McLachlan1: Hamp1 mRNA and plasma hepcidin levels in 6 inbred strains and 3 recombinant inbred strains of mice fed a diet of insufficient, sufficient, or high levels of iron (2017) [Pending]

McLachlan S, Page KE, Lee SM, Loguinov A, Valore E, Hui ST, Jung G, Zhou J, Lusis AJ, Fuqua B, Ganz T, Nemeth E, Vulpe CD. Hamp1 mRNA and plasma hepcidin levels are influenced by sex and strain but do not predict tissue iron levels in inbred mice. Am J Physiol Gastrointest Liver Physiol. 2017 Nov 1;313(5):G511-G523. doi: 10.1152/ajpgi.00307.2016. Epub 2017 Aug 10.   PubMed 28798083     FullText


         
McLachlan1 downloads
• Download McLachlan1 project data set     strain means, as uploaded
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Investigators Stela McLachlan       University of Edinburgh,  Edinburgh UK
Chris D Vulpe       University of Florida,  Gainesville, FL
Participants Page KE, Lee SM, Loguinov A, Valore E, Hui ST, Jung G, Zhou J, Lusis AJ, Fuqua B, Ganz T, Nemeth E
ContactStela McLachlan     stela.mclachlan@ed.ac.uk     Lab web site
Funding Provided ByNIH GM83198, HL28481
Project type Phenotype strain survey data set
MPD identifiersMcLachlan1     MPD:1045
Data changelog This project has not yet been released.
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Experimental groups in this study:
• Iron-deficient diet     • iron-sufficient diet (control)     • high-iron diet    

Procedures conducted:
• RNA expression profiling  Hamp1 mRNA levels in liver (encodes hepcidin).
• biomarker quantification  Plasma hepcidin levels.

Mice: inbred   9 strains   ♂   age 10wks   3 experimental groups


No phenotype measures have been accessioned yet.