Project measure / variable:   Auwerx1   vo2_basal_wheel_HFD

ID, description, units MPD:111325   vo2_basal_wheel_HFD   basal oxygen consumption, after voluntary wheel running test   [mL/kg/min]  HFD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   56 strains     sex: m     age: 25wks
Procedure monitoring system
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  STRAIN COMPARISON PLOT
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Auwerx1 - basal oxygen consumption, after voluntary wheel running test HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested56 strains
Mean of the strain means72.83   mL/kg/min
Median of the strain means71.66   mL/kg/min
SD of the strain means± 12.923
Coefficient of variation (CV)0.1774
Min–max range of strain means55.26   –   104.3   mL/kg/min
Mean sample size per strain4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 55 41367.168 752.1303 8.5007 < 0.0001
Residuals 189 16722.5375 88.479


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 80.8 13.075   5 5.8472 0.1618 62.0, 97.75 0.62
BXD100 m 76.17 11.622   5 5.1975 0.1526 65.75, 93.83 0.26
BXD101 m 72.2 8.1335   4 4.0667 0.1127 62.8, 81.7 -0.05
BXD11 m 96.36 7.8615   5 3.5158 0.0816 87.4, 109.0 1.82
BXD12 m 93.41 7.4425   5 3.3284 0.0797 86.0, 104.4 1.59
BXD16 m 56.63 4.6582   5 2.0832 0.0823 51.75, 62.9 -1.25
BXD2 m 74.13 7.9913   5 3.5738 0.1078 68.6, 88.0 0.1
BXD27 m 89.08 15.648   4 7.8241 0.1757 73.5, 110.8 1.26
BXD32 m 79.67 25.073   3 14.476 0.3147 64.3, 108.6 0.53
BXD34 m 83.67 7.4172   5 3.3171 0.0887 73.6, 90.0 0.84
BXD39 m 67.02 5.2093   5 2.3297 0.0777 58.1, 71.5 -0.45
BXD40 m 84.4 10.84   4 5.42 0.1284 68.3, 91.3 0.9
BXD43 m 73.6 7.7117   3 4.4523 0.1048 65.0, 79.9 0.06
BXD44 m 61.08 6.5325   8 2.3096 0.1069 52.83, 70.67 -0.91
BXD45 m 93.82 2.5845   4 1.2922 0.0275 91.1, 97.33 1.62
BXD48 m 62.72 9.635   5 4.3089 0.1536 50.0, 74.42 -0.78
BXD48a m 59.67 8.4031   3 4.8515 0.1408 52.17, 68.75 -1.02
BXD49 m 55.26 11.43   4 5.7152 0.2068 46.75, 71.9 -1.36
BXD50 m 71.13 4.1982   5 1.8775 0.059 66.1, 76.7 -0.13
BXD51 m 59.52 10.006   4 5.003 0.1681 46.33, 68.1 -1.03
BXD53 m 74.18 8.1417   5 3.6411 0.1098 64.5, 86.7 0.1
BXD55 m 92.81 9.0917   4 4.5458 0.098 82.42, 102.4 1.55
BXD56 m 77.6 1.8385   2   1.3 0.0237 76.3, 78.9 0.37
BXD6 m 68.04 7.1204   5 3.1844 0.1046 56.7, 74.25 -0.37
BXD60 m 56.18 3.1068   5 1.3894 0.0553 53.4, 61.4 -1.29
BXD61 m 69.17 2.3702   5 1.06 0.0343 67.17, 72.17 -0.28
BXD62 m 64.73 5.4813   4 2.7406 0.0847 58.5, 71.5 -0.63
BXD63 m 66.04 8.1883   2   5.79 0.124 60.25, 71.83 -0.53
BXD64 m 67.95 4.8059   4 2.4029 0.0707 64.2, 74.9 -0.38
BXD65 m 55.36 3.9084   4 1.9542 0.0706 52.33, 61.1 -1.35
BXD65a m 60.3 3.2383   4 1.6192 0.0537 56.7, 64.3 -0.97
BXD66 m 55.72 2.7097   5 1.2118 0.0486 53.42, 60.25 -1.32
BXD67 m 60.9 10.186   5 4.5553 0.1673 50.58, 75.92 -0.92
BXD68 m 79.65 8.6219   4 4.3109 0.1082 69.9, 90.8 0.53
BXD69 m 73.05 8.3241   5 3.7226 0.114 59.7, 82.75 0.02
BXD70 m 103.4 19.258   4 9.629 0.1863 82.1, 123.1 2.37
BXD71 m 68.75 4.4048   3 2.5431 0.0641 63.7, 71.8 -0.32
BXD73 m 82.97 3.859   4 1.9295 0.0465 78.8, 86.42 0.78
BXD73a m 63.94 7.7643   4 3.8821 0.1214 52.58, 70.08 -0.69
BXD73b m 64.14 6.7441   5 3.0161 0.1051 55.3, 73.2 -0.67
BXD75 m 76.88 6.5779   5 2.9417 0.0856 69.75, 84.92 0.31
BXD77 m 74.66 21.462   5 9.5983 0.2875 42.8, 101.3 0.14
BXD79 m 61.85 5.2883   5 2.365 0.0855 53.08, 66.5 -0.85
BXD8 m 104.3 14.185   5 6.3437 0.1361 83.91, 120.8 2.44
BXD81 m 58.27 4.0797   4 2.0399 0.07 55.42, 64.3 -1.13
BXD83 m 74.92 6.7869   4 3.3934 0.0906 69.0, 84.42 0.16
BXD84 m 69.51 12.049   3 6.9566 0.1733 56.2, 79.67 -0.26
BXD85 m 56.4 5.5743   4 2.7872 0.0988 51.8, 64.3 -1.27
BXD87 m 86.97 13.823   4 6.9113 0.1589 79.83, 107.7 1.09
BXD89 m 79.97 6.1402   4 3.0701 0.0768 73.0, 87.7 0.55
BXD90 m 74.92 5.9079   4 2.954 0.0789 68.1, 80.5 0.16
BXD95 m 66.08 15.0   5 6.7083 0.227 51.5, 84.33 -0.52
BXD98 m 55.68 6.5717   5 2.9389 0.118 49.7, 65.2 -1.33
BXD99 m 65.2 6.6914   5 2.9925 0.1026 57.08, 72.75 -0.59
C57BL/6J m 81.28 6.6289   4 3.3145 0.0816 75.5, 90.8 0.65
DBA/2J m 96.33 14.462   5 6.4675 0.1501 81.57, 115.6 1.82


