Project measure / variable:   Auwerx1   vo2_basal_wheel_CD

ID, description, units MPD:111324   vo2_basal_wheel_CD   basal oxygen consumption, after voluntary wheel running test   [mL/kg/min]  CD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   55 strains     sex: m     age: 25wks
Procedure monitoring system
Ontology mappings

  STRAIN COMPARISON PLOT
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Auwerx1 - basal oxygen consumption, after voluntary wheel running test CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested55 strains
Mean of the strain means83.24   mL/kg/min
Median of the strain means85.71   mL/kg/min
SD of the strain means± 13.149
Coefficient of variation (CV)0.158
Min–max range of strain means53.83   –   108.9   mL/kg/min
Mean sample size per strain4.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 54 38514.009 713.2224 9.3222 < 0.0001
Residuals 177 13541.874 76.5078


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 74.12 8.0422   5 3.5966 0.1085 63.0, 83.7 -0.69
BXD100 m 93.39 13.182   3 7.6109 0.1412 78.17, 101.2 0.77
BXD101 m 91.03 4.7219   4 2.3609 0.0519 85.25, 96.42 0.59
BXD11 m 98.6 21.355   2   15.1 0.2166 83.5, 113.7 1.17
BXD12 m 88.18 8.025   5 3.5889 0.091 76.4, 95.5 0.38
BXD16 m 57.87 6.7439   4 3.3719 0.1165 51.75, 67.08 -1.93
BXD2 m 71.46 2.5714   4 1.2857 0.036 67.75, 73.5 -0.9
BXD27 m 93.88 11.399   5 5.0977 0.1214 77.5, 105.7 0.81
BXD32 m 104.8 10.162   5 4.5445 0.0969 94.5, 121.2 1.64
BXD34 m 88.23 9.4492   4 4.7246 0.1071 76.7, 99.2 0.38
BXD39 m 70.37 6.045   5 2.7034 0.0859 60.4, 74.75 -0.98
BXD40 m 78.96 11.188   3 6.4591 0.1417 70.75, 91.7 -0.33
BXD43 m 94.83 14.687   3 8.4793 0.1549 77.9, 104.1 0.88
BXD44 m 92.42 8.9516   9 2.9839 0.0969 78.42, 108.1 0.7
BXD45 m 98.9 1.7049   4 0.85245 0.0172 97.5, 101.3 1.19
BXD48 m 62.95 9.7877   5 4.3772 0.1555 53.17, 75.3 -1.54
BXD48a m 71.39 8.1837   4 4.0918 0.1146 60.5, 78.33 -0.9
BXD49 m 63.48 9.4771   4 4.7386 0.1493 49.5, 69.83 -1.5
BXD50 m 78.28 9.1025   4 4.5513 0.1163 69.9, 89.7 -0.38
BXD51 m 108.9 6.5434   4 3.2717 0.0601 104.2, 118.3 1.95
BXD53 m 84.06 9.0063   5 4.0277 0.1071 75.9, 99.0 0.06
BXD55 m 93.72 11.112   5 4.9694 0.1186 77.17, 106.5 0.8
BXD56 m 74.43 7.7623   3 4.4816 0.1043 67.3, 82.7 -0.67
BXD6 m 86.99 5.5504   5 2.4822 0.0638 80.42, 93.3 0.29
BXD60 m 73.67 9.4183   5 4.212 0.1278 67.6, 90.3 -0.73
BXD61 m 90.75 1.0672   3 0.61614 0.0118 89.83, 91.92 0.57
BXD62 m 85.71 8.423   4 4.2115 0.0983 73.5, 91.6 0.19
BXD63 m 83.92 17.25   4 8.6249 0.2055 67.83, 103.6 0.05
BXD64 m 86.4 7.506   4 3.753 0.0869 76.9, 94.8 0.24
BXD65 m 61.39 3.9841   4 1.9921 0.0649 56.67, 65.8 -1.66
BXD65a m 62.6 6.8582   5 3.0671 0.1096 58.2, 74.6 -1.57
BXD65b m 53.83 12.081   4 6.0405 0.2244 43.5, 71.2 -2.24
BXD66 m 67.14 5.9213   5 2.6481 0.0882 60.0, 74.83 -1.22
BXD67 m 74.07 7.6807   5 3.4349 0.1037 67.08, 82.5 -0.7
BXD68 m 87.77 6.9959   3 4.0391 0.0797 80.3, 94.17 0.34
BXD69 m 81.82 3.0211   5 1.3511 0.0369 78.3, 86.0 -0.11
BXD70 m 99.51 4.8378   4 2.4189 0.0486 94.25, 105.6 1.24
BXD73 m 90.98 5.9885   4 2.9943 0.0658 82.33, 95.67 0.59
BXD73a m 72.65 5.8816   4 2.9408 0.081 67.5, 78.5 -0.81
BXD73b m 64.33 12.554   3 7.2483 0.1951 50.8, 75.6 -1.44
BXD75 m 78.78 6.8192   5 3.0496 0.0866 71.75, 88.5 -0.34
BXD77 m 83.78 11.305   5 5.0558 0.1349 64.9, 92.7 0.04
BXD79 m 74.7 2.774   5 1.2406 0.0371 70.1, 77.6 -0.65
BXD8 m 107.3 5.9276   4 2.9638 0.0552 99.1, 113.2 1.83
BXD81 m 90.91 11.846   4 5.923 0.1303 81.4, 108.0 0.58
BXD83 m 93.64 5.5364   3 3.1964 0.0591 87.25, 97.0 0.79
BXD84 m 83.53 4.3668   4 2.1834 0.0523 78.8, 89.3 0.02
BXD87 m 100.7 8.1382   4 4.0691 0.0808 92.83, 110.4 1.33
BXD89 m 91.19 5.577   4 2.7885 0.0612 83.0, 95.17 0.6
BXD90 m 89.14 5.3208   4 2.6604 0.0597 86.0, 97.08 0.45
BXD95 m 70.83 18.975   4 9.4875 0.2679 43.5, 86.3 -0.94
BXD98 m 74.24 8.5968   4 4.2984 0.1158 63.9, 82.5 -0.68
BXD99 m 90.37 3.7796   5 1.6903 0.0418 86.92, 95.75 0.54
C57BL/6J m 90.95 11.408   4 5.704 0.1254 75.42, 101.8 0.59
DBA/2J m 100.2 7.6146   3 4.3963 0.076 93.75, 108.6 1.29


