Project measure / variable:   Auwerx1   ogtt_ins_t15_HFD

ID, description, units MPD:111267   ogtt_ins_t15_HFD   insulin, glucose tolerance test (20% glucose oral gavage, overnight fast), after 15 min   [µg/L]  HFD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   56 strains     sex: m     age: 17wks
Procedure hormone quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Auwerx1 - insulin, glucose tolerance test (20% glucose oral gavage, overnight fast), after 15 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested56 strains
Mean of the strain means3.9173   µg/L
Median of the strain means3.6807   µg/L
SD of the strain means± 2.3833
Coefficient of variation (CV)0.6084
Min–max range of strain means0.86024   –   11.749   µg/L
Mean sample size per strain4.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 55 1285.0047 23.3637 8.2188 < 0.0001
Residuals 187 531.5883 2.8427


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 1.56 0.54139   5 0.24212 0.347 1.01, 2.45 -0.99
BXD100 m 5.2104 2.4751   5 1.1069 0.475 2.526, 8.743 0.54
BXD101 m 4.375 1.4495   4 0.72476 0.3313 3.27, 6.48 0.19
BXD11 m 4.0826 2.7708   5 1.2391 0.6787 1.0833, 6.8887 0.07
BXD12 m 1.2534 0.78224   5 0.34983 0.6241 0.672, 2.6 -1.12
BXD16 m 4.4343 2.5028   5 1.1193 0.5644 2.0691, 8.4031 0.22
BXD2 m 5.0177 2.2081   5 0.98747 0.4401 1.8074, 6.7761 0.46
BXD27 m 3.6529 2.1354   4 1.0677 0.5846 1.5214, 6.6176 -0.11
BXD32 m 6.4367 0.39311   3 0.22696 0.0611 5.99, 6.73 1.06
BXD34 m 1.9383 1.8387   5 0.8223 0.9486 0.62421, 5.1139 -0.83
BXD39 m 7.4285 1.2177   5 0.54459 0.1639 5.2992, 8.2198 1.47
BXD40 m 0.8675 0.28605   4 0.14303 0.3297 0.5, 1.16 -1.28
BXD43 m 1.1753 0.23582   3 0.13615 0.2006 0.929, 1.399 -1.15
BXD44 m 3.7086 2.3178   7 0.87603 0.625 0.957, 6.734 -0.09
BXD45 m 4.2285 1.8778   4 0.9389 0.4441 2.259, 6.516 0.13
BXD48 m 3.8782 1.5391   4 0.76956 0.3969 1.844, 5.109 -0.02
BXD48a m 11.749 0.50731   3 0.2929 0.0432 11.163, 12.052 3.29
BXD49 m 2.3535 1.1441   4 0.57205 0.4861 1.477, 3.901 -0.66
BXD50 m 5.084 1.9215   5 0.85932 0.3779 2.03, 6.69 0.49
BXD51 m 2.802 0.45443   4 0.22722 0.1622 2.43, 3.408 -0.47
BXD53 m 2.29 0.73905   5 0.33052 0.3227 1.2091, 2.888 -0.68
BXD55 m 2.172 0.4801   4 0.24005 0.221 1.871, 2.888 -0.73
BXD56 m 2.4875 0.44086   4 0.22043 0.1772 1.9, 2.95 -0.6
BXD6 m 2.8448 1.5768   5 0.70518 0.5543 0.77365, 5.1568 -0.45
BXD60 m 7.162 0.14096   5 0.06304 0.0197 6.96, 7.33 1.36
BXD61 m 10.195 3.4562   5 1.5456 0.339 4.038, 12.14 2.63
BXD62 m 4.106 1.9374   3 1.1185 0.4718 2.612, 6.295 0.08
BXD63 m 3.315 0.72346   4 0.36173 0.2182 2.295, 3.903 -0.25
BXD64 m 0.95225 0.40114   4 0.20057 0.4213 0.365, 1.241 -1.24
BXD65 m 4.441 1.3145   4 0.65727 0.296 2.615, 5.635 0.22
BXD65a m 4.7375 1.2851   4 0.64254 0.2713 3.05, 6.17 0.34
BXD66 m 8.7743 3.2355   4 1.6177 0.3687 5.197, 11.9 2.04
BXD67 m 2.0297 0.53509   5 0.2393 0.2636 1.5429, 2.7622 -0.79
BXD68 m 1.153 0.48833   4 0.24417 0.4235 0.443, 1.546 -1.16
BXD69 m 1.6037 0.73223   3 0.42275 0.4566 1.039, 2.431 -0.97
BXD70 m 3.8255 2.4529   4 1.2264 0.6412 1.2, 6.843 -0.04
BXD71 m 1.745 1.2331   4 0.61653 0.7066 0.79, 3.52 -0.91
BXD73 m 3.5633 1.0812   4 0.5406 0.3034 2.312, 4.939 -0.15
BXD73a m 4.84 2.3701   4 1.1851 0.4897 1.859, 7.643 0.39
BXD73b m 2.7762 0.92465   5 0.41352 0.3331 1.792, 4.146 -0.48
BXD75 m 7.3964 3.5845   5 1.603 0.4846 2.981, 10.915 1.46
BXD77 m 3.634 1.0984   5 0.49124 0.3023 2.04, 4.48 -0.12
BXD79 m 3.11 1.1577   5 0.51773 0.3722 1.72, 4.32 -0.34
BXD8 m 0.86024 0.41286   5 0.18464 0.4799 0.31443, 1.4071 -1.28
BXD81 m 4.5643 0.36947   3 0.21331 0.0809 4.245, 4.969 0.27
BXD83 m 8.7033 3.0301   4 1.515 0.3482 5.062, 11.581 2.01
BXD84 m 1.9197 0.79456   3 0.45874 0.4139 1.447, 2.837 -0.84
BXD85 m 2.5038 1.7264   4 0.86319 0.6895 1.323, 5.063 -0.59
BXD87 m 3.8362 0.78235   5 0.34988 0.2039 2.57, 4.719 -0.03
BXD89 m 3.7155 2.1529   4 1.0764 0.5794 0.55, 5.245 -0.08
BXD90 m 2.1505 0.26415   4 0.13207 0.1228 1.764, 2.361 -0.74
BXD95 m 3.886 1.4963   5 0.66916 0.385 1.92, 6.13 -0.01
BXD98 m 1.8154 0.64227   5 0.28723 0.3538 0.894, 2.68 -0.88
BXD99 m 2.6132 0.3003   5 0.1343 0.1149 2.238, 3.041 -0.55
C57BL/6J m 4.9827 0.8448   4 0.4224 0.1695 4.301, 6.198 0.45
DBA/2J m 7.4282 2.9834   4 1.4917 0.4016 4.131, 11.353 1.47


