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Project measure / variable:   McLachlan1   Hamp1_12

ID, description, units MPD:112470   Hamp1_12   liver Hamp1 mRNA (encodes hepcidin) normalized to actin mRNA after 6 wks on diet    12 ppm  
iron-containing diet study
Data set, strains McLachlan1   inbred   6 strains     sex: m     age: 10wks
Procedure RNA expression profiling
Ontology mappings


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  STRAIN COMPARISON PLOT
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McLachlan1 - liver Hamp1 mRNA (encodes hepcidin) normalized to actin mRNA after 6 wks on diet 12 ppm



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested6 strains
Mean of the strain means-8.5787   None
Median of the strain means-8.4265   None
SD of the strain means± 1.2601
Coefficient of variation (CV)-0.1469
Min–max range of strain means-10.58   –   -7.1098   None
Mean sample size per strain5.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 5 45.5506 9.1101 3.2193 0.0202
Residuals 28 79.2369 2.8299


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J m -7.5859 1.3699   4 0.68497 -0.1806 -8.8975, -6.3569 0.79
AKR/J m -10.58 1.5085   6 0.61585 -0.1426 -12.356, -8.4847 -1.59
BALB/cJ m -8.1442 1.5502   6 0.63285 -0.1903 -9.8577, -5.6395 0.34
C3H/HeJ m -8.7088 1.287   6 0.52543 -0.1478 -10.238, -7.099 -0.1
C57BL/6J m -7.1098 2.6786   6 1.0935 -0.3767 -9.8821, -2.5843 1.17
DBA/2J m -9.3434 1.1006   6 0.4493 -0.1178 -10.835, -7.6659 -0.61


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m -7.585875 0.8411134768 -5.862932147 -9.308817853
AKR/J m -10.5802 0.686766278 -9.1734230514 -11.9869769486
BALB/cJ m -8.14425 0.686766278 -6.7374730514 -9.5510269486
C3H/HeJ m -8.70875 0.686766278 -7.3019730514 -10.1155269486
C57BL/6J m -7.1098333333 0.686766278 -5.7030563847 -8.5166102819
DBA/2J m -9.3433833333 0.686766278 -7.9366063847 -10.7501602819




  GWAS USING LINEAR MIXED MODELS