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 74.12 3.9117198902 81.839611788 66.400388212
BXD100 m 93.39 5.0500086633 103.3559759647 83.4240240353
BXD101 m 91.03 4.3734357918 99.6607883589 82.3992116411
BXD11 m 98.6 6.1849722109 110.8057779512 86.3942220488
BXD12 m 88.182 3.9117198902 95.901611788 80.462388212
BXD16 m 57.8725 4.3734357918 66.5032883589 49.2417116411
BXD2 m 71.4625 4.3734357918 80.0932883589 62.8317116411
BXD27 m 93.88 3.9117198902 101.599611788 86.160388212
BXD32 m 104.82 3.9117198902 112.539611788 97.100388212
BXD34 m 88.2325 4.3734357918 96.8632883589 79.6017116411
BXD39 m 70.37 3.9117198902 78.089611788 62.650388212
BXD40 m 78.9566666667 5.0500086633 88.9226426314 68.990690702
BXD43 m 94.8333333333 5.0500086633 104.799309298 84.8673573686
BXD44 m 92.4211111111 2.9156238612 98.1749700171 86.6672522051
BXD45 m 98.9 4.3734357918 107.5307883589 90.2692116411
BXD48 m 62.954 3.9117198902 70.673611788 55.234388212
BXD48a m 71.395 4.3734357918 80.0257883589 62.7642116411
BXD49 m 63.4825 4.3734357918 72.1132883589 54.8517116411
BXD50 m 78.275 4.3734357918 86.9057883589 69.6442116411
BXD51 m 108.875 4.3734357918 117.5057883589 100.2442116411
BXD53 m 84.06 3.9117198902 91.779611788 76.340388212
BXD55 m 93.716 3.9117198902 101.435611788 85.996388212
BXD56 m 74.4333333333 5.0500086633 84.399309298 64.4673573686
BXD6 m 86.994 3.9117198902 94.713611788 79.274388212
BXD60 m 73.67 3.9117198902 81.389611788 65.950388212
BXD61 m 90.75 5.0500086633 100.7159759647 80.7840240353
BXD62 m 85.7125 4.3734357918 94.3432883589 77.0817116411
BXD63 m 83.92 4.3734357918 92.5507883589 75.2892116411
BXD64 m 86.4 4.3734357918 95.0307883589 77.7692116411
BXD65 m 61.3875 4.3734357918 70.0182883589 52.7567116411
BXD65a m 62.6 3.9117198902 70.319611788 54.880388212
BXD65b m 53.825 4.3734357918 62.4557883589 45.1942116411
BXD66 m 67.14 3.9117198902 74.859611788 59.420388212
BXD67 m 74.066 3.9117198902 81.785611788 66.346388212
BXD68 m 87.7666666667 5.0500086633 97.7326426314 77.800690702
BXD69 m 81.82 3.9117198902 89.539611788 74.100388212
BXD70 m 99.5125 4.3734357918 108.1432883589 90.8817116411
BXD73 m 90.98 4.3734357918 99.6107883589 82.3492116411
BXD73a m 72.6475 4.3734357918 81.2782883589 64.0167116411
BXD73b m 64.3333333333 5.0500086633 74.299309298 54.3673573686
BXD75 m 78.78 3.9117198902 86.499611788 71.060388212
BXD77 m 83.78 3.9117198902 91.499611788 76.060388212
BXD79 m 74.7 3.9117198902 82.419611788 66.980388212
BXD8 m 107.35 4.3734357918 115.9807883589 98.7192116411
BXD81 m 90.905 4.3734357918 99.5357883589 82.2742116411
BXD83 m 93.64 5.0500086633 103.6059759647 83.6740240353
BXD84 m 83.525 4.3734357918 92.1557883589 74.8942116411
BXD87 m 100.695 4.3734357918 109.3257883589 92.0642116411
BXD89 m 91.19 4.3734357918 99.8207883589 82.5592116411
BXD90 m 89.145 4.3734357918 97.7757883589 80.5142116411
BXD95 m 70.825 4.3734357918 79.4557883589 62.1942116411
BXD98 m 74.245 4.3734357918 82.8757883589 65.6142116411
BXD99 m 90.368 3.9117198902 98.087611788 82.648388212
C57BL/6J m 90.955 4.3734357918 99.5857883589 82.3242116411
DBA/2J m 100.2 5.0500086633 110.1659759647 90.2340240353




  GWAS USING LINEAR MIXED MODELS