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 1.56 0.7540183079 3.0474753158 0.0725246842
BXD100 m 5.2104 0.7540183079 6.6978753158 3.7229246842
BXD101 m 4.375 0.8430180964 6.0380479605 2.7119520395
BXD11 m 4.08264 0.7540183079 5.5701153158 2.5951646842
BXD12 m 1.2534 0.7540183079 2.7408753158 -0.2340753158
BXD16 m 4.43426 0.7540183079 5.9217353158 2.9467846842
BXD2 m 5.0177 0.7540183079 6.5051753158 3.5302246842
BXD27 m 3.652875 0.8430180964 5.3159229605 1.9898270395
BXD32 m 6.4366666667 0.9734334498 8.356989042 4.5163442913
BXD34 m 1.93828 0.7540183079 3.4257553158 0.4508046842
BXD39 m 7.42852 0.7540183079 8.9159953158 5.9410446842
BXD40 m 0.8675 0.8430180964 2.5305479605 -0.7955479605
BXD43 m 1.1753333333 0.9734334498 3.0956557087 -0.744989042
BXD44 m 3.7085714286 0.6372617811 4.9657175205 2.4514253366
BXD45 m 4.2285 0.8430180964 5.8915479605 2.5654520395
BXD48 m 3.87825 0.8430180964 5.5412979605 2.2152020395
BXD48a m 11.7486666667 0.9734334498 13.668989042 9.8283442913
BXD49 m 2.3535 0.8430180964 4.0165479605 0.6904520395
BXD50 m 5.084 0.7540183079 6.5714753158 3.5965246842
BXD51 m 2.802 0.8430180964 4.4650479605 1.1389520395
BXD53 m 2.28998 0.7540183079 3.7774553158 0.8025046842
BXD55 m 2.172 0.8430180964 3.8350479605 0.5089520395
BXD56 m 2.4875 0.8430180964 4.1505479605 0.8244520395
BXD6 m 2.84481 0.7540183079 4.3322853158 1.3573346842
BXD60 m 7.162 0.7540183079 8.6494753158 5.6745246842
BXD61 m 10.1946 0.7540183079 11.6820753158 8.7071246842
BXD62 m 4.106 0.9734334498 6.0263223753 2.1856776247
BXD63 m 3.315 0.8430180964 4.9780479605 1.6519520395
BXD64 m 0.95225 0.8430180964 2.6152979605 -0.7107979605
BXD65 m 4.441 0.8430180964 6.1040479605 2.7779520395
BXD65a m 4.7375 0.8430180964 6.4005479605 3.0744520395
BXD66 m 8.77425 0.8430180964 10.4372979605 7.1112020395
BXD67 m 2.02972 0.7540183079 3.5171953158 0.5422446842
BXD68 m 1.153 0.8430180964 2.8160479605 -0.5100479605
BXD69 m 1.6036666667 0.9734334498 3.523989042 -0.3166557087
BXD70 m 3.8255 0.8430180964 5.4885479605 2.1624520395
BXD71 m 1.745 0.8430180964 3.4080479605 0.0819520395
BXD73 m 3.56325 0.8430180964 5.2262979605 1.9002020395
BXD73a m 4.84 0.8430180964 6.5030479605 3.1769520395
BXD73b m 2.7762 0.7540183079 4.2636753158 1.2887246842
BXD75 m 7.3964 0.7540183079 8.8838753158 5.9089246842
BXD77 m 3.634 0.7540183079 5.1214753158 2.1465246842
BXD79 m 3.11 0.7540183079 4.5974753158 1.6225246842
BXD8 m 0.860238 0.7540183079 2.3477133158 -0.6272373158
BXD81 m 4.5643333333 0.9734334498 6.4846557087 2.644010958
BXD83 m 8.70325 0.8430180964 10.3662979605 7.0402020395
BXD84 m 1.9196666667 0.9734334498 3.839989042 -0.0006557087
BXD85 m 2.50375 0.8430180964 4.1667979605 0.8407020395
BXD87 m 3.8362 0.7540183079 5.3236753158 2.3487246842
BXD89 m 3.7155 0.8430180964 5.3785479605 2.0524520395
BXD90 m 2.1505 0.8430180964 3.8135479605 0.4874520395
BXD95 m 3.886 0.7540183079 5.3734753158 2.3985246842
BXD98 m 1.8154 0.7540183079 3.3028753158 0.3279246842
BXD99 m 2.6132 0.7540183079 4.1006753158 1.1257246842
C57BL/6J m 4.98275 0.8430180964 6.6457979605 3.3197020395
DBA/2J m 7.42825 0.8430180964 9.0912979605 5.7652020395




  GWAS USING LINEAR MIXED MODELS