519 656.0487357229 243.2255499914
PWK/PhJ f 371.5121 87.2980307174 544.208428764 198.815771236
PWK/PhJ m 226.0738 87.2980307174 398.770128764 53.377471236
WSB/EiJ f 590.6222222222 92.0202041047 772.66013637 408.5843080744
WSB/EiJ m 718.6875 97.6021654929 911.7678652905 525.6071347095


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 409.2511111111 63.4205489778 534.7120852782 283.790136944
A/J both 216.1516111111 65.0681103286 344.8718546381 87.4313675841
C57BL/6J both 228.1254 61.7290295045 350.240145155 106.010654845
CAST/EiJ both 435.0206 61.7290295045 557.135345155 312.905854845
NOD/ShiLtJ both 80.4790555556 65.0681103286 209.1992990825 -48.2411879714
NZO/HlLtJ both 345.8730714286 71.4374703184 487.1934283575 204.5527144996
PWK/PhJ both 298.79295 61.7290295045 420.907695155 176.678204845
WSB/EiJ both 654.6548611111 67.0706729361 787.3366511654 521.9730710569




  GWAS USING LINEAR MIXED MODELS