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 80.8 4.2066384316 89.0979942697 72.5020057303
BXD100 m 76.166 4.2066384316 84.4639942697 67.8680057303
BXD101 m 72.2 4.7031647449 81.477439632 62.922560368
BXD11 m 96.36 4.2066384316 104.6579942697 88.0620057303
BXD12 m 93.41 4.2066384316 101.7079942697 85.1120057303
BXD16 m 56.628 4.2066384316 64.9259942697 48.3300057303
BXD2 m 74.13 4.2066384316 82.4279942697 65.8320057303
BXD27 m 89.075 4.7031647449 98.352439632 79.797560368
BXD32 m 79.6666666667 5.430746863 90.3793312045 68.9540021288
BXD34 m 83.666 4.2066384316 91.9639942697 75.3680057303
BXD39 m 67.02 4.2066384316 75.3179942697 58.7220057303
BXD40 m 84.4 4.7031647449 93.677439632 75.122560368
BXD43 m 73.6 5.430746863 84.3126645378 62.8873354622
BXD44 m 61.085 3.3256396842 67.6451404758 54.5248595242
BXD45 m 93.8175 4.7031647449 103.094939632 84.540060368
BXD48 m 62.724 4.2066384316 71.0219942697 54.4260057303
BXD48a m 59.6666666667 5.430746863 70.3793312045 48.9540021288
BXD49 m 55.2625 4.7031647449 64.539939632 45.985060368
BXD50 m 71.134 4.2066384316 79.4319942697 62.8360057303
BXD51 m 59.525 4.7031647449 68.802439632 50.247560368
BXD53 m 74.18 4.2066384316 82.4779942697 65.8820057303
BXD55 m 92.8125 4.7031647449 102.089939632 83.535060368
BXD56 m 77.6 6.6512793683 90.7202809517 64.4797190483
BXD6 m 68.044 4.2066384316 76.3419942697 59.7460057303
BXD60 m 56.18 4.2066384316 64.4779942697 47.8820057303
BXD61 m 69.172 4.2066384316 77.4699942697 60.8740057303
BXD62 m 64.7325 4.7031647449 74.009939632 55.455060368
BXD63 m 66.04 6.6512793683 79.1602809517 52.9197190483
BXD64 m 67.95 4.7031647449 77.227439632 58.672560368
BXD65 m 55.3575 4.7031647449 64.634939632 46.080060368
BXD65a m 60.3 4.7031647449 69.577439632 51.022560368
BXD66 m 55.716 4.2066384316 64.0139942697 47.4180057303
BXD67 m 60.898 4.2066384316 69.1959942697 52.6000057303
BXD68 m 79.65 4.7031647449 88.927439632 70.372560368
BXD69 m 73.05 4.2066384316 81.3479942697 64.7520057303
BXD70 m 103.395 4.7031647449 112.672439632 94.117560368
BXD71 m 68.75 5.430746863 79.4626645378 58.0373354622
BXD73 m 82.97 4.7031647449 92.247439632 73.692560368
BXD73a m 63.935 4.7031647449 73.212439632 54.657560368
BXD73b m 64.14 4.2066384316 72.4379942697 55.8420057303
BXD75 m 76.884 4.2066384316 85.1819942697 68.5860057303
BXD77 m 74.66 4.2066384316 82.9579942697 66.3620057303
BXD79 m 61.85 4.2066384316 70.1479942697 53.5520057303
BXD8 m 104.262 4.2066384316 112.5599942697 95.9640057303
BXD81 m 58.2675 4.7031647449 67.544939632 48.990060368
BXD83 m 74.9175 4.7031647449 84.194939632 65.640060368
BXD84 m 69.5133333333 5.430746863 80.2259978712 58.8006687955
BXD85 m 56.4 4.7031647449 65.677439632 47.122560368
BXD87 m 86.9675 4.7031647449 96.244939632 77.690060368
BXD89 m 79.975 4.7031647449 89.252439632 70.697560368
BXD90 m 74.9225 4.7031647449 84.199939632 65.645060368
BXD95 m 66.076 4.2066384316 74.3739942697 57.7780057303
BXD98 m 55.68 4.2066384316 63.9779942697 47.3820057303
BXD99 m 65.202 4.2066384316 73.4999942697 56.9040057303
C57BL/6J m 81.275 4.7031647449 90.552439632 71.997560368
DBA/2J m 96.328 4.2066384316 104.6259942697 88.0300057303




  GWAS USING LINEAR MIXED MODELS